[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643987":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":30,"centralContacts":35,"locations":41,"responsibleParty":61,"collaborators":30,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":30,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":88,"overallStatus":44,"whyStopped":30,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of British Columbia","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Sulforaphane Supplementation Only","EXPERIMENTAL","In this intervention, participants will consume commercially available broccoli sprout extract capsules daily for 4 days (20 mg\u002Fday) . Basic anthropometrics (weight, heart rate, blood pressure) and a venous blood sample (30 mL) will be collected before and after this interventional period.",[13],"Dietary Supplement: Sulforaphane-rich Broccoli Sprout Extract",{"label":15,"type":16,"description":17,"interventionNames":18},"Exercise Only","ACTIVE_COMPARATOR","In this intervention, participants will complete supervised exercise sessions daily for 4 days. The exercise intervention consists of interval running on a treadmill which contains 4 cycles of: 4 minutes of intense running (85-95% HRmax) followed by 3 minutes at a slow, easy pace. Basic anthropometrics (weight, heart rate, blood pressure) and a venous blood sample (30 mL) will be collected before and after this interventional period.",[19],"Other: High Intensity Interval Treadmill Running",{"label":21,"type":10,"description":22,"interventionNames":23},"Sulforaphane Supplementation and Exercise","In this intervention, participants will consume commercially available broccoli sprout extract tablets daily for 4 days. In addition, participants will complete supervised exercise sessions daily for 4 days. The exercise intervention consists of interval running on a treadmill which contains 4 cycles of: 4 minutes of intense running (85-95% HRmax) followed by 3 minutes at a slow, easy pace. Basic anthropometrics (weight, heart rate, blood pressure) and a venous blood sample (30 mL) will be collected before and after this interventional period.",[13,19],[25,31],{"type":26,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"DIETARY_SUPPLEMENT","Sulforaphane-rich Broccoli Sprout Extract","Broc Elite Plus stabilized sulforaphane capsules from Mara Labs",[9,21],null,{"type":6,"name":32,"description":33,"armGroupLabels":34,"otherNames":30},"High Intensity Interval Treadmill Running","4 cycles of: 4 minutes of intense treadmill running (85-95% HR max) followed by 3 minutes of slow, easy running.",[15,21],[36],{"name":37,"role":38,"phone":39,"phoneExt":30,"email":40},"Hashim Islam Principle Investigator, Ph.D","CONTACT","250-807-9122","hashim.islam@ubc.ca",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Reichwald Health Sciences Centre","RECRUITING","Kelowna","British Columbia","V1V 1V7","Canada","CA",{"type":51,"coordinates":52},"Point",[53,54],-119.48568,49.88307,{"lat":54,"lon":53},[57],{"name":58,"role":38,"phone":59,"phoneExt":30,"email":60},"Sean McIntyre","2505757528","smcint04@student.ubc.ca",{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Hashim Islam","Assistant Professor","100643987","independent-and-combined-effects-of-short-term-sulforaphane-supplementation-and-exercise-on-immunometabolism-in-healthy-adults-100643987",false,"NCT07668596","Independent and Combined Effects of Short-term Sulforaphane Supplementation and Exercise on Immunometabolism in Healthy Adults","Independent and Combined Effects of Short-term Sulforaphane Supplementation and Exercise on Immunometabolism in Healthy Adults: A Randomized Crossover Study","EXSFN","Inclusion Criteria:\n\n* aged between 18 and 35 years\n* not a current smoker\n* physically active based on the Canadian Physical Activity Guidelines (150 minutes of weekly physical activity)\n\nExclusion Criteria:\n\n* a history of cardiometabolic diseases or respiratory diseases (e.g., chronic obstructive pulmonary disease, asthma, diabetes, coronary artery disease)\n* currently following a ketogenic diet\n* body mass index (BMI) over 30 kg\u002Fm2\n* unable to read or communicate in English\n* having received a vaccination or experienced an upper respiratory tract infection in the last 4 weeks\n* having donated more than 0.5 L of blood within the last 4 weeks\n* currently pregnant\n* have contraindications to high intensity exercise (assessed using the CSEP Get Active Questionnaire)",true,"ALL","19 Years","35 Years",{"count":78,"type":79},20,"ESTIMATED","INTERVENTIONAL",[82],"NA","The study consist of 3 interventional periods which will be completed by each consenting participant in a randomized, crossover fashion. The interventional periods will be separated by a minimum 1 week washout period. One of the interventions consists of 4 days of daily supplementation with the commercially available broccoli sprout extract capsules (BrocElite). Another intervention will consist of 4 days of daily supervised treadmill running. The exercise protocol consists of 4 minutes of high-intensity running running followed by a 3 minute recovery period, repeated for a total of 4 repetitions. The last intervention combines the above two and consists of 4 days of daily supplementation and daily supervised exercise training. Before and after each intervention, basic anthropometrics (weight, heart rate, and blood pressure) will be recorded, and a venous blood sample will be collected. Blood samples will be analyzed for metabolic and inflammatory markers. Participants will be asked to refrain from structured exercise, alcohol consumption, and broccoli consumption during each of the experimental periods. Before any testing, willing participants will provide informed consent, and fill out a few demographic, and lifestyle questionnaires. The study will be conducted at the University of British Columbia in Kelowna, BC, Canada.",[85,86,87],"Immunometabolism","Mitochondrial Function, Bioenergetics","Inflammation",[89,90,91,85,87,92],"Nutraceuticals","Exercise","Bioenergetics","High intensity interval training","2026-06-19",{"date":95,"type":96},"2026-06-25","ACTUAL",{"date":98,"type":96},"2026-03-01",{"date":100,"type":79},"2028-06-01",{"name":5,"class":6},1]