[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100462414":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":28,"locations":33,"responsibleParty":52,"collaborators":20,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":20,"eligibilityCriteria":59,"healthyVolunteers":56,"sex":60,"minAge":61,"maxAge":20,"enrollmentInfo":62,"targetDuration":20,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":20,"overallStatus":36,"whyStopped":20,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"University of Arkansas","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Procedure","EXPERIMENTAL","Subjects will receive PAFC procedure",[13],"Device: Photoacoustic Flow Cytometry",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Photoacoustic Flow Cytometry","Detection of circulating blood clots",[9],null,[22,25],{"name":23,"affiliation":5,"role":24},"Sanjeeva Onteddu, MD","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":5,"role":27},"Jonathan A Young","STUDY_DIRECTOR",[29],{"name":23,"role":30,"phone":31,"phoneExt":20,"email":32},"CONTACT","5016865135","sronteddu@uams.edu",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Univerisity of Arkansas for Medical Sciences","RECRUITING","Little Rock","Arkansas","72205","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-92.28959,34.74648,{"lat":46,"lon":45},[49],{"name":50,"role":30,"phone":51,"phoneExt":20,"email":32},"Sanjeeva Onteddu, M.D.","501-686-5135",{"type":53,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100462414","in-vivo-detection-of-circulating-clots-in-patients-with-thromboembolism-100462414",false,"NCT05301348","In Vivo Detection of Circulating Clots in Patients With Thromboembolism","Inclusion Criteria\n\n* Men and women, 18 years old and older.\n* Evidence of current venous or arterial thromboembolic disease diagnosed by standard of care clinical, radiographic, or laboratory testing or acute ischemic stroke.\n* Informed consent provided by the subject.\n\nExclusion Criteria\n\n* Pulmonary embolus with a need for mechanical ventilation or other ventilator support (may be on oxygen delivered by nasal cannula or mask at an FiO2 of ≤ 0.40)\n* Acute coronary syndrome (including unstable angina)\n* Significant cardiac arrhythmia (may have atrial fibrillation controlled with medication)\n* Intracardiac thrombus\n* Any embolus or thrombus requiring vascular surgery or interventional radiology to attempt acute embolectomy or thrombectomy\n* Sickle cell disease with vaso-occlusive crisis\n* Sepsis or life-threatening infection\n* Traumatic injury requiring hospitalization (within 30 days prior to enrollment)\n* Pregnancy or breastfeeding\n* Severe mental illness\n* Other conditions deemed by the investigators to put the subject at greater risk","ALL","18 Years",{"count":63,"type":64},30,"ESTIMATED","INTERVENTIONAL",[67],"NA","Subjects with thromboembolic disease or at high-risk for thromboembolic conditions diagnosed with ultrasound or other standard of care techniques will be recruited to estimate the feasibility of a device to detect in vivo CBCs.",[70],"Thromboembolism","2026-02-18",{"date":73,"type":74},"2026-02-19","ACTUAL",{"date":76,"type":74},"2023-07-26",{"date":78,"type":64},"2027-01-31",{"name":5,"class":6},1]