[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100381912":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":23,"locations":34,"responsibleParty":49,"collaborators":17,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":17,"enrollmentInfo":60,"targetDuration":17,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":70,"overallStatus":37,"whyStopped":17,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Assistance Publique - Hôpitaux de Paris","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Exhaustive exploration","Exhaustive exploration of newly diagnosed COPD patients (pulmonary pathology and associated comorbidities)",[12],"Other: Exhaustive exploration",[14],{"type":6,"name":9,"description":15,"armGroupLabels":16,"otherNames":17},"* clinical investigations\n* imagery\n* blood assessment\n* functional respiratory investigations\n* muscle function \u002F skeletal muscle index",[9],null,[19],{"name":20,"affiliation":21,"role":22},"Laurent BOYER, MD","Assistance Publique Hôpitaux de Paris (AP-HP)","PRINCIPAL_INVESTIGATOR",[24,29],{"name":20,"role":25,"phone":26,"phoneExt":27,"email":28},"CONTACT","(0) 1 49 81 26 90","+ 33","laurent.boyer@aphp.fr",{"name":30,"role":25,"phone":31,"phoneExt":32,"email":33},"Lila KACI","(0) 1 49 81 36 24","+33","lila.kaci@aphp.fr",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":17},"Hopital Henri MONDOR","RECRUITING","Créteil","Île-de-France Region","94000","France","FR",{"type":44,"coordinates":45},"Point",[46,47],2.46569,48.79266,{"lat":47,"lon":46},{"type":50,"investigatorFullName":17,"investigatorTitle":17,"investigatorAffiliation":17,"oldNameTitle":17,"oldOrganization":17},"SPONSOR","100381912","incident-chronic-obstructive-pulmonary-disease-cohort-study-iconic-100381912",false,"NCT04252781","Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)","ICONIC","Inclusion Criteria:\n\nInclusion criteria of smokers with spirometry (pre-inclusion)\n\n* Age\\> 35 years\n* Smoking \\> 20 PA\n* Active smoking (cessation \\\u003C 1 month)\n* Signature of consent to participate in Phase I of the study\n\nInclusion criteria for patients with incidental COPD\n\n* FEV1 \u002F FVC \\\u003C70% of the theoretical value and \u002F or \\\u003CLLN (Lower limit of normal)\n* Signature of consent to participate in Phase II of the study\n\nExclusion Criteria:\n\n* Known COPD\n* Cancer being treated\n* No affiliation to the social security or other social protection scheme\n* Pregnant or lactating woman\n* Patient deprived of liberty or under legal protection (under tutorship or curatorship","ALL","35 Years",{"count":61,"type":62},300,"ESTIMATED","INTERVENTIONAL",[65],"NA","Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs. The impact on the health system of undiagnosed patients, up to 70% of patients, is increasingly documented. However, systematic spirometry screening remains controversial among smokers in the absence of data to link the detection of new patients with improved management and clinical events and health goals. More generally, there is little data on the evolution of patients in real life once they have entered the care system.\n\nThe premise is that with systematic screening in general medicine, it is possible to identify the evolution of newly diagnosed COPD patients, to distinguish the different possible evolutions according to the initial phenotype and the management.",[68,69],"Smokers","Chronic Obstructive Pulmonary Disease",[71,72,73],"Incident Chronic Obstructive Pulmonary Disease","comorbidities","trajectories","2025-01-07",{"date":76,"type":77},"2025-01-09","ACTUAL",{"date":79,"type":77},"2020-08-20",{"date":81,"type":62},"2026-02-20",{"name":5,"class":6},1]