[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100644879":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":24,"locations":34,"responsibleParty":55,"collaborators":10,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":67,"sex":68,"minAge":69,"maxAge":70,"enrollmentInfo":71,"targetDuration":10,"studyType":74,"phases":10,"briefSummary":75,"conditions":76,"keywords":10,"overallStatus":78,"whyStopped":10,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"South Valley University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"group A: systemic lupus erythrematosus",null,"about 20 patients diagnosed with SLE based on 2019 EULAR\u002FACR.",{"label":13,"type":10,"description":14,"interventionNames":10},"group B:healthy controls","10 with no personal or family history of autoimmune diseases or chronic inflammatory disorders.",[16,20],{"name":17,"affiliation":18,"role":19},"Eisa Mohammed Hegazy, Professor","Dermatology, Venereology & Andrology Department ,Faculty of Medicine ,South Valley University.","STUDY_CHAIR",{"name":21,"affiliation":22,"role":23},"Mohammed Hosny Hassan, Professor","Biochemistry , Qena faculty of medicine ,south valley university.","STUDY_DIRECTOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Dina Fetouh Abdel-latif, MSc","CONTACT","+201283364643","dedemoona@gmail.com",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Soheir abdel- Hamid Ali, lecturer","+201066877343","Soher.abdel-hamid@med.svu.edu.eg",[35],{"facility":36,"status":10,"city":37,"state":10,"zip":10,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"South Valley University Hospital","Qina","Egypt","EG",{"type":41,"coordinates":42},"Point",[43,44],32.72671,26.16418,{"lat":44,"lon":43},[47,51],{"name":48,"role":27,"phone":49,"phoneExt":10,"email":50},"Ebtehal Alaa El-din Kotp, lecturer","+201066798383","Ebtehal-alaa@med.svu.edu.eg",{"name":52,"role":27,"phone":53,"phoneExt":10,"email":54},"Shimaa Saber Ahmed, lecturer","+201006393764","shimaasaber063@gmail.com",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Dina Fetouh Abdel Latif","resident","100644879","inducible-co-stimulator-gene-with-systemic-lupus-erythematosus-100644879",false,"NCT07675837","Inducible Co-stimulator Gene With Systemic Lupus Erythematosus","Association of ICOS Gene Polymorphism With Susceptibility and Severity of Systemic Lupus Erythematosus.","ICOS\u002FSLE","Inclusion Criteria:\n\n* Patients diagnosed with SLE based on 2019 EULAR\u002FACR Male or female. willing to provide written informed consent for participation and genetic testing\n\nExclusion Criteria:\n\n* Other autoimmune diseases or chronic inflammatory disorders. Malignancy. Pregnancy or breastfeeding. Inability to provide informed consent.",true,"ALL","18 Years","65 Years",{"count":72,"type":73},30,"ESTIMATED","OBSERVATIONAL","The aim of this study is to investigate the association between ICOS gene polymorphism and susceptibility to systemic lupus erythematosus (SLE), as well as its impact on disease severity.",[77],"Systemic Lupus Erthematosus","NOT_YET_RECRUITING","2026-06-23",{"date":81,"type":82},"2026-06-30","ACTUAL",{"date":84,"type":73},"2026-06",{"date":86,"type":73},"2027-07",{"name":5,"class":6},1]