[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100496624":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":46,"centralContacts":51,"locations":57,"responsibleParty":73,"collaborators":36,"id":76,"slug":77,"hasResults":78,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":36,"studyType":91,"phases":92,"briefSummary":94,"conditions":95,"keywords":36,"overallStatus":59,"whyStopped":36,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Bispebjerg Hospital","OTHER",[8,15,19,24],{"label":9,"type":10,"description":11,"interventionNames":12},"1) Electrical stimulation + growth hormone","EXPERIMENTAL","One bout of electrical stimulation with 200 eccentric contractions. This is followed by daily injections with somatropin (33.3 ug\u002Fkg in the first week, 50 ug\u002Fkg in the second week) for two weeks.",[13,14],"Procedure: Electrical stimulation","Drug: Growth hormone (somatropin)",{"label":16,"type":10,"description":17,"interventionNames":18},"2) Electrical stimulation","One bout of electrical stimulation with 200 eccentric contractions",[13],{"label":20,"type":21,"description":22,"interventionNames":23},"3) Growth hormone","ACTIVE_COMPARATOR","Daily injections with somatropin (33.3 ug\u002Fkg in the first week, 50 ug\u002Fkg in the second week) for two weeks.",[14],{"label":25,"type":26,"description":27,"interventionNames":28},"4) Control","PLACEBO_COMPARATOR","No intervention",[29],"Other: Control (No electrical stimulation, nor growth hormone)",[31,37,42],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"PROCEDURE","Electrical stimulation","Experimentally induced muscly injury via. neuromuscular electrical stimulation of the hamstring muscles",[9,16],null,{"type":38,"name":39,"description":40,"armGroupLabels":41,"otherNames":36},"DRUG","Growth hormone (somatropin)","Daily injection of growth hormone",[9,20],{"type":6,"name":43,"description":44,"armGroupLabels":45,"otherNames":36},"Control (No electrical stimulation, nor growth hormone)","No electrical stimulation, nor growth hormone",[25],[47],{"name":48,"affiliation":49,"role":50},"Grith Højfeldt, PhD","Institute of Sports Medicine, Bispebjerg Hospital","PRINCIPAL_INVESTIGATOR",[52],{"name":53,"role":54,"phone":55,"phoneExt":36,"email":56},"Grith Stougaard Højfeldt, PhD","CONTACT","+45 61651061","grith.stougaard.hoejfeldt@regionh.dk",[58],{"facility":5,"status":59,"city":60,"state":36,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"RECRUITING","Copenhagen","2400","Denmark","DK",{"type":65,"coordinates":66},"Point",[67,68],12.56553,55.67594,{"lat":68,"lon":67},[71],{"name":53,"role":54,"phone":72,"phoneExt":36,"email":56},"+4561651061",{"type":50,"investigatorFullName":74,"investigatorTitle":75,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"Grith Højfeldt","Principal Investigator","100496624","improving-tissue-repair-after-injury-in-the-muscle-tendon-interface-muscle-tissue-injury-100496624",false,"NCT05746650","Improving Tissue Repair After Injury in the Muscle-tendon Interface Muscle Tissue Injury","Regulation of Protein Turnover in Connective Tissue From Muscle and Tendon Following Muscle Tissue Injury","GH-MTJ","Inclusion Criteria:\n\n* Healthy men and women scheduled to undergo reconstructive knee surgery\n* BMI 18-35\n\nExclusion Criteria:\n\n* Former or current use of growth hormone or anabolic steroids\n* Use of corticosteroids in the past 3 months\n* Use of any medication known to affect muscle or tendon turnover\n* Former participation in a study using deuterated water\n* Chronic diseases",true,"ALL","18 Years","35 Years",{"count":89,"type":90},40,"ESTIMATED","INTERVENTIONAL",[93],"NA","The study is a 2-week human study where 40 patients who are scheduled to undergo reconstructive knee surgery are randomized to administration of GH or placebo following or without neuromuscular electrical stimulation of hamstring muscles.The overall aim is to determine, the role of muscle connective tissue protein synthesis in muscle injury and repair.",[96],"Muscle Injury","2025-09-19",{"date":99,"type":100},"2025-09-24","ACTUAL",{"date":102,"type":100},"2023-02-24",{"date":104,"type":90},"2027-09-01",{"name":5,"class":6},1]