[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566012":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":15,"locations":7,"responsibleParty":25,"collaborators":7,"id":29,"slug":30,"hasResults":31,"nctId":32,"briefTitle":33,"officialTitle":33,"acronym":7,"eligibilityCriteria":34,"healthyVolunteers":35,"sex":36,"minAge":7,"maxAge":37,"enrollmentInfo":38,"targetDuration":7,"studyType":41,"phases":7,"briefSummary":42,"conditions":43,"keywords":7,"overallStatus":45,"whyStopped":7,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":7},{"fullName":5,"class":6},"Assiut University","OTHER",null,[9,13],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Inborn errors of immunity","A. Routine\n\n.1CBC with blood film.\n\n.2Liver Function Test.\n\n.3Kidney Function Test.\n\n4\\. Inflamatory marker ESR, CRP\n\nB.Immunology\n\n1. Immunoglobulins IgG, IgM, IgA, IgE\n2. Flow cytometric assessment: B Cell (CD19), T cells (CD3,CD4, CD8) anc NK Cells (CD16+56) and other markers whenever needed (e.g. CD40, CD40L for cases of hyper IGM)\n3. Chest x-ray to assess thymus and any abnormality\n4. DHR123 whenever needed (e.g. chronic granulomatous disease).\n5. LAD panel (CD11b CD15-CD18) whenever needed.\n\n6\\. Complement assay (CH",{"type":10,"name":14,"description":12,"armGroupLabels":7,"otherNames":7},"A. Routine .1CBC with blood film. .2Liver Function Test. .3Kidney Function Test. 4. Inflamatory marker ESR, CRP B.Immunology 1-Immunoglobulins IgG, IgM, IgA, IgE 2-Flow cytometric assessment: B",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":19,"email":20},"Christeena Goda Hakeem, Resident of Pediatrics","CONTACT","01271711547","madonaj985@gmail.com",{"name":22,"role":18,"phone":23,"phoneExt":7,"email":24},"Ismail Lotfy Mohamad, Professor of Pediatrics","01063398967","ismail231@aun.edu.eg",{"type":26,"investigatorFullName":27,"investigatorTitle":28,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Christeena Goda Hakeem","Inbon errors of immunity attending Assiut University Children's Hospital: a single center study","100566012","inbon-errors-of-immunity-attending-assiut-university-childrenamp39s-hospital-a-single-center-study-100566012",false,"NCT06649643","Inbon Errors of Immunity Attending Assiut University Children&Amp;#39;s Hospital: a Single Center Study","Inclusion Criteria:patients with the ten warning signs are four or more new ear\n\ninfections within 1 year,two or more serious sinus infections within 1 year,two or more months on antibiotics with little effect,two or more pneumonias within 1 year,failure of an infant to gain weight or grow normally,recurrent, deep skin or organ abscesses, persistent thrush in mouth or fungal infection on skin, need for intravenous antibiotics to clear infections,Two or more deep-seated infections including septicemia and family history of IEIs -\n\nExclusion Criteria:\n\n* patients without any criteria of ten warning signs",true,"ALL","18 Years",{"count":39,"type":40},60,"ESTIMATED","OBSERVATIONAL","Aim of Study The aim of this study to describe the clinical profile of children diagnosed as IEIs who were admitted to in Assiut university children\\'s Hospital.",[44],"Primary Immunodeficiency Diseases (PID)","NOT_YET_RECRUITING","2024-10-18",{"date":48,"type":49},"2024-10-21","ACTUAL",{"date":51,"type":40},"2025-01-05",{"date":53,"type":40},"2026-03-05",{"name":5,"class":6}]