[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100561856":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":24,"locations":33,"responsibleParty":105,"collaborators":107,"id":116,"slug":117,"hasResults":118,"nctId":119,"briefTitle":120,"officialTitle":121,"acronym":122,"eligibilityCriteria":123,"healthyVolunteers":118,"sex":124,"minAge":125,"maxAge":10,"enrollmentInfo":126,"targetDuration":10,"studyType":129,"phases":10,"briefSummary":130,"conditions":131,"keywords":134,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":149},{"fullName":5,"class":6},"Technische Universität Dresden","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Invasively mechanically ventilated patients expected to stay ventilated for more than 24 h.",null,[12],"Device: Artificial intelligence based decision support system (AI-DSS); software",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":10},"DEVICE","Artificial intelligence based decision support system (AI-DSS); software","The device is intended for monitoring and recommending ventilator settings, ventilation mode to qualified Intensive Care Unit (ICU) health care professionals (HCP). This is for medical indications that require invasive mechanical ventilation of the respiratory system in the ICU under international \u002F EU guidelines.\n\nThe device receives clinical data via the ICU's data integration platform that includes patient physical and demographic data as well as current vital signs, ventilation parameters, blood gas analysis, general blood laboratory reports, fluid balance and medication. Prediction models based on artificial intelligence algorithms are used to deduce therapy suggestions from received data. The algorithm is carried out on a secured cloud platform.",[9],[20],{"name":21,"affiliation":22,"role":23},"Jakob Wittenstein","epartment of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Jakob Wittenstein, M.D.","CONTACT","+49 351 458 19777","jakob.wittenstein@ukdd.de",{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},"Raphael Theilen","raphael.theilen@ukdd.de",[34,50,65,79,93],{"facility":35,"status":36,"city":37,"state":10,"zip":38,"country":39,"countryCode":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany","RECRUITING","Dresden","01307","Germany","DE",{"type":42,"coordinates":43},"Point",[44,45],13.73832,51.05089,{"lat":45,"lon":44},[48],{"name":49,"role":27,"phone":28,"phoneExt":10,"email":29},"Jakob Wittenstein, MD",{"facility":51,"status":52,"city":53,"state":10,"zip":10,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":60,"contacts":61},"Dipartimento di Scienze Chirurgiche e Diagnostiche Integrate, University of Genoa, Genoa, Italy","NOT_YET_RECRUITING","Genova","Italy","IT",{"type":42,"coordinates":57},[58,59],11.87211,45.21604,{"lat":59,"lon":58},[62],{"name":63,"role":27,"phone":10,"phoneExt":10,"email":64},"Lorenzo Ball","lorenzo.ball@unige.it",{"facility":66,"status":36,"city":67,"state":10,"zip":10,"country":68,"countryCode":69,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"Department of Anaesthesiology and Intensive Care, National Medical Institute of the Ministry of Interior and Administration, Warsaw, Poland","Warsaw","Poland","PL",{"type":42,"coordinates":71},[72,73],21.01178,52.22977,{"lat":73,"lon":72},[76],{"name":77,"role":27,"phone":10,"phoneExt":10,"email":78},"Konstanty Szuldrzynski","konstanty.szuldrzynski@pimmswia.gov.pl",{"facility":80,"status":52,"city":81,"state":10,"zip":10,"country":82,"countryCode":83,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"Department of Intensive Care Medicine. Hospital Universitario de La Princesa. Universidad Autonoma de Madrid, Madrid, Spain","Madrid","Spain","ES",{"type":42,"coordinates":85},[86,87],-3.70256,40.4165,{"lat":87,"lon":86},[90],{"name":91,"role":27,"phone":10,"phoneExt":10,"email":92},"Fernando Suarez Sipmann","fsuarezsipmann@gmail.com",{"facility":94,"status":36,"city":95,"state":10,"zip":10,"country":82,"countryCode":83,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Critical Care Department, Parc Taulí Hospital Universitari, Institut d'Investigació I Innovació Parc Taulí (I3PT-CERCA), Sabadell, Spain","Sabadell",{"type":42,"coordinates":97},[98,99],2.10942,41.54329,{"lat":99,"lon":98},[102],{"name":103,"role":27,"phone":10,"phoneExt":10,"email":104},"Lluis Blanch","lblanch@tauli.cat",{"type":106,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[108,110,111,113,114],{"name":51,"class":109},"UNKNOWN",{"name":94,"class":109},{"name":112,"class":109},"Department of Anaesthesiology and Intensive Care, National Medical Institute of the Ministry of Interior and Administration, Warsaw, Polan",{"name":80,"class":109},{"name":115,"class":109},"Department of Anesthesiology and Intensive Care Medicine, Pulmonary Engineering Group, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresde","100561856","intelligent-lung-support-in-the-intensive-care-unit-100561856",false,"NCT06595602","Intelligent Lung Support in the Intensive Care Unit","Intelligent Lung Support in the Intensive Care Unit (IntelliLung): An Observational, Prospective, Multicentre Study","IntelliLung","Inclusion Criteria:\n\n1. Male and female patients, age ⪰18 years\n2. Written informed consent\n3. Invasively mechanically ventilated patients expected to be intubated for more than 24 hours.\n\nExclusion Criteria:\n\n1. Expected to die within ≤48 hours\n2. Participation in an interventional mechanical ventilation trial\n3. Mechanical Ventilation with a closed-loop ventilation mode\n4. Persons dependent on the sponsor and\u002For investigator\n5. Subjects who are currently imprisoned or otherwise in confinement ordered by law or other official authorities","ALL","18 Years",{"count":127,"type":128},530,"ESTIMATED","OBSERVATIONAL","The aim of this observational study is to test the IntelliLung decision support system based on artificial intelligence. This system is intended to help to set the ventilator. The study includes patients with and without ARDS (acute respiratory distress syndrome) who are receiving invasive mechanical ventilation, as well as patients with additional extracorporeal lung support. The study will be conducted in several centers.\n\nThe main question of the study:\n\nHow well do the mechanical ventilation settings of healthcare staff match the recommendations of the IntelliLung system?",[132,133],"Mechanical Ventilation","Intensive Care Medicine",[135,136,137,138,139],"Invasive mechanical ventilation","Intensive care medicine","critical care medicine","artificial intelligence","decision support","2026-06-30",{"date":142,"type":143},"2026-07-02","ACTUAL",{"date":145,"type":143},"2025-05-25",{"date":147,"type":128},"2027-12",{"name":5,"class":6},5]