[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622071":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":26,"locations":36,"responsibleParty":67,"collaborators":71,"id":73,"slug":74,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":77,"acronym":10,"eligibilityCriteria":78,"healthyVolunteers":79,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":10,"studyType":86,"phases":10,"briefSummary":87,"conditions":88,"keywords":90,"overallStatus":94,"whyStopped":10,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"Universiti Sains Malaysia","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"Mycoplasma pneumoniae pneumonia (MPP) group",null,"Children with Mycoplasma pneumoniae pneumonia",{"label":13,"type":10,"description":14,"interventionNames":10},"Non-mycoplasma acute respiratory tract infection (NMP) group","Children with acute respiratory tract infection without Mycoplasma pneumoniae",{"label":16,"type":10,"description":17,"interventionNames":10},"Recurrent respiratory tract infections (RRTIs) group","Children with recurrent respiratory tract infections",{"label":19,"type":10,"description":20,"interventionNames":10},"Healthy control group","Healthy children without any respiratory disease",[22],{"name":23,"affiliation":24,"role":25},"Yongli Dai, MD.","940 Hospital of the People's Liberation Army Joint Logistic Support Force","PRINCIPAL_INVESTIGATOR",[27,32],{"name":28,"role":29,"phone":30,"phoneExt":10,"email":31},"Yuan Jie, M.Sc.","CONTACT","822137027899","peanut.yuan@diprobio.com",{"name":33,"role":29,"phone":34,"phoneExt":10,"email":35},"Min Tze Liong, Ph.D.","6046532114","mintze.liong@usm.my",[37,58],{"facility":38,"status":10,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"The 940th Hospital of the Joint Logistic Support Force of the Chinese People's Liberation Army","Lanzhou","Gansu","730000","China","CN",{"type":45,"coordinates":46},"Point",[47,48],103.83987,36.05701,{"lat":48,"lon":47},[51,54,56,57],{"name":23,"role":29,"phone":52,"phoneExt":10,"email":53},"(0931) 2938150","xbmdyxb163@163.com",{"name":55,"role":29,"phone":52,"phoneExt":10,"email":53},"Yan Xu, MD.",{"name":23,"role":25,"phone":10,"phoneExt":10,"email":10},{"name":55,"role":25,"phone":10,"phoneExt":10,"email":10},{"facility":5,"status":10,"city":59,"state":59,"zip":60,"country":61,"countryCode":62,"cosmosGeoPoint":10,"geoPoint":10,"contacts":63},"Pulau Pinang","11800","Malaysia","MY",[64,65],{"name":33,"role":29,"phone":34,"phoneExt":10,"email":35},{"name":28,"role":29,"phone":66,"phoneExt":10,"email":31},"86 198 2187 2781",{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Min-Tze LIONG","Prof.",[72],{"name":24,"class":6},"100622071","integrated-study-on-gut-microbiota-immune-indicators-and-trace-elements-in-children-with-respiratory-tract-infections-100622071",false,"NCT07378852","Integrated Study on Gut Microbiota, Immune Indicators, and Trace Elements in Children With Respiratory Tract Infections","Inclusion Criteria\n\n1. Aged 3-14 years;\n2. Good compliance and complete clinical data;\n3. Guardians are informed and sign written consent;\n4. MPP group: meets diagnostic criteria of Guidelines for Diagnosis and Treatment of Mycoplasma Pneumoniae Pneumonia in Children (2023 Edition);\n5. NMP group: acute respiratory tract infection with negative MP-DNA\u002FRNA;\n6. RRTIs group: meets diagnostic criteria of Clinical Diagnosis and Treatment Pathway for Recurrent Respiratory Tract Infections in Children (2022 Edition);\n7. Healthy controls: no respiratory infection history within the past month.\n\nExclusion Criteria\n\n1. Other infectious diseases (e.g., measles, pertussis, tuberculosis);\n2. Congenital heart disease, immunodeficiency, or major organ dysfunction;\n3. Use of antibiotics, probiotics, immunomodulators, hormones, or microecological preparations within the past 15-30 days;\n4. Unqualified biological samples or incomplete laboratory data.",true,"ALL","3 Years","14 Years",{"count":84,"type":85},120,"ESTIMATED","OBSERVATIONAL","This observational study aims to investigate the characteristics of gut microbiota and their associations with immune and nutritional indicators in children with different respiratory health statuses. A total of 120 children will be enrolled and categorized into four groups: children with Mycoplasma pneumoniae pneumonia (MPP), children with acute respiratory tract infections without Mycoplasma pneumoniae (NMP), children with recurrent respiratory tract infections (RRTIs), and healthy controls. By comparing gut microbiota composition and diversity, as well as immune- and nutrition-related indicators across groups, this study seeks to clarify the potential role of intestinal dysbiosis and host immune-nutritional interactions in the pathogenesis and clinical manifestations of pediatric respiratory tract infections.",[89],"Respiratory",[91,92,93],"children","respiratory","gut microbiota","NOT_YET_RECRUITING","2026-02-01",{"date":97,"type":98},"2026-02-04","ACTUAL",{"date":100,"type":85},"2026-01-30",{"date":102,"type":85},"2026-06-30",{"name":69,"class":6},2]