[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100626368":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":44,"responsibleParty":61,"collaborators":26,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":65,"sex":71,"minAge":72,"maxAge":26,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":46,"whyStopped":26,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Insel Gruppe AG, University Hospital Bern","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Advanced Cardiac Life Support (ACLS) alone","ACTIVE_COMPARATOR","Advanced Cardiac Life Support (ACLS) as per the hospitals standard protocol, including advanced interventions such as extended cardio-pulmonary resuscitation (eCPR).",[13],"Other: Advanced Cardiac Life Support (ACLS)",{"label":15,"type":16,"description":17,"interventionNames":18},"Advanced Cardiac Life Support (ACLS) plus REBOA","EXPERIMENTAL","Advanced Cardiac Life Support (ACLS) as per the hospitals standard protocol, including advanced interventions such as eCPR plus resuscitative balloon occlusion of the descending thoracic aorta (REBOA).",[19,13],"Device: resuscitative endovascular occlusion of the aorta (REBOA)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","resuscitative endovascular occlusion of the aorta (REBOA)","Insertion of a balloon catheter through the common femoral artery, retrograde advancement of the catheter into the descending thoracic aorta, ballon occlusion of the aorta",[15],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Advanced Cardiac Life Support (ACLS)","Advanced Cardiac Life Support (ACLS) as per American Heart Association (AHA) or European Resuscitation Council (ERC) standards",[9,15],[32],{"name":33,"affiliation":34,"role":35},"Wolf E Hautz, MD, MME","Inselspital University Hospital Bern","PRINCIPAL_INVESTIGATOR",[37,41],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","+41 31 632 57 01","wolf.hautz@insel.ch",{"name":42,"role":38,"phone":39,"phoneExt":26,"email":43},"Cornelia Lammbrigger, RN","ukn.studynurse@insel.ch",[45],{"facility":34,"status":46,"city":47,"state":26,"zip":48,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"RECRUITING","Bern","3010","Switzerland","CH",{"type":52,"coordinates":53},"Point",[54,55],7.44744,46.94809,{"lat":55,"lon":54},[58],{"name":59,"role":38,"phone":60,"phoneExt":26,"email":43},"Wolf E Hautz, MD","41316325701",{"type":62,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR","100626368","in-hospital-cardiopulmonary-resuscitation-with-balloon-occlusion-of-the-descending-aorta-100626368",false,"NCT07434726","In-hospital Cardiopulmonary Resuscitation With Balloon Occlusion of the Descending Aorta","CPReboa: In-hospital Cardiopulmonary Resuscitation With Balloon Occlusion of the Descending Aorta","CPReboa","Inclusion criteria:\n\n* patients suffering from in hospital cardiac arrest (IHCA), including patients with out of hospital cardiac arrest (OHCA) and return of spontaneous circulation (ROSC), transported to the emergency department, where they suffer a second arrest (IHCA)\n* successful placement of a femoral artery introducer sheath\n* any electrical cardiac activity seen in the initial rhythm analysis\n* ongoing effort of resuscitation as determined by study-independent resuscitation lead\n\nExclusion criteria:\n\n* IHCA in the operating room, on intensive care unit or in the cardiac catheter laboratory\n* hospital visitors suffering from cardiac arrest\n* asystole seen in the initial rhythm analysis\n* (presumed) age under 18 years\n* known \"do not resuscitate\"-order\n* known or obvious pregnancy\n* traumatic cardiac arrest\n* known aortic pathologies that render cannulation impossible\n* known allergies to radiographic contrast agents","ALL","18 Years",{"count":74,"type":75},98,"ESTIMATED","INTERVENTIONAL",[78],"NA","This study will test if a sustained Return of Spontaneous Circulation (ROSC) in patients with cardiac arrest is more frequent when patients receive advanced cardiac life support (ACLS) alone or when they receive ACLS plus a balloon occlusion of the thoracic aorta.",[81],"Cardiac Arrest",[81,83,84,85],"resuscitative endovascular occlusion of the aorta REBOA","cardio pulmonary resuscitation CPR","advanced cardiac life support ACLS","2026-04-20",{"date":88,"type":89},"2026-04-23","ACTUAL",{"date":91,"type":89},"2026-04-14",{"date":93,"type":75},"2030-12",{"name":5,"class":6},1]