[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594710":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":30,"responsibleParty":51,"collaborators":19,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":19,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":19,"enrollmentInfo":62,"targetDuration":19,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":32,"whyStopped":19,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Icahn School of Medicine at Mount Sinai","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"World Trade Center (WTC) Responders","EXPERIMENTAL","World Trade Center (WTC) rescue and recovery workers (responders).",[13],"Other: Educational brochure for deprescribing",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Educational brochure for deprescribing","Study participant will be provided information (i.e., educational brochure) about one of the five medication classes participants may be taking that are known to have potential side effects for older adults: proton pump inhibitors (PPIs), benzodiazepine (BZs) and non-benzodiazepine sedative hypnotics (\"Z-drugs\"), first-generation antihistamines (FGA), and skeletal muscle relaxants (SMR) to determine their necessity.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Fred Ko, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Patricia Kim","CONTACT","212-241-9370","patricia.kim@mssm.edu",[31],{"facility":5,"status":32,"city":33,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","New York","10029","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-74.00597,40.71427,{"lat":41,"lon":40},[44,46,49],{"name":22,"role":27,"phone":28,"phoneExt":19,"email":45},"fred.ko@mssm.edu",{"name":47,"role":27,"phone":48,"phoneExt":19,"email":29},"Patricia Kim, MBS","201-232-8578",{"name":50,"role":23,"phone":19,"phoneExt":19,"email":19},"Fred Ko",{"type":23,"investigatorFullName":50,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Associate Professor","100594710","improving-medication-management-in-world-trade-center-responders-100594710",false,"NCT07022990","Improving Medication Management in World Trade Center Responders","Promoting Healthy Aging Among WTC Responders: Frailty Trajectories And Intervention Strategies","Inclusion Criteria:\n\n* A WTC responder already enrolled in the \"Promoting Healthy Aging Among WTC Responders: Frailty Trajectories and Intervention Strategies\" study cohort\n* aged 50 years or older, and\n* taking one of the five medication classes:\n\n  * proton pump inhibitors (PPIs),\n  * benzodiazepine (BZs) and\n  * non-benzodiazepine sedative hypnotics (\"Z-drugs\"),\n  * first-generation antihistamines (FGA), and\n  * skeletal muscle relaxants (SMR).\n\nExclusion Criteria:\n\n* None","ALL","50 Years",{"count":63,"type":64},50,"ESTIMATED","INTERVENTIONAL",[67],"NA","By 2030, the majority of World Trade Center (WTC) rescue and recovery workers (responders) will be aged 65 and over and at risk for aging-related conditions and consequences including the concurrent use of five or more medications (i.e., polypharmacy). The purpose of this research study is to investigate an educational approach targeting polypharmacy through de-prescribing unnecessary and burdensome medications via the support of informed discussions between WTC responders and their prescribing physicians.",[70],"Polypharmacy",[72,73],"Deprescribe","Medication management","2025-06-08",{"date":76,"type":77},"2025-06-15","ACTUAL",{"date":79,"type":77},"2025-04-08",{"date":81,"type":64},"2026-06-30",{"name":5,"class":6},1]