[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100611374":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":25,"responsibleParty":36,"collaborators":25,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":25,"studyType":54,"phases":55,"briefSummary":57,"conditions":58,"keywords":25,"overallStatus":61,"whyStopped":25,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":25},{"fullName":5,"class":6},"College of Physicians and Surgeons Pakistan","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Patency Group","EXPERIMENTAL",": A #10 K-file is passively advanced 1.0 mm beyond the major apical foramen before and after each successive instrumentation size to maintain patency.",[13,14],"Procedure: Patency Group","Procedure: Standard Root Canal Instrumentation",{"label":16,"type":17,"description":18,"interventionNames":19},"Non-Patency Group","ACTIVE_COMPARATOR","Participants in this group will receive standard root canal treatment where instruments are carefully confined to the root canal space and do not proceed beyond the apical foramen. All other aspects of the treatment are identical to the Experimental arm.",[13,14],[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","The procedural technique of passively advancing a small endodontic file (size #10 K-file) 1 mm beyond the apical foramen before and after each larger instrument during root canal cleaning and shaping. This is done to prevent blockage of the apical portion of the canal.",[16,9],null,{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard Root Canal Instrumentation","Root canal instrumentation that is strictly confined to the canal space, terminating at the apical constriction (working length) and avoiding any instrumentation beyond the apical foramen.",[16,9],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Faiz Rahman, BDS","CONTACT","+923451505838","faizr3702@gmail.com",{"type":37,"investigatorFullName":38,"investigatorTitle":39,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Faiz ur rahman","post graduate trainee","100611374","influence-of-maintaining-apical-patency-on-post-endodontic-pain-in-molars-100611374",false,"NCT07239752","Influence of Maintaining Apical Patency on Post-Endodontic Pain in Molars","Influence of Maintaining Apical Patency in Post-Endodontic Pain in Molars With Necrotic Pulp and Apical Periodontitis: A Randomized Controlled Trial","IMAP-Pain","Inclusion Criteria:Adult patients aged 18-65 years.\n\nMedically healthy, classified as American Society of Anesthesiologists (ASA) Physical Status I or II.\n\nPresence of a single permanent molar tooth diagnosed with necrotic pulp and symptomatic apical periodontitis, and indicated for primary root canal treatment.\n\nPatients who provide informed written consent to participate in the study. -\n\nExclusion Criteria:\n\nTeeth with prior endodontic treatment or complex anatomy (e.g., calcified canals, severe curvature).\n\nPatients with significant systemic illness (e.g., uncontrolled diabetes, immunocompromised status) or pregnancy.\n\nHistory of analgesic intake within 72 hours prior to the root canal procedure.\n\nNon-restorable teeth, teeth with severe periodontal disease (pocket depth \\>5mm), or teeth with root fractures.\n\nExclusion Criteria:\n\n\\-","ALL","18 Years","65 Years",{"count":52,"type":53},48,"ESTIMATED","INTERVENTIONAL",[56],"NA","This randomized controlled trial will investigate if maintaining apical patency-a technique where a small file is gently moved past the root's end during cleaning-affects pain after a root canal. The study will include 48 adult patients needing root canal treatment on a back molar tooth with a dead nerve and infection at the root tip. Participants will be randomly assigned to one of two groups: one where the apical patency technique is used, and one where it is not. All other treatment steps will be identical. Patients will record their pain levels on a standard scale (0-100 mm Visual Analog Scale) at 6, 12, 24, 48, and 72 hours after the procedure. The goal is to determine if this specific technique influences the intensity and duration of post-treatment pain",[59,60],"Periapical Periodontitis","Dental Pulp Necrosis","NOT_YET_RECRUITING","2025-11-16",{"date":64,"type":65},"2025-11-20","ACTUAL",{"date":67,"type":53},"2026-02-10",{"date":69,"type":53},"2026-10-10",{"name":5,"class":6}]