[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100643650":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":13,"locations":7,"responsibleParty":19,"collaborators":7,"id":23,"slug":24,"hasResults":25,"nctId":26,"briefTitle":27,"officialTitle":28,"acronym":29,"eligibilityCriteria":30,"healthyVolunteers":25,"sex":31,"minAge":32,"maxAge":7,"enrollmentInfo":33,"targetDuration":7,"studyType":36,"phases":7,"briefSummary":37,"conditions":38,"keywords":42,"overallStatus":45,"whyStopped":7,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":7},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Carbohydrate-Deficient Transferrin (CDT) Measurement","Carbohydrate-deficient transferrin (CDT) measurement is performed at ICU admission as an objective biomarker of sustained hazardous alcohol consumption during the previous 1-3 weeks. CDT values are obtained from routinely collected blood samples in adult non-traumatic ICU patients admitted via the emergency department. The study is purely observational and does not involve administration of a therapeutic intervention or changes to standard clinical care. CDT levels are analyzed in relation to outcomes including 30-day mortality, ICU length of stay, mechanical ventilation, delirium, renal replacement therapy, and ICU readmission.",[14],{"name":15,"role":16,"phone":17,"phoneExt":7,"email":18},"Juergen Grafeneder, MD, PhD MSc","CONTACT","‭+43 1 4040019640‬","juergen.grafeneder@meduniwien.ac.at",{"type":20,"investigatorFullName":21,"investigatorTitle":22,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Juergen Grafeneder","Principal Investigator","100643650","intensive-care-outcome-prediction-using-admission-carbohydrate-deficient-transferrin-100643650",false,"NCT07632716","Intensive Care Outcome Prediction Using Admission Carbohydrate-deficient Transferrin","IMPACT - Intensive Care Outcome Prediction Using Admission Carbohydrate-deficient Transferrin A Prospective Single-center Cohort Study","IMPACT","Inclusion Criteria:\n\n* all patients ≥ 18 admitted to the Department of Emergency Medicine and subsequently transferred to an in-house intensive care unit (ICU)\n\nExclusion Criteria:\n\n* Patients transferred to other hospital departments prior to completion of intensive care\n* Patients admitted directly to the ICU without passing the ED\n* Patients admitted to intermediate care units\n* Patients with pre-existing or newly diagnosed hepatic cirrhosis\n* Patients with known or obvious pregnancy will be excluded.\n* Patients with no vascular access","ALL","18 Years",{"count":34,"type":35},800,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn whether hazardous alcohol consumption, measured objectively by carbohydrate-deficient transferrin (CDT) levels at intensive care unit (ICU) admission, is associated with worse outcomes in critically ill patients. The main question it aims to answer is:\n\nDo elevated CDT levels at ICU admission predict increased short-term mortality and adverse clinical outcomes in adult non-traumatic ICU patients? Participants admitted to the intensive care unit via the emergency department will have CDT levels measured as part of the study. Researchers will then collect and analyze clinical data, including mortality, duration of mechanical ventilation, delirium, ICU length of stay, renal replacement therapy, and ICU readmission rates, during hospitalization and follow-up.",[39,40,41],"Intensive Care (ICU)","Critical Illness","Alcohol Misuse",[43,40,44],"Alcohol-Related Disorders","Intensive Care Units","NOT_YET_RECRUITING","2026-06-02",{"date":48,"type":49},"2026-06-08","ACTUAL",{"date":51,"type":35},"2026-06",{"date":53,"type":35},"2028-07",{"name":5,"class":6}]