[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567743":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":64,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":75,"eligibilityCriteria":76,"healthyVolunteers":71,"sex":77,"minAge":78,"maxAge":26,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":47,"whyStopped":26,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"St. Olavs Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Double sequential external defibrillation","EXPERIMENTAL","Patient will receive first shock using two defibrillators. All other aspects of resuscitation in accordance to existing guidelines.",[13],"Device: Two defibrillators",{"label":15,"type":16,"description":17,"interventionNames":18},"Standard treatment","ACTIVE_COMPARATOR","Standard treatment in accordance to existing Advanced Cardiopulmonary Resuscitation-guidelines using one defibrillator in anterior-lateral placement.",[19],"Device: One defibrillator",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Two defibrillators","DSED procedure consists of pads placed in anterior-lateral position, and in anterior-posterior position. Defibrillations will be given in rapid sequence, less than a second apart. All other aspects of resuscitation in accordance to existing guidelines.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"One defibrillator","Standard OHCA treatment according to existing guidelines.",[15],[32],{"name":33,"affiliation":5,"role":34},"Kjetil Karlsen","STUDY_DIRECTOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":26,"email":40},"Jostein R Brede, MD","CONTACT","+47 99445914","jostein.brede@norskluftambulanse.no",{"name":42,"role":38,"phone":26,"phoneExt":26,"email":43},"Vegard Nordviste, MD, PhD","vegard.nordviste@norskluftambulanse.no",[45],{"facility":46,"status":47,"city":48,"state":26,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"St Olavs Hospital","RECRUITING","Trondheim","7030","Norway","NO",{"type":53,"coordinates":54},"Point",[55,56],10.39506,63.43049,{"lat":56,"lon":55},[59,61],{"name":60,"role":38,"phone":26,"phoneExt":26,"email":40},"Jostein R Brede, MD, PhD",{"name":62,"role":63,"phone":26,"phoneExt":26,"email":26},"Vegard Nordviste, MD","SUB_INVESTIGATOR",{"type":65,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[67],{"name":68,"class":6},"Norwegian Air Ambulance Foundation","100567743","initial-double-sequential-external-defibrillation-in-out-of-hospital-cardiac-arrest-100567743",false,"NCT06672159","Initial Double Sequential External Defibrillation in Out of Hospital Cardiac Arrest","A Randomized Controlled Trial on Early Double External Sequential Defibrillation in Out of Hospital Cardiac Arrest","DUALDEFIB","Inclusion Criteria:\n\n* Patients with out of hospital cardiac arrest presenting with a shockable rhythm\n\nExclusion Criteria:\n\n* Age below 18 years\n* Obvious or suspected pregnancy\n* Incarcerated patients\n* Preexisting do-not-resuscitate order","ALL","18 Years",{"count":80,"type":81},356,"ESTIMATED","INTERVENTIONAL",[84],"NA","Double Sequential External Defibrillation (DSED) represents an alternative treatment of refractory ventricular fibrillation (rVF) in out-of-hospital cardiac arrest (OHCA). The procedure consists of two defibrillators that administer shocks at the same time.\n\nCurrently, the procedure is not initiated before at least three failed attempts with one defibrillator. This can delay the potential benefits of establishing DSED earlier in the treatment. Studies have shown that early defibrillation is crucial for survival in OHCA patients, and in 2022, a clinical trial showed that survival in patients treated with DSED was higher compared to standard treatment.\n\nThe effect of initiating OHCA treatment is unknown. The DUALDEFIB trial seeks to investigate if treating OHCA patients with DSED as an initial treatment will increase survival and provide improved neurological outcome.",[87,88,89],"Cardiac Arrest","Out-Of-Hospital Cardiac Arrest","Ventricular Fibrillation",[91,92],"Double defibrillation","Cardiopulmonary resuscitation","2025-06-04",{"date":95,"type":96},"2025-06-05","ACTUAL",{"date":98,"type":96},"2025-04-28",{"date":100,"type":81},"2028-10",{"name":5,"class":6},1]