[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100495536":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":33,"collaborators":7,"id":35,"slug":36,"hasResults":37,"nctId":38,"briefTitle":39,"officialTitle":40,"acronym":7,"eligibilityCriteria":41,"healthyVolunteers":37,"sex":42,"minAge":43,"maxAge":7,"enrollmentInfo":44,"targetDuration":7,"studyType":47,"phases":7,"briefSummary":48,"conditions":49,"keywords":7,"overallStatus":17,"whyStopped":7,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},{"fullName":5,"class":6},"East Kent Hospitals University NHS Foundation Trust","OTHER_GOV",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Charlotte Burford","CONTACT","+44 1227 766877","charlotte.burford1@nhs.net",[15],{"facility":16,"status":17,"city":18,"state":19,"zip":20,"country":21,"countryCode":22,"cosmosGeoPoint":23,"geoPoint":28,"contacts":29},"EKHUFT","RECRUITING","Ashford","Kent","TN24 0LZ","United Kingdom","UK",{"type":24,"coordinates":25},"Point",[26,27],0.87376,51.14648,{"lat":27,"lon":26},[30],{"name":31,"role":11,"phone":12,"phoneExt":7,"email":32},"Ankur Shah","ankur.shah1@nhs.net",{"type":34,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100495536","influence-of-gut-microbiome-in-gallstone-disease-100495536",false,"NCT05732480","Influence of Gut Microbiome in Gallstone Disease","Understanding Changes in the Gut Microbiome in Patients With Gallstone Disease and Its Impact on Patient Outcomes","Inclusion Criteria:\n\n* All adults (age \\>18 years of age) patients diagnosed with gallstone disease following confirmatory imaging at an East Kent University Foundation Trust Hospital. Patients of any gender, ethnicity or socio-economic background are eligible as well as pregnant women. Patients undergoing both open and laparoscopic cholecystectomy will be included.\n\nExclusion Criteria:\n\n* Patients less than 18 years of age and patients who do not have capacity to consent to involvement in the study.","ALL","18 Years",{"count":45,"type":46},75,"ESTIMATED","OBSERVATIONAL","The goal of this prospective observational study is to explore the role of the gut microbiome in patients with gallstone disease.\n\nThe main question\\[s\\] it aims to answer are:\n\n* if there is a relationship between the gut microbiome and the development of complications associated with gallstone disease (such as pancreatitis and acute cholecystitis)\n* if there are changes in the gut microbiome following cholecystectomy and the relationship with patient outcomes.\n\nParticipants will be asked to provide stool samples at fixed time points (recruitment, pre- and post-cholecystectomy if applicable and at 6 months and 3 years. They will also be asked to provide stool samples if they represent to hospital with complications associated with their gallstone disease.",[50,51,52,53],"Gall Stone","Gall Stones, Common Bile Duct","Pancreatitis","Acute Cholecystitis","2024-02-22",{"date":56,"type":57},"2024-02-23","ACTUAL",{"date":59,"type":57},"2023-05-30",{"date":61,"type":46},"2026-11-13",{"name":5,"class":6},1]