[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100481393":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":37,"centralContacts":42,"locations":48,"responsibleParty":65,"collaborators":68,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":81,"minAge":82,"maxAge":32,"enrollmentInfo":83,"targetDuration":32,"studyType":86,"phases":87,"briefSummary":89,"conditions":90,"keywords":93,"overallStatus":50,"whyStopped":32,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":107},{"fullName":5,"class":6},"The University of Tennessee, Knoxville","OTHER",[8,14,18,23],{"label":9,"type":10,"description":11,"interventionNames":12},"Patients - Attention Only","ACTIVE_COMPARATOR","Patients with a confirmed diagnosis of heart failure.",[13],"Behavioral: Attention Control",{"label":15,"type":10,"description":16,"interventionNames":17},"Care Partners - Attention Only","Care partners of patients with a confirmed diagnosis of heart failure.",[13],{"label":19,"type":20,"description":11,"interventionNames":21},"Patients - FamLit","EXPERIMENTAL",[22],"Behavioral: FamLit",{"label":24,"type":20,"description":16,"interventionNames":25},"Care Partners - FamLit",[22],[27,33],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"BEHAVIORAL","FamLit","The FamLit (Family-focused and Literacy-sensitive strategy) is an interactive, multi-component intervention supported by the FamLit intervention Guide, including both spoken and printed materials written at a 4th-grade reading level for HF patients and their primary CPs.Three constructs guide the intervention, based on the Theory of Planned Behavior (TPB): 1) develop patient and CP positive attitudes through HF instruction and teach-back; 2) form positive subjective norms through coaching to improve patient and CP communication, support, and teamwork; and 3) increase perceived behavioral control through coaching and role-playing to empower patients and CPs to overcome individual barriers to adherence. This intervention also includes use of the SimpleMed+ electronic pillbox.",[24,19],null,{"type":28,"name":34,"description":35,"armGroupLabels":36,"otherNames":32},"Attention Control","Participants in this group will talk with an interventionist to discuss general health. This intervention also includes use of the SimpleMed+ electronic pillbox.",[15,9],[38],{"name":39,"affiliation":40,"role":41},"Jia-Rong Wu","University of Kentucky","PRINCIPAL_INVESTIGATOR",[43],{"name":44,"role":45,"phone":46,"phoneExt":32,"email":47},"Jia-Rong Wu, PhD","CONTACT","8593234712","jiarong.wu2@uky.edu",[49],{"facility":39,"status":50,"city":51,"state":52,"zip":53,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"RECRUITING","Lexington","Kentucky","40536","United States","US",{"type":57,"coordinates":58},"Point",[59,60],-84.47772,37.98869,{"lat":60,"lon":59},[63],{"name":44,"role":45,"phone":64,"phoneExt":32,"email":47},"859-323-4712",{"type":66,"investigatorFullName":39,"investigatorTitle":67,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"SPONSOR_INVESTIGATOR","Professor",[69],{"name":70,"class":71},"National Institute of Nursing Research (NINR)","NIH","100481393","improving-medication-adherence-using-family-focused-and-literacy-sensitive-strategies-100481393",false,"NCT05548413","Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies","Improving Medication Adherence Using Family-focused and Literacy-sensitive Strategies in Patients With Heart Failure","FamLit_HF","Inclusion Criteria - Patient Participants:\n\n* confirmed diagnosis of heart failure (HF), either systolic or diastolic HF\n* ave suboptimal medication adherence\n* have a care partner (CP) (either spouse, daughter\u002Fson, partner, other relative, friend) who is identified by the patient as the person most involved in HF care\n* willingness to have a CP be involved in their medication taking\n* have undergone evaluation of HF and prescribed stable doses of HF medications for at least 3 months\n* live in a setting where the patient is responsible for their ow medication administration\n* willing to use the SimpleMed+ (i.e., an electronic pillbox to measure objective medication adherence)\n* availability by phone\n\nExclusion Criteria - Patient Participants:\n\n* cognitive impairment as indicated by having difficulties to understand and give informed consent\n* a recent hospitalization within 3 months of study enrollment\n* co-existing end-stage renal disease or terminal illness such as advanced malignancy, or any other condition with less than 1-year life expectancy\n* psychotic illness\n* current alcohol dependence or other substance abuse\n* inability to speak English or other communication barrier\n* currently or have received any similar self-care intervention recently in the past year\n\nInclusion Criteria - Care Partners:\n\n* unpaid family member, friend, partner, or other relation who is involved in the patients' care at least 3 times a week, designated by the patient\n* willing to receive interventions with the patient together\n* 18 years of age or older\n\nExclusion Criteria - Care Partners:\n\n* cognitive impairment as indicated by having difficulties to understand and give informed consent\n* coexisting terminal illness\n* non-English speaking or any other communication barrier",true,"ALL","18 Years",{"count":84,"type":85},328,"ESTIMATED","INTERVENTIONAL",[88],"NA","People with heart failure who do not take their medications as prescribed are at high risk of complications leading to hospitalization, death and poor quality of life. In the proposed intervention, nurses will use easy-to-understand language to coach patients and their care partners to help them work together and build skills to overcome their individual barriers to adherence in order to 1) improve and sustain patient medication adherence; 2) reduce hospitalization; 3) improve quality of life. If effective, this intervention will support long-term medication adherence, thus reducing hospitalizations related to heart failure and quality of life.",[91,92],"Medication Adherence","Heart Failure",[94,95,96,97],"care partner","family","health literacy","teach back","2026-04-29",{"date":100,"type":101},"2026-05-05","ACTUAL",{"date":103,"type":101},"2023-01-04",{"date":105,"type":85},"2027-12-31",{"name":39,"class":6},1]