[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602119":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":56,"collaborators":59,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":74,"minAge":75,"maxAge":19,"enrollmentInfo":76,"targetDuration":19,"studyType":79,"phases":80,"briefSummary":82,"conditions":83,"keywords":86,"overallStatus":41,"whyStopped":19,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"University of Washington","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Home-based HIV self-testing and PrEP initiation","EXPERIMENTAL","Home-based HIV self-testing and PrEP initiation (for eligible participants) integrated into routine TB household contact investigation",[13,14],"Other: Home-based HIV self-testing","Other: Home-based initiation of PrEP",{"label":16,"type":17,"description":18,"interventionNames":19},"Modified standard of care","NO_INTERVENTION","Referral to health facility for HIV testing and PrEP initiation",null,[21,25],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":19},"Home-based HIV self-testing","Integration of HIV self-testing into TB household contact investigation",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":19},"Home-based initiation of PrEP","Integration of PrEP initiation into TB household contact investigation",[9],[30],{"name":31,"affiliation":5,"role":32},"Jennifer M Ross, MD, MPH","PRINCIPAL_INVESTIGATOR",[34],{"name":31,"role":35,"phone":36,"phoneExt":19,"email":37},"CONTACT","206 543-9192","jross3@uw.edu",[39],{"facility":40,"status":41,"city":42,"state":19,"zip":19,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Infectious Diseases Institute","RECRUITING","Kampala","Uganda","UG",{"type":46,"coordinates":47},"Point",[48,49],32.58219,0.31628,{"lat":49,"lon":48},[52],{"name":53,"role":35,"phone":54,"phoneExt":19,"email":55},"Andrew Mujugira","+256 392 265 887","amujugira@idi.co.ug",{"type":32,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Jennifer Ross","Assistant Professor, Department of Medicine, Division of Allergy and Infectious Diseases",[60,62],{"name":61,"class":6},"Infectious Diseases Institute, Uganda",{"name":63,"class":64},"National Institute of Mental Health (NIMH)","NIH","100602119","integrating-hiv-prevention-with-tb-household-contact-evaluation-in-uganda-100602119",false,"NCT07119359","Integrating HIV Prevention With TB Household Contact Evaluation in Uganda","Integrating HIV Prevention With TB Household Contact Evaluation in Uganda (TB PrEP)","TB PrEP","Inclusion Criteria:\n\n* Person with pulmonary TB OR live in a household with someone with pulmonary TB being treated at one of the participating health facilities\n* Household includes ≥2 persons\n* Age 15 years and older\n* Willingness to participate in study procedures\n\nExclusion Criteria:\n\n* Lives in a congregate setting (e.g., dormitory or jail)\n* Lives outside the study area\n* Any other condition that, in the opinion of the Investigator\u002Fdesignee, could preclude informed consent, make study participation unsafe, or otherwise interfere with achieving study objectives",true,"ALL","15 Years",{"count":77,"type":78},2480,"ESTIMATED","INTERVENTIONAL",[81],"NA","This household randomized implementation study assesses the implementation and effectiveness of home-based HIV self- testing and PrEP initiation versus standard clinic referral for PrEP initiation during modified standard-of-care (modified SOC) household TB contact investigation in Uganda. It uses qualitative methods to evaluate the process of implementing the intervention and a health economic evaluation to assess the financial sustainability of this strategy.",[84,85],"Tuberculosis (TB)","Human Immunodeficiency Virus (HIV) Prophylaxis",[43,87,88,89,90,91],"TB contact tracing","HIV","Tuberculosis","PrEP","Household","2026-04-29",{"date":94,"type":95},"2026-05-05","ACTUAL",{"date":97,"type":95},"2025-12-10",{"date":99,"type":78},"2029-08-31",{"name":5,"class":6},1]