[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100642728":3},{"organization":4,"armGroups":7,"interventions":34,"overallOfficials":33,"centralContacts":48,"locations":58,"responsibleParty":75,"collaborators":79,"id":82,"slug":83,"hasResults":84,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":90,"sex":91,"minAge":92,"maxAge":33,"enrollmentInfo":93,"targetDuration":33,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":102,"overallStatus":107,"whyStopped":33,"lastUpdateSubmitDate":108,"lastUpdatePostDateStruct":109,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":117},{"fullName":5,"class":6},"Capital Medical University","OTHER",[8,15,20,25,29],{"label":9,"type":10,"description":11,"interventionNames":12},"3M-6D education GPT Group","EXPERIMENTAL","Participants will first be trained in 3M-6D education, then use ChatGPT to complete a consultation task in unrestricted natural language in approximately 10 minutes.",[13,14],"Behavioral: three minutes six dimensions education","Other: ChatGPT",{"label":16,"type":10,"description":17,"interventionNames":18},"3M-6D education Gemini Group","Participants will first be trained in 3M-6D education, then use Gemini to complete a consultation task in unrestricted natural language in approximately 10 minutes.",[13,19],"Other: Gemini",{"label":21,"type":22,"description":23,"interventionNames":24},"GPT Group","ACTIVE_COMPARATOR","Participants will use ChatGPT to complete a consultation task in unrestricted natural language in approximately 10 minutes.",[14],{"label":26,"type":22,"description":27,"interventionNames":28},"Gemini Group","Participants will use Gemini to complete a consultation task in unrestricted natural language in approximately 10 minutes.",[19],{"label":30,"type":31,"description":32,"interventionNames":33},"Control group","NO_INTERVENTION","Participants will use non-AI tools such as internet searches and medical websites to complete a consultation task in unrestricted natural language in approximately 10 minutes.",null,[35,40,44],{"type":36,"name":37,"description":38,"armGroupLabels":39,"otherNames":33},"BEHAVIORAL","three minutes six dimensions education","3M-6D education is designed based on Cognitive Load Theory to reduce the cognitive burden on patients during medical interactions with AI and to improve the clarity and completeness of symptom reporting.\n\nGuided by cognitive load theory and the natural process physicians use to take medical histories, the investigators identified candidate information dimensions and developed a structured expression framework with six dimensions for public health queries through a Delphi expert consensus process. Participants were instructed to use the framework to describe their symptoms across these six dimensions; this process can typically be completed within three minutes, so the investigators call this approach three minutes six dimensions education (3M-6D education).",[9,16],{"type":6,"name":41,"description":42,"armGroupLabels":43,"otherNames":33},"ChatGPT","Participants use ChatGPT to complete a standardized simulated clinical scenarios in unrestricted natural language.",[9,21],{"type":6,"name":45,"description":46,"armGroupLabels":47,"otherNames":33},"Gemini","Participants use Gemini to complete a standardized simulated clinical scenarios in unrestricted natural language.",[16,26],[49,54],{"name":50,"role":51,"phone":52,"phoneExt":33,"email":53},"Xunming Ji","CONTACT","01083198962","jixm@ccmu.edu.cn",{"name":55,"role":51,"phone":56,"phoneExt":33,"email":57},"Chuanjie Wu","01083199439","wuchuanjie@ccmu.edu.cn",[59],{"facility":60,"status":33,"city":61,"state":62,"zip":63,"country":64,"countryCode":65,"cosmosGeoPoint":66,"geoPoint":71,"contacts":72},"Xuanwu Hospital, Capital Medical University","Beijing","Beijing Municipality","100053","China","CN",{"type":67,"coordinates":68},"Point",[69,70],116.39723,39.9075,{"lat":70,"lon":69},[73],{"name":55,"role":51,"phone":74,"phoneExt":33,"email":57},"010-83199439",{"type":76,"investigatorFullName":77,"investigatorTitle":78,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"PRINCIPAL_INVESTIGATOR","Ji Xunming,MD,PhD","Principal Investigator",[80],{"name":81,"class":6},"Xuanwu Hospital, Beijing","100642728","improving-the-reliability-of-llms-as-medical-assistants-for-the-general-public-100642728",false,"NCT07651280","Improving the Reliability of LLMs as Medical Assistants for the General Public","Improving the Reliability of LLMs as Medical Assistants for the General Public: a Proof of Concept Simulation Trial","LAMP-1","Inclusion Criteria:\n\n1. Age 18 years or greater, male or female;\n2. Completed primary school or higher education;\n3. Able to use a smartphone or computer to complete online interaction;\n4. No history of acute ischemic stroke, systemic lupus erythematosus, gastric ulcer, pneumonia, acute cardiac infarction, urinary tract infection, uterine fibroids, diabetes, osteoarthritis, or migraine.\n5. Able to understand and comply with study procedures and to provide written informed consent.\n\nExclusion Criteria:\n\n1. Currently or previously employed as a healthcare worker;\n2. Previously received systematic medical training;\n3. Currently involved in concurrent research that may interfere with the results of the present trial;\n4. The investigator considered that the participant had other conditions that might affect compliance or preclude participation.",true,"ALL","18 Years",{"count":94,"type":95},525,"ESTIMATED","INTERVENTIONAL",[98],"NA","This study will evaluate whether three-minute six-dimensions education(3M-6D education) can improve the reliability of large language models as medical assistants for the general public. Participants will be randomly assigned to receive or not receive 3M-6D education and then use ChatGPT, Gemini, or non-AI information resources. The study will assess relevant condition identification, disposition concordance, red-flag identification, and NASA-TLX score.",[101],"Relevant Conditions Identification",[103,104,105,106],"3M-6D education","Large Language Models","relevant conditions identification","Cognitive Load Theory","NOT_YET_RECRUITING","2026-06-22",{"date":110,"type":111},"2026-06-25","ACTUAL",{"date":113,"type":95},"2026-06-20",{"date":115,"type":95},"2026-07-20",{"name":5,"class":6},1]