[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643273":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":40,"responsibleParty":57,"collaborators":60,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":25,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":85,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Hugo W. Moser Research Institute at Kennedy Krieger, Inc.","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active stimulation combined with therapy.","EXPERIMENTAL","Once a stimulation site is determined, subjects will receive 20 minutes of active tDCS stimulation daily. Subjects will also receive one hour of therapy, twice daily. Therapy will be individualized to each subject and, will encompass three domains; 1) walking and balance control, 2) hand dexterity and arm control, 3)speech articulation, prosody, and intelligibility. Subjects will complete up to 30 therapy sessions.",[13],"Behavioral: Therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Sham stimulation combined with therapy.","SHAM_COMPARATOR","Once a stimulation site is determined, subjects will receive 20 minutes of sham tDCS stimulation daily. Subjects will also receive one hour of therapy, twice daily. Therapy will be individualized to each subject and, will encompass three domains; 1) walking and balance control, 2) hand dexterity and arm control, 3)speech articulation, prosody, and intelligibility. Subjects will complete up to 30 therapy sessions.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","Therapy","Each participant will choose a domain that they would like to focus on. Choices are: 1) walking and balance control, 2) hand dexterity and arm control, or 3) speech articulation, prosody, and intelligibility.",[9,15],null,[27],{"name":28,"affiliation":29,"role":30},"Amy J Bastian, PhD, PT","Motion Analysis Lab in the Kennedy Krieger Institute","PRINCIPAL_INVESTIGATOR",[32,37],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Derek J Eversley, BS","CONTACT","443-923-2716","eversley@kennedykrieger.org",{"name":38,"role":34,"phone":35,"phoneExt":25,"email":39},"Anthony J Gonzalez, BS","gonzalezan@kennedykrieger.org",[41],{"facility":29,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"RECRUITING","Baltimore","Maryland","21205","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-76.61219,39.29038,{"lat":52,"lon":51},[55,56],{"name":38,"role":34,"phone":35,"phoneExt":25,"email":39},{"name":28,"role":30,"phone":25,"phoneExt":25,"email":25},{"type":30,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Amy J. Bastian, Ph.D.","Professor of Neuroscience",[61],{"name":62,"class":6},"Once Upon a Time Foundation","100643273","individualized-neuro-modulation-paired-with-cerebellar-therapy-100643273",false,"NCT07642856","Individualized Neuro-Modulation Paired With Cerebellar Therapy","IMPACT","Inclusion Criteria:\n\n* Age 18-75 years\n* Males and Females\n* Disorders that predominantly affect the cerebellum: damage from stroke, tumor or degeneration (genetic or non-genetic causes, congenital hypoplasia).\n\nExclusion Criteria:\n\n* Diagnoses or impairments that interfere with task execution or data interpretation.\n* Heart pacemaker or other MRI-incompatible implanted metal device\n* Metallic foreign body in their eye or head\n* Experience with severe claustrophobia\n* Experience discomfort from the MRI scan, such as excessive heating of tattoos\n* Seizures or history of seizure disorder\n* Alcohol or substance use disorder (self-report)\n* Diagnosed history of severe psychiatric disorder such as depression, schizophrenia (self-report)\n* Metallic foreign body in their eye or head (except the mouth e.g. dental fillings)\n* Specific medications: tricyclic anti-depressants or neuroleptic medication\n* Any medical condition (including orthopedic, pain, cardiopulmonary or other) that limits safe participation in exercise training","ALL","18 Years","75 Years",{"count":74,"type":75},30,"ESTIMATED","INTERVENTIONAL",[78],"NA","The purpose of this project is to evaluate feasibility and preliminary efficacy of pairing personalized transcranial direct current stimulation (tDCS) with individualized rehabilitation therapy in people with cerebellar damage.",[81,82,83,84],"Cerebellar Ataxia","Cerebellar Diseases","Cerebellar Stroke","Cerebellar Tumor",[86,87,88],"non-invasive brain stimulation","rehabilitation","physical therapy","2026-06-08",{"date":91,"type":92},"2026-06-11","ACTUAL",{"date":94,"type":75},"2026-06-30",{"date":96,"type":75},"2032-12-02",{"name":5,"class":6},1]