[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100531050":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":42,"centralContacts":47,"locations":52,"responsibleParty":69,"collaborators":71,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":90,"sex":96,"minAge":97,"maxAge":98,"enrollmentInfo":99,"targetDuration":12,"studyType":102,"phases":103,"briefSummary":105,"conditions":106,"keywords":108,"overallStatus":54,"whyStopped":12,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"Nationwide Children's Hospital","OTHER",[8,13,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"Baseline phase","NO_INTERVENTION","During this arm, sites will provide routine care.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Adoption phase","EXPERIMENTAL","Following the dissemination visit, sites will actively work to implement the bundle of interventions.",[18],"Other: Quality improvement bundle",{"label":20,"type":15,"description":21,"interventionNames":22},"Sustain phase","During this arm, sites will actively work to sustain the implemented interventions and will be allowed to develop site-specific plan-do-study-act cycles in order to address site-specific key drivers with central data and methodological support.",[23],"Other: Quality improvement bundle and local PDSA cycles with central support",{"label":25,"type":15,"description":26,"interventionNames":27},"Independent phase","During this arm, sites will continue to sustain the implemented interventions and develop site-specific plan-do-study-act cycles in order to address site-specific key drivers without central data and methodological support.",[28],"Other: Quality improvement bundle and local PDSA cycles without central support",[30,34,38],{"type":6,"name":31,"description":32,"armGroupLabels":33,"otherNames":12},"Quality improvement bundle","(1) standardizing BZD default to intranasal or buccal midazolam; (2) targeting initial BZD treatment within 10 minutes of seizure onset; (3) relocating and bundling all administration items needed to the hospital unit medication room; (4) utilizing basic seizure first aid in the initial patient assessment; (5) developing and implementing SE-specific EHR documentation; (6) multidisciplinary QI teams",[14],{"type":6,"name":35,"description":36,"armGroupLabels":37,"otherNames":12},"Quality improvement bundle and local PDSA cycles with central support","Sites will implement both the standard QI bundle as well as site-specific PDSA cycles with central data and methods support.",[20],{"type":6,"name":39,"description":40,"armGroupLabels":41,"otherNames":12},"Quality improvement bundle and local PDSA cycles without central support","Sites will implement both the standard QI bundle as well as site-specific PDSA cycles without central data or methods support.",[25],[43],{"name":44,"affiliation":45,"role":46},"Adam Ostendorf, MD","Nationwide Children's Hospital and The Ohio State University","PRINCIPAL_INVESTIGATOR",[48],{"name":44,"role":49,"phone":50,"phoneExt":12,"email":51},"CONTACT","614-722-5145","adam.ostendorf@nationwidechildrens.org",[53],{"facility":5,"status":54,"city":55,"state":56,"zip":57,"country":58,"countryCode":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"RECRUITING","Columbus","Ohio","43205","United States","US",{"type":61,"coordinates":62},"Point",[63,64],-82.99879,39.96118,{"lat":64,"lon":63},[67],{"name":68,"role":49,"phone":50,"phoneExt":12,"email":51},"Adam P Ostendorf, MD",{"type":70,"investigatorFullName":12,"investigatorTitle":12,"investigatorAffiliation":12,"oldNameTitle":12,"oldOrganization":12},"SPONSOR",[72,74,76,78,80,82,84,86],{"name":73,"class":6},"Children's Hospital of Philadelphia",{"name":75,"class":6},"Boston Children's Hospital",{"name":77,"class":6},"Children's National Research Institute",{"name":79,"class":6},"Children's Hospital and Health System Foundation, Wisconsin",{"name":81,"class":6},"UVA Children's Hospital",{"name":83,"class":6},"Seattle Children's Hospital",{"name":85,"class":6},"Phoenix Children's Hospital",{"name":87,"class":6},"Emory University","100531050","improving-status-epilepticus-treatment-times-100531050",false,"NCT06194747","Improving Status Epilepticus Treatment Times","Quality Improvement in Time to Treatment of Status Epilepticus","QuITT-SE","Inclusion Criteria:\n\n* SE episode occurs in a male or female child aged between \\> 30 days to \\\u003C 19 years\n* Seizures meeting AT LEAST ONE of the following criteria:\n\n  1. continuous clinically apparent seizure lasting greater than 5 minutes\n  2. continuous clinically apparent seizure of any duration receiving BZD\n  3. repeated seizures without return to neurological baseline within 5 minutes\n\nExclusion Criteria:\n\n* SE episode occurs in a child with infantile spasms\n* SE episode occurs in a child with electrographic-only seizures without clinical signs other than encephalopathy","ALL","30 Days","18 Years",{"count":100,"type":101},450,"ESTIMATED","INTERVENTIONAL",[104],"NA","This is a stepped-wedge cluster randomized effectiveness-implementation hybrid study aimed at determining the effect of dissemination of a QI bundle on the time to treatment of SE among hospitalized, non-critically ill children. The primary study endpoint is to decrease the time from the SE diagnosis to treatment with the first dose of a benzodiazepine (BZD) as measured during hospitalization, which will decrease chances of morbidity and mortality.",[107],"Status Epilepticus",[107,109,110],"Quality Improvement","Interventions","2026-03-27",{"date":113,"type":114},"2026-04-01","ACTUAL",{"date":116,"type":114},"2024-02-01",{"date":118,"type":101},"2027-03-31",{"name":5,"class":6},1]