[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538082":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":38,"responsibleParty":97,"collaborators":99,"id":103,"slug":104,"hasResults":105,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":24,"eligibilityCriteria":109,"healthyVolunteers":105,"sex":110,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":24,"studyType":116,"phases":117,"briefSummary":119,"conditions":120,"keywords":123,"overallStatus":41,"whyStopped":24,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},{"fullName":5,"class":6},"Singapore Institute of Technology","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cognitive Remediation: Adapted Neuropsychological and Education Approach to Remediation (NEAR)","EXPERIMENTAL","NEAR consists of using carefully selected computer cognitive games to restore cognitive functioning through rehearsal and strategy learning. It will be delivered 3 times a week for 12 weeks at the center. The duration of each session within the week is as follows: 1) First session: 45 min computer-assisted cognitive exercises + 30 min bridging group; 2) Second session: 30 min computer-assisted cognitive exercises + 45 min bridging group; 3) Third session: 45 min computer-assisted cognitive exercises. Computer-assisted cognitive exercises are sessions where participants engage in cognitive games that target different cognitive domains. In addition, the Multicontext Treatment Approach to strategy learning will be carried out. The metacognitive framework of self-evaluation and activity mediation will also be utilized. Bridging groups are conducted twice a week, to aid transfer of learning from the computer game sessions to the participants' everyday life.",[13],"Behavioral: Cognitive Remediation: Adapted Neuropsychological and Education Approach to Remediation (NEAR)",{"label":15,"type":6,"description":16,"interventionNames":17},"Standard Psychiatric Rehabilitation at Anglican Care Centers","Participants in the control arm will attend their scheduled activities at their respective Anglican Care Centers. The Anglican Care Centers run a variety of activities to provide psychosocial rehabilitation for clients with serious mental illness. These may include vocational training such as training in a retail shop or café, instrumental activities of daily living training (eg: taking public transport, money management), psychoeducation, social skills training etc. Participants in the control arm will not be enrolled into the cognitive remediation.",[18],"Behavioral: Standard Psychiatric Rehabilitation at Anglican Care Centers",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","NEAR consists of computer-assisted cognitive exercises to restore cognitive functioning through rehearsal and strategy learning. Based on the results of the baseline assessments, the therapist will complete the Cognitive Remediation Treatment Plan, to outline targeted cognitive domains and functional goals. During the cognitive games sessions, the Multicontext Treatment Approach will be used, where error patterns are identified. The participants will work on metacognition and use of strategies to overcome challenges faced during the computer games sessions. Bridging groups may include activities for participants to utilize strategies learnt during the computer game sessions to everyday living. Participants will also learn about cognitive impairments and how lifestyle modifications, mood regulation etc can affect cognitive performance. In addition, they will learn about metamotivation and build awareness about their motivation levels through self- reflection and self-monitoring.",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Participants in the control arm will attend their usual psychiatric rehabilitation activities. These activities may include vocational training, community living skills training, psychoeducation, social skills training and peer support etc. These activities are also undertaken by participants in the experimental arm.",[15],[29],{"name":30,"affiliation":31,"role":32},"Bhing-Leet Tan, PhD","Bhing-Leet Tan","PRINCIPAL_INVESTIGATOR",[34],{"name":30,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","+6598422783","bhingleet.tan@singaporetech.edu.sg",[39,55,66,77,87],{"facility":40,"status":41,"city":42,"state":24,"zip":24,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Anglican Care Center-Bukit Batok","RECRUITING","Singapore","SG",{"type":45,"coordinates":46},"Point",[47,48],103.85007,1.28967,{"lat":48,"lon":47},[51],{"name":52,"role":35,"phone":53,"phoneExt":24,"email":54},"Jonathan Poh, MA","+6592333020","Jonathan_poh@sacs.org.sg",{"facility":56,"status":41,"city":42,"state":24,"zip":24,"country":42,"countryCode":43,"cosmosGeoPoint":57,"geoPoint":59,"contacts":60},"Anglican Care Center-Hougang",{"type":45,"coordinates":58},[47,48],{"lat":48,"lon":47},[61],{"name":62,"role":35,"phone":63,"phoneExt":64,"email":65},"Vanessa Koh, BSc (Hons)","+6563869338","101","vanessa_koh@sacs.org.sg",{"facility":67,"status":68,"city":42,"state":24,"zip":24,"country":42,"countryCode":43,"cosmosGeoPoint":69,"geoPoint":71,"contacts":72},"Anglican Care Center-Pasir Ris","NOT_YET_RECRUITING",{"type":45,"coordinates":70},[47,48],{"lat":48,"lon":47},[73],{"name":74,"role":35,"phone":75,"phoneExt":24,"email":76},"Joseph Tee, Master of Psychology","+656584 4633","joseph_tee@sacs.org.sg",{"facility":78,"status":41,"city":42,"state":24,"zip":24,"country":42,"countryCode":43,"cosmosGeoPoint":79,"geoPoint":81,"contacts":82},"Anglican Care Center-Simei",{"type":45,"coordinates":80},[47,48],{"lat":48,"lon":47},[83],{"name":84,"role":35,"phone":85,"phoneExt":24,"email":86},"Noel Tan, MA","+6591853094","noel_tan@sacs.org.sg",{"facility":88,"status":68,"city":42,"state":24,"zip":24,"country":42,"countryCode":43,"cosmosGeoPoint":89,"geoPoint":91,"contacts":92},"Anglican Care Center-Yishun",{"type":45,"coordinates":90},[47,48],{"lat":48,"lon":47},[93],{"name":94,"role":35,"phone":95,"phoneExt":24,"email":96},"Cindy Low, Master of Counselling","_656753 5311","cindy_low@sacs.org.sg",{"type":32,"investigatorFullName":31,"investigatorTitle":98,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Professor and Cluster Director",[100],{"name":101,"class":102},"Singapore Anglican Community Services","UNKNOWN","100538082","integrative-neuro-social-cognitive-strategy-programme-for-instilling-recovery-inspire-a-community-based-cognitive-remediation-trial-100538082",false,"NCT06286202","Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE) a Community-Based Cognitive Remediation Trial","Integrative Neuro-social Cognitive Strategy Programme for Instilling REcovery (INSPIRE): a Community-Based Cognitive Remediation Trial","Inclusion Criteria:\n\n* A diagnosis of schizophrenia or schizoaffective disorder according to Diagnostic and Statistical Manual of Mental Disorders-5th Edition (DSM-V).\n* Completed at least ten years of formal education with English as the main instructional language. Participants need to be able to converse in English and understand English instructions, as the cognitive remediation program will be conducted in English.\n\nExclusion Criteria:\n\n* Known neurological diseases and epilepsy, which affects gains from cognitive remediation.\n* Unable to speak and understand English.\n* Hospitalized within the past one month.\n* Global Assessment of Functioning score of 30 or below, as participants who are too low functioning are unable to benefit from a strategy learning approach.","ALL","21 Years","60 Years",{"count":114,"type":115},160,"ESTIMATED","INTERVENTIONAL",[118],"NA","Adults with serious mental illnesses (such as schizophrenia and schizoaffective disorders) often experience a range of cognitive difficulties (such as memory, problem solving difficulties) that affect their ability to lead meaningful life roles. Cognitive remediation is an intervention to address cognitive difficulties in this group of mental health service users. Its implementation in less well-resourced community-based settings is less well-studied.\n\nTherefore, the aims of the study are:\n\n* To investigate the effects of cognitive remediation on various cognitive skills (such as attention, memory, problem-solving, facial expression recognition, taking others' perspectives etc), for participants with schizophrenia or schizoaffective disorders in community mental health settings.\n* To investigate if factors such as participants' motivation for engagement and social interaction can affect changes in cognitive skills and functional ability.\n\nParticipants in the treatment group will attend computer-based cognitive exercises to improve their cognitive skills. They will also participate in group sessions facilitated by therapists to learn how to utilize strategies learned from the computer sessions in their daily lives. Participants in the control group will attend the usual rehabilitation activities in their respective community-based psychiatric rehabilitation centers.\n\nThis research study will compare the differences in their cognitive performance, functional ability and recovery immediately after the intervention and 8 weeks later.",[121,122],"Schizophrenia","Schizoaffective Disorder",[124,125,126,127,128,129,130],"cognitive remediation","Neuropsychological and Educational Approach to Remediation","Multicontext Treatment Approach","metamotivation","psychiatric rehabilitation","schizophrenia","community mental health","2026-01-25",{"date":133,"type":134},"2026-01-27","ACTUAL",{"date":136,"type":134},"2024-08-06",{"date":138,"type":115},"2027-12",{"name":5,"class":6},5]