[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100495043":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":44,"centralContacts":52,"locations":61,"responsibleParty":78,"collaborators":35,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":35,"eligibilityCriteria":86,"healthyVolunteers":82,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":35,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":99,"overallStatus":64,"whyStopped":35,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Central Institute of Mental Health, Mannheim","OTHER",[8,14,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"HIIT morning","ACTIVE_COMPARATOR","High-intensity interval training (HIIT) in the morning",[13],"Behavioral: Standard smoking cessation program (SCP)",{"label":15,"type":16,"description":17,"interventionNames":18},"HIIT evening","EXPERIMENTAL","High-intensity interval training (HIIT) in the evening",[13,19],"Behavioral: High-intensity interval training (HIIT evening)",{"label":21,"type":10,"description":22,"interventionNames":23},"HIIT morning + CRT","High-intensity interval training (HIIT) in the morning + cognitive remediation treatment (CRT)",[13,24],"Behavioral: Cognitive remediation treatment (CRT)",{"label":26,"type":16,"description":27,"interventionNames":28},"HIIT evening + CRT","High-intensity interval training (HIIT) in the evening+ cognitive remediation treatment (CRT)",[13,24,19],[30,36,40],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"BEHAVIORAL","Standard smoking cessation program (SCP)","Each subject will receive a standard SCP as group treatment once a week (1h) over six weeks. This group therapy is based on behavioural therapy and a psycho-educational approach (for more details see Batra \\& Buchkremer, 2004), and will be carried out by a qualified therapist.",[15,26,9,21],null,{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Cognitive remediation treatment (CRT)","The cognitive remediation treatment (CRT) employs a chess-based battery of tasks (delivered through an app-based online tool), two times per week over six weeks (60min duration per session).",[26,21],{"type":31,"name":41,"description":42,"armGroupLabels":43,"otherNames":35},"High-intensity interval training (HIIT evening)","The high-intensity interval training will be delivered through an app environment with several choices of exercise, two times per week over six weeks.\n\nThe training will include a 5-minutes warm-up and cool down phase. In between, participants will perform four 4-minutes blocks of exercise at high intensity, interspersed with three 3-minute blocks of low intensity (total of 35 minutes exercise).",[15,26],[45,48,50],{"name":46,"affiliation":5,"role":47},"Sabine Vollstädt-Klein, Prof. Dr.","PRINCIPAL_INVESTIGATOR",{"name":49,"affiliation":5,"role":47},"Gordon Feld, Dr.",{"name":51,"affiliation":5,"role":47},"Karen Ersche, Prof. Dr.",[53,58],{"name":46,"role":54,"phone":55,"phoneExt":56,"email":57},"CONTACT","+49-621\u002F1703","3912","s.vollstaedt-klein@zi-mannheim.de",{"name":49,"role":54,"phone":55,"phoneExt":59,"email":60},"6540","gordon.feld@zi-mannheim.de",[62],{"facility":63,"status":64,"city":65,"state":66,"zip":67,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":75,"contacts":76},"Klinik für Abhängiges Verhalten, Zentralinstitut für Seelische Gesundheit","RECRUITING","Mannheim","Baden-Wurttemberg","68159","Germany","DE",{"type":71,"coordinates":72},"Point",[73,74],8.46694,49.4891,{"lat":74,"lon":73},[77],{"name":46,"role":54,"phone":35,"phoneExt":35,"email":57},{"type":79,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR","100495043","increasing-smoking-cessation-success-through-sleep-amplified-memory-consolidation-100495043",false,"NCT05726045","Increasing Smoking Cessation Success Through Sleep-amplified Memory Consolidation","Increasing the Smoking Cessation Success Rate by Enhancing Improvement of Self-control Through Sleep-amplified Memory Consolidation","Inclusion Criteria:\n\n* severe tobacco use disorder (TUD) according to DSM-5\n* sufficient ability to communicate with investigators and answer questions in both written and verbal format\n* ability to provide fully informed consent and to use self-rating scales\n* right-handedness\n* HIIT can be performed without the risk of side effect (medical sports check)\n\nExclusion Criteria:\n\n* severe internal, neurological, and\u002For psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for mild depression, i.e. F32.0, adjustment disorder and specific phobias) in the last 12 months\n* history of brain injury\n* severe physical diseases\n* common exclusion criteria for MRI (e.g. metal, claustrophobia)\n* positive drug screening (opioids, benzodiazepines, barbiturates, cocaine, amphetamines)\n* psychotropic medication within the last 14 days\n* pregnancy","ALL","18 Years","65 Years",{"count":91,"type":92},140,"ESTIMATED","INTERVENTIONAL",[95],"NA","The goal of this subproject is to examine the hypothesized improvement of treatment with chess-based training and sleep enhancement, both together and on their own, in smokers.\n\nParticipants will undergo fMRI measurements, sleep monitoring. They will then be assigned to one of the four experimental groups, including high-intensity interval training with or without chess-based training.",[98],"Tobacco Use Disorder",[100,101,102,103,104,105],"Addiction","Nicotine","Smoking Cessation","Relapse","Cognitive remediation","Exercise training","2025-01-29",{"date":108,"type":109},"2025-01-31","ACTUAL",{"date":111,"type":109},"2024-04-01",{"date":113,"type":92},"2026-06-30",{"name":5,"class":6},1]