[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617371":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":19,"locations":10,"responsibleParty":25,"collaborators":10,"id":27,"slug":28,"hasResults":29,"nctId":30,"briefTitle":31,"officialTitle":32,"acronym":33,"eligibilityCriteria":34,"healthyVolunteers":29,"sex":35,"minAge":36,"maxAge":10,"enrollmentInfo":37,"targetDuration":10,"studyType":40,"phases":10,"briefSummary":41,"conditions":42,"keywords":51,"overallStatus":59,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":10},{"fullName":5,"class":6},"Azienda Sanitaria Locale CN2 Alba-Bra","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Non-Metastatic Breast Cancer Patients Receiving Chemotherapy",null,"This group includes male and female participants diagnosed with non-metastatic breast cancer who are receiving neoadjuvant or adjuvant chemotherapy according to standard clinical practice. All participants are treated at the Oncology Unit of Michele and Pietro Ferrero Hospital in Verduno. Eligible participants are those for whom chemotherapy is indicated as part of routine care and who are willing and able to complete sensory tests, nutritional assessments, and quality-of-life questionnaires during the study period.",[13],"Other: Taste Assessment \u002F Nutritional Assessment \u002F Quality of Life Assessment",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"Taste Assessment \u002F Nutritional Assessment \u002F Quality of Life Assessment","Participants will undergo additional procedures as part of the study to assess taste function, nutritional status, and quality of life. These procedures include:\n\n* Taste assessment using standardized taste strips to measure recognition thresholds for the five basic tastes (sweet, sour, salty, bitter, umami) and chemesthetic sensitivity using strips impregnated with capsaicin.\n* Questionnaires to evaluate chemotherapy-induced taste alterations (CiTAS) and general quality of life (FACT-G).\n* Nutritional assessment, including evaluation of caloric and macronutrient intake using 24-hour dietary recalls, assessment of nutritional status according to GLIM criteria, and measurement of phase angle through bioelectrical impedance analysis (BIA).\n\nAll procedures are non-invasive and performed in addition to the participants' standard chemotherapy treatment.",[9],[20],{"name":21,"role":22,"phone":23,"phoneExt":10,"email":24},"Cloè Dalla Costa, MD","CONTACT","+39.0172.1408493","cdallacosta@aslcn2.it",{"type":26,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100617371","incidence-of-dysgeusia-in-breast-cancer-patients-undergoing-chemotherapy-100617371",false,"NCT07317752","Incidence of Dysgeusia in Breast Cancer Patients Undergoing Chemotherapy","Incidenza Della Disgeusia Nei Pazienti Affetti da Carcinoma Mammario in Trattamento Chemioterapico: Uno Studio Pilota Prospettico","GustiAmo","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Diagnosis of non-metastatic breast cancer\n* Indication for neoadjuvant or adjuvant chemotherapy as part of standard clinical practice\n* Chemotherapy-naïve patients (no chemotherapy received in the previous 12 months)\n* Signed written informed consent\n\nExclusion Criteria:\n\n* Terminal or metastatic disease\n* Pre-existing taste or smell disorders (e.g., anosmia, dysgeusia, neurological syndromes, etc.)\n* Known allergies to any substances used in taste and chemesthetic function tests (e.g., quinine dihydrochloride, monosodium L-glutamate, capsaicin, etc.)\n* Receiving neoadjuvant or adjuvant chemotherapy within research protocols\n* Lack of signed written informed consent","ALL","18 Years",{"count":38,"type":39},40,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to examine how frequently changes in taste occur in people with early-stage breast cancer who receive chemotherapy. It will also look at how these taste changes affect nutrition and quality of life. The main questions this study aims to answer are:\n\n* How many participants develop changes in taste during chemotherapy?\n* How do these changes affect eating habits, nutrition, and daily life?\n\nParticipants are women with non-metastatic breast cancer who are receiving chemotherapy before or after surgery.\n\nResearchers will use standardized taste tests to measure how well participants can perceive different flavors. These tests are designed to provide accurate and reproducible results.\n\nParticipants will:\n\n* Take part in taste tests during their chemotherapy treatment\n* Have their nutritional status evaluated\n* Answer questions about their quality of life",[43,44,45,46,47,48,49,50],"Taste Disorders","Breast Cancer","Quality of Life","Taste Perception","Dysgeusia","Chemotherapy Effects","Nutritional Status","Sensory Testing",[47,52,53,54,55,56,57,58],"Taste disorders","Breast cancer","Quality of life","Taste perception","Chemotherapy effects","Nutritional status","Sensory testing","NOT_YET_RECRUITING","2025-12-24",{"date":62,"type":63},"2026-01-05","ACTUAL",{"date":65,"type":39},"2026-01",{"date":67,"type":39},"2027-12",{"name":5,"class":6}]