[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100485538":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":32,"centralContacts":40,"locations":45,"responsibleParty":78,"collaborators":80,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":92,"acronym":23,"eligibilityCriteria":93,"healthyVolunteers":94,"sex":95,"minAge":96,"maxAge":23,"enrollmentInfo":97,"targetDuration":23,"studyType":100,"phases":101,"briefSummary":103,"conditions":104,"keywords":108,"overallStatus":48,"whyStopped":23,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":126,"locationsCount":127},{"fullName":5,"class":6},"Desmond Tutu HIV Foundation","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"U=U testing messaging scripts","EXPERIMENTAL","Aim 1: Human-centred designed, behavioural nudge theory informed U=U messaging intervention to improve HIV testing uptake by men",[13],"Behavioral: U=U testing messaging scripts",{"label":15,"type":10,"description":16,"interventionNames":17},"U=U adherence messaging scripts","Aim 2: Human-centred designed, behavioural nudge theory informed U=U messaging intervention to improve ART adherence, HIV viral suppression and retention in care",[18],"Behavioral: U=U adherence messaging scripts",{"label":20,"type":21,"description":22,"interventionNames":23},"Standard of Care (SoC) messaging","NO_INTERVENTION","Aim 1: SoC messaging scripts will be used to both invite men for CB-HTS and to refer those that test HIV-positive for DoH clinic-based ART initiation\n\nAim 2: SoC messaging as part of ART initiation counselling, and as part of their HIV care and treatment program",null,[25,29],{"type":26,"name":9,"description":27,"armGroupLabels":28,"otherNames":23},"BEHAVIORAL","On site testing days randomized to the intervention, trained health promoters employed by the mobile testing venues will use U=U messaging scripts to invite men in the vicinity to seek HIV testing services on that day. On intervention days, the U=U messaging will also be used by counselors at the testing venue when referring those who test HIV positive to clinic-based ART initiation services provided by the local Department of Health",[9],{"type":26,"name":15,"description":30,"armGroupLabels":31,"otherNames":23},"After receiving standard ART initiation and adherence counselling from a DoH clinic nurse per South African National Guidelines, RCs will deliver a U=U message and hand participants a small business card with a brief U=U message on it. Participants will then receive monthly SMS booster messages (but can opt out) and monthly in-clinic booster messages during routine medical refill visits, again with a business card for messaging reinforcement.",[15],[33,37],{"name":34,"affiliation":35,"role":36},"Andrew Medina-Marino, PhD","Desmond Tutu Health Foundation","PRINCIPAL_INVESTIGATOR",{"name":38,"affiliation":39,"role":36},"Alison Buttenheim, PhD, MBA","Penn Nursing and Perelman School of Medicine, University of Pennsylvania",[41],{"name":34,"role":42,"phone":43,"phoneExt":23,"email":44},"CONTACT","+27 87 821 1109","Andrew.Marino@hiv-research.org.za",[46,64],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"countryCode":53,"cosmosGeoPoint":54,"geoPoint":59,"contacts":60},"Buffalo City Metro","RECRUITING","East London","Eastern Cape","5217","South Africa","ZA",{"type":55,"coordinates":56},"Point",[57,58],27.91162,-33.01529,{"lat":58,"lon":57},[61,62,63],{"name":34,"role":42,"phone":43,"phoneExt":23,"email":44},{"name":34,"role":36,"phone":23,"phoneExt":23,"email":23},{"name":38,"role":36,"phone":23,"phoneExt":23,"email":23},{"facility":65,"status":48,"city":66,"state":67,"zip":68,"country":52,"countryCode":53,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Cape Town Metro","Cape Town","Western Cape","7405",{"type":55,"coordinates":70},[71,72],18.42322,-33.92584,{"lat":72,"lon":71},[75,76,77],{"name":34,"role":42,"phone":43,"phoneExt":23,"email":44},{"name":34,"role":36,"phone":23,"phoneExt":23,"email":23},{"name":38,"role":36,"phone":23,"phoneExt":23,"email":23},{"type":79,"investigatorFullName":23,"investigatorTitle":23,"investigatorAffiliation":23,"oldNameTitle":23,"oldOrganization":23},"SPONSOR",[81,84,86],{"name":82,"class":83},"National Institute of Mental Health (NIMH)","NIH",{"name":85,"class":83},"National Institutes of Health (NIH)",{"name":87,"class":6},"University of Pennsylvania","100485538","improving-hiv-testing-linkage-and-retention-in-care-for-men-through-uu-messaging-100485538",false,"NCT05602376","Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging","Inclusion Criteria:\n\nAIM 1:\n\n1. male\n2. aged ≥15 years\n3. present a study issued invitation card to site receptionist\n4. ability to provide informed consent.\n\nAIM 2:\n\n1. cis-gender men\n2. aged ≥15 years\n3. newly initiating ART (i.e., treatment naïve) or re-initiating ART after 6 months of being lost-to-care\n4. live in Buffalo City or Cape Town Metro Health Districts\n5. provide written informed consent",true,"MALE","15 Years",{"count":98,"type":99},3642,"ESTIMATED","INTERVENTIONAL",[102],"NA","This study will evaluate the impact of U=U messaging and counseling on gaps in the HIV care cascade for men, including testing uptake and ART initiation (Aim 1), achieving viral suppression and retention in care (Aim 2) in two provinces in South Africa. The U=U message communicates the compelling idea that PLHIV who take ART and have an undetectable viral load (\\\u003C200 copies\u002FmL) cannot sexually transmit HIV. Additionally, the investigators will conduct a multi-method evaluation to inform future implementation of U=U messaging interventions (Aim 3).",[105,106,107],"HIV Infections","Men","Treatment Adherence",[109,110,106,111,112,113,114,115,116,117],"HIV","HIV testing","U=U","Viral suppression","Treatment as Prevention","Viral load","ART uptake","Undetectable","Untransmittable","2024-10-30",{"date":120,"type":121},"2024-11-01","ACTUAL",{"date":123,"type":121},"2023-03-31",{"date":125,"type":99},"2027-05-31",{"name":5,"class":6},2]