[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100335345":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":34,"locations":40,"responsibleParty":66,"collaborators":18,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":77,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":18,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":18,"overallStatus":42,"whyStopped":18,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"Texas A&M University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Midline traction oral appliance","EXPERIMENTAL","Subjects will wear the oral appliance nightly for 4 weeks. Must snore or have other evidence of sleep disordered breathing.",[13],"Device: Midline traction oral appliance",{"label":15,"type":16,"description":17,"interventionNames":18},"Control","NO_INTERVENTION","Subjects who do do not wish to wear the oral appliance will have their sleep monitored in parallel to the experimental subjects for 4 weeks.",null,[20],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Device positions the mandible forward to open airway; device can be titrated to gradually advance the mandible.",[9],[25,26],"MyTAP oral appliance","Mandibular advancement device",[28,32],{"name":29,"affiliation":30,"role":31},"Emet D Schneiderman, PhD","Texas A&M University College of Dentistry","PRINCIPAL_INVESTIGATOR",{"name":33,"affiliation":30,"role":31},"Preetam J Schramm, PhD",[35],{"name":36,"role":37,"phone":38,"phoneExt":18,"email":39},"Zohre German, MS","CONTACT","214-828-8291","german@tamhsc.edu",[41],{"facility":30,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Dallas","Texas","75246","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-96.80667,32.78306,{"lat":52,"lon":51},[55,57,60,62,64],{"name":36,"role":37,"phone":38,"phoneExt":18,"email":56},"german@tamu.edu",{"name":58,"role":59,"phone":18,"phoneExt":18,"email":18},"Jason Hui, DDS","SUB_INVESTIGATOR",{"name":61,"role":59,"phone":18,"phoneExt":18,"email":18},"Duane Wilson, DDS",{"name":63,"role":59,"phone":18,"phoneExt":18,"email":18},"Ann McCann, PhD",{"name":65,"role":59,"phone":18,"phoneExt":18,"email":18},"Pollyana Moura, DDS",{"type":31,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Emet D. Schneiderman, PhD","Professor, Biomedical Sciences","100335345","improving-sleep-quality-during-pregnancy-using-an-oral-appliance-100335345",false,"NCT03646214","Improving Sleep Quality During Pregnancy Using an Oral Appliance","Oral Appliance Therapy for Improving Sleep Quality During Pregnancy: A Controlled Clinical Trial","PREGNCCT","Inclusion Criteria:\n\n* Pregnant adults who snore\n* At least 8 teeth per arch\n* Mallampati score from I to II\n* Palatine tonsils grade 0,1 or 2\n* Capable of giving verbal and written informed consent\n* Able to apply the sleep recorder and the oral appliance.\n\nExclusion Criteria:\n\n* Pregnant \\> 32 weeks\n* Uncontrolled serious health issues\n* Cardiovascular or cardiac rhythm disorders\n* Pharmacological dependency\n* Concomitant use of hypnotic agents or other sleep aids, nicotine or alcohol\n* Ongoing temporomandibular joint disorders\n* Loose teeth or periodontal disease\n* History of uvulopalatopharyngoplasty (UPPP)",true,"FEMALE","18 Years","45 Years",{"count":82,"type":83},20,"ESTIMATED","INTERVENTIONAL",[86],"NA","Many pregnant women suffer from poor sleep quality and snoring. Evidence shows an increasing association between (1) sleep disordered breathing and (2) maternal cardiovascular disease and in-hospital death. Snoring is a variant of obstructive sleep apnea (OSA) and OSA during pregnancy is associated with higher risks for cesarean delivery, gestational hypertension, preeclampsia and preterm delivery. It may also impact fetal outcomes negatively. The purpose of this study is to determine whether sleep quality can be improved in pregnant women who snore by means of an oral appliance that opens the airway. Sleep quality is evaluated objectively using an un-intrusive home sleep test system.",[89,90],"Snoring","Sleep Fragmentation","2025-10-01",{"date":93,"type":94},"2025-10-07","ACTUAL",{"date":96,"type":94},"2018-02-01",{"date":98,"type":83},"2026-07-30",{"name":5,"class":6},1]