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Age between 18 and 80 years, no gender restrictions.\n2. Within 7 days of disease onset and expected NICU stay of at least 7 days.\n3. Eligible for enrollment within 24 hours of NICU admission, with enteral nutrition (EN) initiated and continued for at least 7 days.\n4. Non-traumatic severe brain injury patients (including cerebrovascular disease and encephalitis) with a Glasgow Coma Scale (GCS) score ≤12.\n5. NRS 2002 score ≥3.\n6. Kuwata drinking test ≥ grade 3.\n7. Acute Gastrointestinal Injury (AGI) grade 1 or 2.\n8. Signed informed consent obtained from the patient or their legal representative.\n\nExclusion Criteria:\n\n1. Severe malnutrition prior to admission, defined as BMI \\\u003C 16 kg\u002Fm².\n2. Pregnant or lactating women.\n3. Receiving hypothermia treatment or core body temperature \\\u003C 36°C.\n4. End-stage disease with an expected survival time of \\\u003C 48 hours, or severe dysfunction of the heart, lungs, or other vital organs, leading to hemodynamic instability.\n5. Malignant tumors.","ALL","18 Years","80 Years",{"count":315,"type":316},1185,"ESTIMATED","OBSERVATIONAL","The study aims to develop and validate a prognostic prediction model for adverse outcomes in neurocritical patients receiving enteral nutrition based on key inflammatory and metabolic markers. This model will serve as a clinical tool to help physicians identify high-risk patients and guide individualized nutritional support strategies.",[320,321,322],"Stroke Acute","Encephalitis","Non-traumatic Brain Injury",[324,325,326,327],"enteral nutrition","adverse prognosis","prediction model","non-traumatic severe brain injury","NOT_YET_RECRUITING","2025-02-23",{"date":331,"type":332},"2025-02-27","ACTUAL",{"date":334,"type":316},"2025-03-01",{"date":336,"type":316},"2027-03-31",{"name":58,"class":6},19]