[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100522430":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":31,"locations":41,"responsibleParty":70,"collaborators":24,"id":72,"slug":73,"hasResults":74,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":74,"sex":80,"minAge":81,"maxAge":24,"enrollmentInfo":82,"targetDuration":24,"studyType":85,"phases":86,"briefSummary":88,"conditions":89,"keywords":96,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":109},{"fullName":5,"class":6},"Sunnybrook Health Sciences Centre","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Immediate start of hyperbaric treatments","EXPERIMENTAL","HBOT treatments will be scheduled to start immediately after referral.",[13],"Device: Monoplace Hyperbaric Chamber (Class III medical device).",{"label":15,"type":10,"description":16,"interventionNames":17},"Delayed start of hyperbaric treatments","HBOT treatments will be scheduled to start 60 days after referral.",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Monoplace Hyperbaric Chamber (Class III medical device).","40 hyperbaric oxygen therapy (HBOT) treatments (90 minute exposures at 2 atmospheres (ATM) per treatment), scheduled daily from Monday to Friday (i.e., 5 treatments per week) until treatments are completed (approximately 8 weeks). Treatments will be delivered in a medical grade, Health Canada-approved monoplace hyperbaric chamber and overseen by specialist hyperbaric physicians and a Certified Hyperbaric Technologist.\n\nDevice is being used in manner consistent with approved usage in Canada.",[15,9],null,[26,29],{"name":27,"affiliation":5,"role":28},"Fahad Alam, MD","PRINCIPAL_INVESTIGATOR",{"name":30,"affiliation":5,"role":28},"Jordan Tarshis, MD",[32,36],{"name":27,"role":33,"phone":34,"phoneExt":24,"email":35},"CONTACT","416-480-4864","fahad.alam@sunnybrook.ca",{"name":37,"role":33,"phone":38,"phoneExt":39,"email":40},"Lilia Kaustov, PhD","416 480-6100","89607","lilia.kaustov@sunnybrook.ca",[42],{"facility":5,"status":43,"city":44,"state":45,"zip":46,"country":47,"countryCode":48,"cosmosGeoPoint":49,"geoPoint":54,"contacts":55},"RECRUITING","Toronto","Ontario","M4N3M5","Canada","CA",{"type":50,"coordinates":51},"Point",[52,53],-79.39864,43.70643,{"lat":53,"lon":52},[56,57,59,62,64,66,68],{"name":27,"role":33,"phone":34,"phoneExt":24,"email":35},{"name":58,"role":28,"phone":24,"phoneExt":24,"email":24},"Jordan Tarshis, MD,FRCPC",{"name":60,"role":61,"phone":24,"phoneExt":24,"email":24},"Oskar Singer, MD,FRCPC","SUB_INVESTIGATOR",{"name":63,"role":61,"phone":24,"phoneExt":24,"email":24},"Stephen Choi, MD,FRCPC",{"name":65,"role":61,"phone":24,"phoneExt":24,"email":24},"Peter Giacobbe, MD",{"name":67,"role":61,"phone":24,"phoneExt":24,"email":24},"Stanley Hamstra, PhD",{"name":69,"role":61,"phone":24,"phoneExt":24,"email":24},"Adrienne Chan, MD",{"type":71,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100522430","improving-post-covid-19-syndrome-with-hyperbaric-oxygen-treatments-100522430",false,"NCT06082518","Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments","Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments (PCS-HBOT Study)","PCS-HBOT","Inclusion Criteria:\n\n1. Age ≥ 18 years old\n2. Officially diagnosed with post COVID-19 condition by a healthcare practitioner\n3. At least three months since SARS-CoV-2 infection\n4. Symptoms that persist more than 12 weeks:\n\n   * Chronic fatigue (must include) along with one of the following symptoms:\n   * Difficulty thinking or problem solving ('brain fog')\n   * Stress or anxiety\n\nExclusion Criteria:\n\n1. Contraindications\u002Fmedically unfit to receive hyperbaric treatments at an outpatient facility (pneumothorax, in-patients, requiring infusions to maintain hemodynamics, active and unstable coronary disease)\n2. Patients with cognitive difficulties and\u002For mental retardation before COVID diagnosis\n3. History of traumatic brain injury\n4. Unlikely to comply with follow-up assessments (e.g. no fixed address, plans to move out of town)\n5. Known pregnancy or planning a pregnancy in women of childbearing age","ALL","18 Years",{"count":83,"type":84},40,"ESTIMATED","INTERVENTIONAL",[87],"NA","Over 500 million people have been infected with COVID-19, and to date, more than 6 million people have died. Many individuals who have recovered from COVID-19 continue to experience symptoms even after they have been \"cured\" of the disease. This condition is known as post COVID-19 condition, which can have serious health consequences. A common symptom among these individuals is chronic fatigue, characterized by persistent tiredness or lack of energy. This study aims to explore a novel treatment for symptoms of post COVID-19 condition, known as hyperbaric oxygen therapy. This approach has shown promise in helping people with post COVID-19 conditions and treating some other causes of fatigue.\n\nHyperbaric oxygen therapy involves placing patients in a small chamber where they receive high oxygen gas levels. However, this treatment is expensive and time-consuming, and it is unclear if this treatment can be effectively assessed in a large-scale research study. This small study will help us decide if conducting a large research study is feasible. The investigators aim to assess if hyperbaric oxygen therapy can improve symptoms of post COVID-19 condition, such as fatigue.",[90,91,92,93,94,95],"Post COVID-19 Condition","Post-COVID-19 Syndrome","Post-COVID Syndrome","COVID-19","Fatigue","Fatigue Syndrome, Chronic",[97,98,90,94,99,93],"Hyperbaric Oxygen Therapy","HBOT","Severe Acute Respiratory Syndrome-CoV-2","2026-03-12",{"date":102,"type":103},"2026-03-16","ACTUAL",{"date":105,"type":103},"2024-01-02",{"date":107,"type":84},"2027-05",{"name":5,"class":6},1]