[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633042":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":32,"responsibleParty":46,"collaborators":20,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":20,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":20,"enrollmentInfo":58,"targetDuration":20,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":73,"whyStopped":20,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Capital Medical University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Integrated Multidisciplinary Rehabilitation in HDU","EXPERIMENTAL","Participants transferred from the intensive care unit (ICU) to the high-dependency unit (HDU) who meet the diagnostic criteria for post-intensive care syndrome (PICS) will receive an integrated multidisciplinary rehabilitation program during their HDU stay.\n\nThe intervention includes coordinated medical management, respiratory rehabilitation, physical rehabilitation, rehabilitation nursing, and cognitive and psychological interventions delivered by a multidisciplinary team.",[13],"Behavioral: Integrated Multidisciplinary Rehabilitation",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"BEHAVIORAL","Integrated Multidisciplinary Rehabilitation","Participants will receive a standardized multidisciplinary rehabilitation program implemented in the HDU, including:\n\nMedical management Continuous treatment of primary diseases, medication optimization, complication prevention, and gradual removal of medical devices.\n\nRespiratory rehabilitation Respiratory muscle training, airway clearance techniques, and breathing pattern training.\n\nPhysical rehabilitation Progressive mobilization according to patient tolerance, including passive exercises, active bed exercises, sitting training, standing training, and walking training.\n\nSessions are conducted 1-2 times per day, lasting 20-40 minutes each.\n\nRehabilitation nursing Position management, pressure injury prevention, device safety management, and sleep management.\n\nCognitive and psychological interventions Orientation training, cognitive stimulation activities, psychological support, and family participation.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Hongying Jiang, MD","Beijing Rehabilitation Hospital of Capital Medical University","STUDY_CHAIR",[27],{"name":28,"role":29,"phone":30,"phoneExt":20,"email":31},"Jingyi Ge","CONTACT","+861056981098","ge_jingyi2020@163.com",[33],{"facility":34,"status":20,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":20},"Beijing Rehabilitation Hospital Affiliated to Capital Medical University","Beijing","Shijingshan","100144","China","CN",{"type":41,"coordinates":42},"Point",[43,44],116.39723,39.9075,{"lat":44,"lon":43},{"type":47,"investigatorFullName":23,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"SPONSOR_INVESTIGATOR","Sponsor-Investigator","100633042","integrated-rehabilitation-in-hdu-for-post-intensive-care-syndromeliberation-in-patients-with-pics-100633042",false,"NCT07521540","Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS","Effect of Integrated Multidisciplinary Rehabilitation in a High-Dependency Unit on Outcomes of Patients With Post-Intensive Care Syndrome: A Prospective Interventional Study","Inclusion Criteria:\n\n* Age ≥18 years\n* Diagnosed with post-intensive care syndrome\n* Transferred from ICU to HDU\n* Available paired admission and discharge data\n\nExclusion Criteria:\n\n* Death within 24 hours after HDU admission\n* Missing primary outcome data","ALL","18 Years",{"count":59,"type":60},250,"ESTIMATED","INTERVENTIONAL",[63],"NA","Post-intensive care syndrome (PICS) is characterized by persistent physical, cognitive, and psychological impairments among survivors of critical illness. Although advances in intensive care medicine have reduced mortality, a large proportion of ICU survivors experience long-term functional impairments after discharge.\n\nHigh-dependency units (HDUs) serve as transitional care settings between intensive care units and general wards. Many critically ill survivors who cannot directly return home are transferred to HDU for continued treatment and rehabilitation. However, evidence regarding systematic multidisciplinary rehabilitation interventions in HDU settings remains limited.\n\nThis prospective single-center interventional study aims to evaluate the effects of an integrated multidisciplinary rehabilitation model implemented in the HDU on physical, cognitive, and psychological outcomes among patients with post-intensive care syndrome. All enrolled patients will receive standardized integrated medical, nursing, and rehabilitation interventions. Multidimensional functional assessments will be conducted at baseline, during hospitalization, and before discharge from the HDU.",[66,67,68],"Post-Intensive Care Syndrome (PICS)","Critical Illness Recovery","Mechanical Ventilation",[70,71,72],"Ventilator liberation","High-dependency unit","Post-ICU rehabilitation","NOT_YET_RECRUITING","2026-04-08",{"date":76,"type":77},"2026-04-13","ACTUAL",{"date":79,"type":60},"2026-04-01",{"date":81,"type":60},"2027-12-31",{"name":23,"class":6},1]