[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100551742":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":15,"centralContacts":20,"locations":28,"responsibleParty":77,"collaborators":81,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":90,"sex":95,"minAge":96,"maxAge":97,"enrollmentInfo":98,"targetDuration":10,"studyType":101,"phases":10,"briefSummary":102,"conditions":103,"keywords":109,"overallStatus":31,"whyStopped":10,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Fundacin Biomedica Galicia Sur","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Premature Coronary Artery Disease",null,"Patients between 18 and 40 years old diagnosed with coronary artery disease, including: ST-elevation myocardial infarction (STEMI), non-ST-elevation acute coronary syndrome (NSTE-ACS), unstable angina, stable angina, MINOCA or silent angina",{"label":13,"type":10,"description":14,"interventionNames":10},"Non Coronary Artery Disease","Patient without coronary artery disease\n\nFor each case, 3 controls matched by age (±1 year), sex, postal code, and\u002For primary care center will be included. To avoid the selection of controls that could be associated with an overestimation of exposure to cardiovascular risk factors, the controls will be recruited from the preoperative unit and selected from subjects who have undergone minor clinical procedures (vasectomy, hernia repair, phimosis, prominent ear correction, tubal ligation, euthyroid thyroid nodule, plastic surgery, lipomas, vocal cord cysts, among others), or from the trauma service, selecting those attending for fractures or sprains. This approach ensures a complete medical history along with analytical values in their electronic medical records",[16],{"name":17,"affiliation":18,"role":19},"Pablo Juan-Salvadores, Pharma, PhD","Instituto de Investigación Sanitaria Galicia Sur (IIS Galicia Sur)","PRINCIPAL_INVESTIGATOR",[21,25],{"name":17,"role":22,"phone":23,"phoneExt":10,"email":24},"CONTACT","+34986825564","pablo.juan@iisgaliciasur.es",{"name":26,"role":22,"phone":23,"phoneExt":10,"email":27},"Victor A Jiménez-Diaz, MD, MPH","victor.alfonso.jimenez.diaz@sergas.es",[29],{"facility":30,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Hospital Álvaro Cunqueiro","RECRUITING","Vigo","Pontevedra","36211","Spain","ES",{"type":38,"coordinates":39},"Point",[40,41],-8.72264,42.23282,{"lat":41,"lon":40},[44,46,49,51,53,55,57,59,61,63,65,67,69,71,73,75],{"name":45,"role":22,"phone":23,"phoneExt":10,"email":24},"Pablo Juan Salvadores, MPH,PhD",{"name":47,"role":48,"phone":10,"phoneExt":10,"email":10},"Victor A Jiménez Díaz, MD","SUB_INVESTIGATOR",{"name":50,"role":19,"phone":10,"phoneExt":10,"email":10},"Andrés Iñiguez Romo, PhD",{"name":52,"role":48,"phone":10,"phoneExt":10,"email":10},"Samuel Pinos Rodriguez",{"name":54,"role":48,"phone":10,"phoneExt":10,"email":10},"Cesar Veiga Garcia, PhD",{"name":56,"role":48,"phone":10,"phoneExt":10,"email":10},"Susana Fernández Noceo",{"name":58,"role":48,"phone":10,"phoneExt":10,"email":10},"Ismael Said Criado, MD",{"name":60,"role":48,"phone":10,"phoneExt":10,"email":10},"Sara Blanco Dorado, PhD",{"name":62,"role":48,"phone":10,"phoneExt":10,"email":10},"Jose A Gonzalez Novoa",{"name":64,"role":48,"phone":10,"phoneExt":10,"email":10},"Laura Busto Castiñeira",{"name":66,"role":48,"phone":10,"phoneExt":10,"email":10},"Nuria Gallego Fernández, PhD",{"name":68,"role":48,"phone":10,"phoneExt":10,"email":10},"Ines Mato Naveira, PhD",{"name":70,"role":48,"phone":10,"phoneExt":10,"email":10},"Isaac Gomez Piñeiro, PhD",{"name":72,"role":48,"phone":10,"phoneExt":10,"email":10},"Silvia Campanioni Morfi",{"name":74,"role":48,"phone":10,"phoneExt":10,"email":10},"Blanca Trejo Velasco, PhD",{"name":76,"role":19,"phone":10,"phoneExt":10,"email":10},"Pablo Juan Salvadores, PhD",{"type":78,"investigatorFullName":79,"investigatorTitle":80,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","pablo Juan-Salvadores","Principal Investigator",[82,83,86],{"name":5,"class":6},{"name":84,"class":85},"Conselleria de Saúde Pública de Galicia","UNKNOWN",{"name":87,"class":85},"Conselleria de Medio Ambiente, Territorio e Vivenda de Galicia","100551742","influence-of-air-quality-on-the-development-and-progression-of-premature-coronary-artery-disease-100551742",false,"NCT06464042","Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease","AIRHEART","CASES:\n\nInclusion Criteria:\n\n* Women and men between 18 and 40 years old with a diagnosis of coronary artery disease coded in their medical records in Galicia\n\nExclusion Criteria:\n\n* Not having a postal code and primary care center assigned in their medical records in Galicia\n\nCONTROL\n\nInclusion Criteria:\n\n* Women and men between 18 and 40 years old with no diagnosis or history of CAD or other coronary disease coded in their medical records\n\nExclusion Criteria:\n\n* Present with non-ischemic coronary diseas.\n* Have a serious condition that affects or decreases life expectancy.\n* Do not have a postal code or primary care center assigned in their medical records in Galicia","ALL","18 Years","40 Years",{"count":99,"type":100},4272,"ESTIMATED","OBSERVATIONAL","The new global guidelines from the World Health Organization on air quality provide evidence of the damage that air pollution inflicts on human health at even lower concentrations than previously thought. Different studies have shown an increase in the incidence of coronary artery disease (CAD) in young people in recent decades. The main objective of this project is to study the impact of environmental pollutants on the premature manifestation of CAD from different epidemiological approaches and their impact on the evolution of these patients with a gender perspective. It is a retrospective analytical case-control study nested in a cohort of patients ≤40 years old with a clinical history of CAD including: ST-segment elevation myocardial infarction, non-ST-segment elevation acute coronary syndrome, unstable angina, stable angina or silent angina according to the international classification of diseases.",[104,105,106,107,108],"Coronary Artery Disease Premature","Angina, Stable","Acute Coronary Syndrome","MINOCA","Myocardial Infarction",[110,111,104],"Air pollution","young","2024-06-12",{"date":114,"type":115},"2024-06-18","ACTUAL",{"date":117,"type":115},"2024-05-23",{"date":119,"type":100},"2025-07-01",{"name":79,"class":6},1]