[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579822":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":13,"locations":22,"responsibleParty":43,"collaborators":7,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":7,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":54,"maxAge":7,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":7,"briefSummary":60,"conditions":61,"keywords":67,"overallStatus":25,"whyStopped":7,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Universitatsmedizin Mainz - 1. Medizinische Klinik","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Ultrasound","Sonographisch measurement of muscles Blood muscle markers",[14,19],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Wolfgang Maximilian Kremer Kremer, MD","CONTACT","00496131175711","maximilian.kremer@unimedizin-mainz.de",{"name":20,"role":16,"phone":21,"phoneExt":7,"email":7},"Christian Labenz Labenz, MD","0049 6131174209",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Universitatsmedizin Mainz","RECRUITING","Mainz","Rhineland-Palatinate","55131","Germany","DE",{"type":32,"coordinates":33},"Point",[34,35],8.28008,49.98185,{"lat":35,"lon":34},[38,41],{"name":39,"role":16,"phone":40,"phoneExt":7,"email":18},"Wolfgang Maximilian Kremer WMK Kremer, MD","00496131177134",{"name":39,"role":42,"phone":7,"phoneExt":7,"email":7},"PRINCIPAL_INVESTIGATOR",{"type":42,"investigatorFullName":44,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Wolfgang Maximilian Kremer","senior physician","100579822","influence-of-sarcopenia-on-the-course-of-the-diseases-100579822",false,"NCT06829290","Influence of Sarcopenia on the Course of the Diseases","Influence of Sarcopenia on the Course of the Diseases - Measured Using Ultrasound and Biochemical Markers","Inclusion Criteria:\n\n* oncological patient in the field of gastrointestinal tumors\n* patients with liver cirrhosis\n* patients attending the intensive care unit\n\nExclusion Criteria:\n\n* patients incapable of consenting\n* patients with congenital muscle diseases","ALL","18 Years",{"count":56,"type":57},200,"ESTIMATED","24 Months","OBSERVATIONAL","Frailty is a geriatric syndrome that primarily affects older patients, but also patients with severe illnesses. It is particularly common among oncology patients, but also among patients with gastrointestinal diseases such as liver cirrhosis or pancreatitis. Sarcopenia, a form of frailty, is defined as a loss of muscle quantity, quality and function. Currently, complex methods such as CT or bioimpedance measurement are available. However, simpler techniques such as ultrasound-based measurement could be alternatives, but still require further validation. In addition, serological muscle markers could support and simplify diagnostics.\n\nThe aim of this project is to be able to estimate the prognosis of patients at an early stage by measuring sarcopenia using ultrasound and biomarkers.",[62,63,64,65,66],"Liver Cirrhosis","Cancer","Cachexia","Sarcopenia","Mechanical Ventilation",[68,69],"sarcopenia","ultrasound","2025-02-10",{"date":72,"type":73},"2025-02-17","ACTUAL",{"date":75,"type":73},"2024-10-01",{"date":77,"type":57},"2028-10-01",{"name":5,"class":6},1]