[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100545096":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":26,"locations":36,"responsibleParty":54,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":25,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":83,"overallStatus":39,"whyStopped":25,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"Saint Petersburg State University, Russia","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Medical management based on results of ultrasound lungs examination","EXPERIMENTAL","Based on the degree\u002F presence of interstitial pulmonary edema (number of B-lines) and presence of postoperative pleural effusion, identified by regularly performed ultrasound examination of the lungs, medical therapy will be modified in each particular patient to improve clinical status and outcome. Administration of the following drug groups can be made\u002F doses can be adjusted: Diuretics (furosemide\u002F Hypothiazide\u002F spironolactone), Non-steroid antiinflammatory (Ibuprofen), Glucocorticoids.",[13],"Diagnostic Test: Ultrasound examination of the lungs",{"label":15,"type":16,"description":17,"interventionNames":18},"Medical management based on routine clinical and X-ray diagnostic methods","ACTIVE_COMPARATOR","Ultrasound examination of the lungs will be performed in all patients in this group, but the attending physician will not be informed about it's results and findings. Any changes in medical therapy\u002F treatment strategy will be based on standard clinical and X-ray diagnostic methods.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DIAGNOSTIC_TEST","Ultrasound examination of the lungs","Experimental: Standard ultrasound examination of the lungs based on modified BLUE protocol Active Comparator: Standard ultrasound examination of the lungs based on modified BLUE protocol",[9,15],null,[27,32],{"name":28,"role":29,"phone":30,"phoneExt":25,"email":31},"Aleksei A Filippov, MD, PhD","CONTACT","+79819553639","aleksei.filippov.chb@gmail.com",{"name":33,"role":29,"phone":34,"phoneExt":25,"email":35},"Sergey M Efremov, MD, PhD","+79137946090","sergefremov@mail.ru",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Saint Petersburg State University Clinic","RECRUITING","Saint Petersburg","Sankt-Peterburg","190020","Russia","RU",{"type":46,"coordinates":47},"Point",[48,49],30.31413,59.93863,{"lat":49,"lon":48},[52],{"name":53,"role":29,"phone":34,"phoneExt":25,"email":35},"Sergei M Efremov, MD, PhD",{"type":55,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Filippov Aleksei, MD, PhD","State Cardiovascular Surgeon","100545096","influence-of-lung-ultrasonography-on-the-prognosis-and-postoperative-outcomes-in-cardiac-surgical-patients-100545096",false,"NCT06377449","Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients","Influence of Ultrasound Examination of the Lungs on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients","Inclusion Criteria:\n\n* open heart surgery with cardiopulmonary bypass (CPB) between 15 December 2023 and 15 December 2024\n* signed informed consent for participation in the study\n\nExclusion Criteria:\n\n* reoperations on the open heart with CPB\n* surgical procedures on lungs and lung cancer in the anamnesis\n* chronic obstructive pulmonary disease, stage III\n* chronic kidney disease, stages 4 and 5\n* patients with low Risk Score profile by the Society of Thoracic Surgeons","ALL","18 Years",{"count":68,"type":69},186,"ESTIMATED","INTERVENTIONAL",[72],"NA","The goal of this interventional is to assess advantages of the ultrasound examination of the lungs in the early postoperative period in cardiac surgical patients after heart surgeries requiring cardiopulmonary bypass. Evaluation of pulmonary complications and outcomes during mid-term follow-up, as well as comparison of ultrasound examination and traditional roentgenologic methods (X-ray examination and CT of the chest) will be performed. The main question\\[s\\] it aims to answer are:\n\n* Is ultrasound examination of the lungs a more specific and sensitive method in identification of early postoperative pulmonary complications after on-pump cardiac surgical procedures, in comparison with traditional X-ray methods.\n* Does early identification of interstitial pulmonary edema (based on number of visualised B-lines in the early postoperative period), influences mid-term outcomes in this cohort of patients Participants will undergo ultrasound examination of the lungs on postoperative day 1, 3, 5 and 7 after heart surgery. Based on ultrasound findings and degree of interstitial pulmonary edema, medical (diuretics, anti-inflammatory, e.t.c) therapy will be modified.\n\nResearchers will compare this group of patients with control group, in which ultrasound examination will be performed in the same time frames, but no changes in medical management based on ultrasound findings will be made to see if timely administered medical therapy, based on ultrasound findings, can significantly improve symptoms, hospital lengths of stay and outcomes of this patients.",[75,76,77,78,79,80,81,82],"Ischemic Heart Disease","Aortic Stenosis, Severe","Aortic Insufficiency","Mitral Stenosis","Mitral Insufficiency","Mitral Stenosis With Insufficiency","Tricuspid Insufficiency","Ascending Aortic Aneurysm",[22,84,85,86,87,88],"B-lines","Coronary artery bypass grafting","Heart valve surgery","Cardiopulmonary bypass","On-pump cardiac surgery","2024-12-04",{"date":91,"type":92},"2024-12-09","ACTUAL",{"date":94,"type":92},"2024-05-15",{"date":96,"type":69},"2026-01-01",{"name":5,"class":6},1]