[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639386":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":22,"locations":32,"responsibleParty":45,"collaborators":21,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":21,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":57,"minAge":58,"maxAge":21,"enrollmentInfo":59,"targetDuration":21,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":75,"whyStopped":21,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Tel Aviv University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Healthy Adult Participants","EXPERIMENTAL","Healthy adults (≥18 years) participating in a single laboratory visit. All participants undergo resting metabolic rate assessment, consume a standardized liquid meal (550 kcal), and complete continuous postprandial energy expenditure measurement using indirect calorimetry under controlled conditions.",[13],"Other: Standardized Liquid Meal",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Standardized Liquid Meal","Consumption of a standardized liquid meal (\\~550 kcal) under controlled laboratory conditions, followed by continuous measurement of energy expenditure using indirect calorimetry for assessment of postprandial thermogenesis. The procedure is used for measurement purposes only and is not intended as a therapeutic intervention.",[9],[20],"Ensure®",null,[23,28],{"name":24,"role":25,"phone":26,"phoneExt":21,"email":27},"Yftach Prof. Gepner","CONTACT","0506828501","gepner@tauex.tau.ac.il",{"name":29,"role":25,"phone":30,"phoneExt":21,"email":31},"Lien Bruck","0587487431","lienbruck@tauex.tau.ac.il",[33],{"facility":34,"status":21,"city":35,"state":21,"zip":36,"country":37,"countryCode":38,"cosmosGeoPoint":39,"geoPoint":44,"contacts":21},"Sylvan Adams Sport Science Institute","Tel Aviv","6428607","Israel","IL",{"type":40,"coordinates":41},"Point",[42,43],34.78057,32.08088,{"lat":43,"lon":42},{"type":46,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":21,"oldOrganization":21},"PRINCIPAL_INVESTIGATOR","Gepner Yftach","Principal Investigator - Professor","100639386","inter-individual-variability-in-early-diet-induced-thermogenesis-after-a-standardized-meal-100639386",false,"NCT07610759","Inter-Individual Variability in Early Diet-Induced Thermogenesis After a Standardized Meal","Inter-Individual Variability in Early Postprandial Thermogenesis Following a Standardized Liquid Meal","Inclusion Criteria:\n\n* Adults aged ≥18 years\n* Stable body weight (±2 kg over the previous 3 months)\n* Generally healthy individuals\n* Ability to comply with study procedures, including fasting and remaining at rest - during measurements\n\nExclusion Criteria:\n\n* Use of medications known to affect metabolism (e.g., GLP-1 receptor agonists, systemic corticosteroids, uncontrolled thyroid disease)\n* Insulin-treated diabetes\n* Pregnancy or lactation\n* Acute illness at the time of testing\n* Inability to comply with pre-test requirements (e.g., fasting, avoiding caffeine, alcohol, or physical activity)",true,"ALL","18 Years",{"count":60,"type":61},30,"ESTIMATED","INTERVENTIONAL",[64],"NA","This study aims to characterize how individuals differ in their metabolic response to food intake, specifically focusing on early diet-induced thermogenesis (DIT). DIT refers to the increase in energy expenditure that occurs after eating and reflects the body's metabolic response to processing nutrients.\n\nHealthy adult participants will complete a single laboratory visit under standardized conditions. Resting metabolic rate will first be measured, followed by consumption of a standardized liquid meal (550 kcal). Energy expenditure will then be continuously monitored for 3 hours using indirect calorimetry.\n\nThe primary objective is to quantify inter-individual variability in early postprandial thermogenesis. Rather than estimating total daily energy expenditure, this study focuses on the early metabolic response following meal ingestion. Findings will improve understanding of differences in metabolic efficiency between individuals and support future research in metabolism and personalized nutrition.",[67],"Diet-induced Thermogenesis",[69,70,71,72,73,74],"Diet-induced thermogenesis","Postprandial metabolism","Energy expenditure","Metabolic variability","Indirect calorimetry","Standardized meal","NOT_YET_RECRUITING","2026-05-27",{"date":78,"type":79},"2026-05-28","ACTUAL",{"date":81,"type":61},"2026-06",{"date":83,"type":61},"2027-06",{"name":5,"class":6},1]