[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100628528":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":10,"centralContacts":20,"locations":30,"responsibleParty":46,"collaborators":10,"id":50,"slug":51,"hasResults":52,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":52,"sex":58,"minAge":10,"maxAge":10,"enrollmentInfo":59,"targetDuration":10,"studyType":62,"phases":10,"briefSummary":63,"conditions":64,"keywords":66,"overallStatus":74,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Critically ill children with weight under 10 kilograms undergoing indirect calorimetry",null,"This cohort includes critically ill children weighing less than 10 kilograms who are admitted to a pediatric intensive care unit. Participants undergo indirect calorimetry measurements using the Q-NRG+ device in addition to standard clinical care. Measured energy expenditure is recorded and analyzed without altering routine treatment.",[13],"Device: Q-NRG+",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Q-NRG+","The Q-NRG+ is an indirect calorimetry device used to measure resting energy expenditure in mechanically ventilated or spontaneously breathing patients. In this study, the device is connected to the ventilator circuit or used with a canopy hood to measure oxygen consumption and carbon dioxide production for calculation of energy expenditure. Measurements are performed in addition to standard clinical care and do not alter routine treatment.",[9],[21,26],{"name":22,"role":23,"phone":24,"phoneExt":10,"email":25},"Mirjam Larsson, Ass Senior Consultant PhD stud","CONTACT","+46707474628","mirjam.m.larsson@regionstockholm.se",{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},"Urban Fläring, Ass prof, senior consultant","+46708763900","urban.flaring@ki.se",[31],{"facility":32,"status":10,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Pediatric Perioperative Medicine and Intensive Care Stockholm, Sweden","Stockholm","Solna","17176","Sweden","SE",{"type":39,"coordinates":40},"Point",[41,42],18.06871,59.32938,{"lat":42,"lon":41},[45],{"name":27,"role":23,"phone":28,"phoneExt":10,"email":29},{"type":47,"investigatorFullName":48,"investigatorTitle":49,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Urban Fläring","Associated professor","100628528","indirect-calorimetry-measurement-in-the-pediatric-intensive-care-units-smallest-patients-100628528",false,"NCT07462806","Indirect Calorimetry Measurement in the Pediatric Intensive Care Unit's Smallest Patients","Indirect Calorimetry Measurement in the Paediatric Intensive Care Unit's Smallest Patients","Q-NRG2025","Inclusion Criteria: Newborns and infants admitted to the PICU with body weight from 0,5 up to 10 kilograms. Either requiring mechanically ventilation, with FiO2 \\\u003C 70%, PIP\\\u003C30 cmH2O and no leakage in the ventilation system. Or spontaneous breathing patients tolerating measurements with canopy.\n\nExclusion Criteria:\n\nIn mechanically ventilated patients' unstable ventilation including ventilation settings changed during the last 60 minutes (FiO2 \\>70%, PIP\\>30 cmH2O, or ventilation system leakage). Patients spontaneous breathing not tolerating measurements with canopy.","ALL",{"count":60,"type":61},80,"ESTIMATED","OBSERVATIONAL","Indirect calorimetry is considered the reference method for measuring energy expenditure in intensive care patients. However, in infants and small children weighing less than 10 kilograms, its clinical use has historically been limited due to technical challenges related to low tidal volumes, potential increases in dead space, and measurement precision.\n\nThe goal of this observational study is to evaluate the feasibility and performance of indirect calorimetry using the Q-NRG+ device in critically ill children weighing less than 10 kg who are admitted to a pediatric intensive care unit.",[65],"Pediatric Critical Illness",[65,67,68,69,70,17,71,72,73],"weight under 10 kilogram","Indirect calorimetry","Energy expenditure","Nutritional assessment","Pediatric intensive care","chofield equation","Metabolic monitoring","NOT_YET_RECRUITING","2026-03-05",{"date":77,"type":78},"2026-03-10","ACTUAL",{"date":80,"type":61},"2026-04",{"date":82,"type":61},"2027-12",{"name":5,"class":6},1]