[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641783":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":54,"collaborators":25,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":58,"sex":64,"minAge":65,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":87,"whyStopped":25,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":97},{"fullName":5,"class":6},"Hopital Foch","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Endometriosis Group","EXPERIMENTAL","Adult women with confirmed deep endometriosis undergoing collection of clinical data and biological samples, including blood, endometrial tissue, vaginal microbiota samples, and, when clinically indicated, additional samples collected during pelvic surgery.",[13],"Procedure: Biological Sample Collection",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","ACTIVE_COMPARATOR","Adult women without endometriosis undergoing collection of clinical data and biological samples, including blood, endometrial tissue, vaginal microbiota samples, and, when clinically indicated, additional samples collected during pelvic surgery.",[13],[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Biological Sample Collection","Collection of blood samples, endometrial samples, vaginal microbiota samples, and surgical specimens when clinically indicated for immunological and biomarker analyses.",[15,9],null,[27],{"name":28,"affiliation":29,"role":30},"Marie CARBONNEL, MD","Foch hospital","PRINCIPAL_INVESTIGATOR",[32],{"name":33,"role":34,"phone":35,"phoneExt":25,"email":36},"Florence Couppey, clinical project manager","CONTACT","+33 (0)1 46 25 31 30","f.couppey@hopital-foch.com",[38],{"facility":39,"status":25,"city":40,"state":25,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"Hôpital Foch","Suresnes","92150","France","FR",{"type":45,"coordinates":46},"Point",[47,48],2.22929,48.87143,{"lat":48,"lon":47},[51],{"name":52,"role":34,"phone":53,"phoneExt":25,"email":36},"Florence COUPPEY, Clinical project manager","+33(0)1 46 25 31 30",{"type":55,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100641783","interaction-between-decidual-cells-and-nk-cells-in-endometriosis-100641783",false,"NCT07652593","Interaction Between Decidual Cells and NK Cells in Endometriosis","Interaction Between Decidual Cells and Natural Killer Cells in Endometriosis: A Prospective Pilot Case-Control Study","PAINLESS","Inclusion Criteria:\n\n* Endometriosis Group\n* Female participant aged 18 years or older.\n* Confirmed diagnosis of deep endometriosis by imaging or surgery.\n* Pelvic pain and\u002For severe dysmenorrhea (Visual Analog Scale \\> 4).\n* Premenopausal.\n* No contraceptive or hormonal treatment during the study menstrual cycle.\n* Affiliated with a health insurance system.\n* Able and willing to provide written informed consent.\n* Control Group\n* Female participant aged 18 years or older.\n* No diagnosis of endometriosis.\n* Premenopausal.\n* No contraceptive or hormonal treatment during the study menstrual cycle.\n* No chronic pelvic pain or severe dysmenorrhea (Visual Analog Scale \\\u003C 4).\n* Affiliated with a health insurance system.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Current infection.\n* Active cancer.\n* Active autoimmune disease.\n* Concomitant hormonal treatment.\n* Pregnancy.\n* Participant under guardianship or legal protection.\n* Participant deprived of liberty.","FEMALE","18 Years",{"count":67,"type":68},50,"ESTIMATED","INTERVENTIONAL",[71],"NA","Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus and is frequently associated with pelvic pain and infertility. Increasing evidence suggests that immune dysfunction may contribute to the development and persistence of the disease.\n\nThe purpose of this prospective case-control study is to compare immune cell characteristics in women with deep endometriosis and women without endometriosis during the secretory phase of the menstrual cycle. Participants will undergo collection of clinical data, blood samples, endometrial samples, and vaginal microbiota samples. For participants undergoing clinically indicated pelvic surgery, additional biological samples may be collected during the procedure. The study aims to improve understanding of the immune mechanisms involved in endometriosis and to identify potential biomarkers associated with the disease.",[74],"Endometriosis",[74,76,77,78,79,80,81,82,83,84,85,86],"Deep Endometriosis","Natural Killer Cells","NK Cells","Endometrial Immune Microenvironment","CD39","Immunology","Vaginal Microbiota","Pelvic Pain","Cytokines","Women's Health","Biomarkers","NOT_YET_RECRUITING","2026-06-11",{"date":90,"type":91},"2026-06-17","ACTUAL",{"date":93,"type":68},"2026-06",{"date":95,"type":68},"2027-10",{"name":5,"class":6},1]