[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100580494":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":43,"centralContacts":55,"locations":63,"responsibleParty":103,"collaborators":105,"id":111,"slug":112,"hasResults":113,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":113,"sex":119,"minAge":120,"maxAge":121,"enrollmentInfo":122,"targetDuration":42,"studyType":125,"phases":126,"briefSummary":128,"conditions":129,"keywords":134,"overallStatus":139,"whyStopped":42,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":144,"completionDateStruct":146,"leadSponsor":148,"locationsCount":149},{"fullName":5,"class":6},"Al-Quds University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"External intercostal nerve block","EXPERIMENTAL","30 participants will be randomised for the External Intercostal block will receive a mixture of analgesics (Marcaine 3mg \u002Fkg 0.5%, Lidocaine 2% 10 cc, Dexamethasone 4 mg, 30 cc of Normal Saline (NS) 0.9%, through: Identifying the targeted intercostal spaces: The 3rd-7th by applying digital palpation and indentation of these spaces using the surgeon's fingers and the camera. After identifying the desired spaces, they will use 10 cc syringe connected to 23 Gauge needs, the needle will be applied externally into the chest wall, advancing it with negative pressure, making sure to keep the needle perpendicular to the chest wall to avoid injury to the intercostal neurovascular bundle, advancing the needle while keeping negative pressure, and being closer to the upper border of the ribs. Once the indentation of needle into the pleural is seen, they aspirate again to make sure that they are not into blood vessels, then they will inject 8 cc into each intercostal space.",[13],"Other: External Intercostal Nerve Block",{"label":15,"type":16,"description":17,"interventionNames":18},"Internal intercostal nerve block","ACTIVE_COMPARATOR","30 participants will be randomised for the Internal Intercostal block will receive a mixture of analgesics (the investigators will use a mixture of local analgesics containing: Marcaine 3mg \u002Fkg 0.5%, Lidocaine 2% 10 cc, Dexamethasone 4 mg, 30 cc of Normal Saline (NS) 0.9%), through:\n\n-Using the blue color butterfly needle, 23 gauge, The needle will be introduced into the thoracic cavity under the thoracoscopic control and vision, Identification of the intercostal spaces: The third down to the seventh, total of 5 intercostal spaces, the needle will be introduced under vision into the intercostal spaces, avoiding the intercostal artery or veins, aspiration to make sure that they are not into blood vessels, then 10 injecting 8 cc of the analgesic mixture into each of the intercostal spaces, making sure to see the pleura over the intercostal space bulging to indicate that the analgesic is not injected into deeper muscular layers.",[19],"Other: Internal Intercostal Nerve Block",{"label":21,"type":16,"description":22,"interventionNames":23},"Intercostal catheter","30 Participants will be randomised for the Intercostal Catheter, the investigators will use an epidural catheter set, they will apply the catheter to one - two intercostal spaces higher that the VATS incision. The investigators will start by applying the needle from outside, into the desired intercostal space, once they see the indentation of the needle. They will inject 5 - 10 cc of normal saline to distend the intercostal space, then they will remove the stylet part and they will introduce the catheter, after making sure that there is at least 3 centimeter of the catheter into the intercostal space, they will remove the needle, making sure not to move the catheter, then they will tunnel the catheter under the skin for 2 cm , the participant will receive the 15 cc of the previously mentioned mixture every 8 hours for two to three days.",[24],"Other: Intercostal Catheter",[26,32,38],{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"External Intercostal Nerve Block","External ICNB: A mixture of analgesics will be given through a needle inserted in the intercostal space from outside the chest wall.",[9],[31],"External ICNB",{"type":6,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"Internal Intercostal Nerve Block","Internal ICNB: A mixture of analgesics will be given through a needle inserted in the intercostal space inside the chest wall under direct thoracoscopic vision.",[15],[37],"Internal ICNB",{"type":6,"name":39,"description":40,"armGroupLabels":41,"otherNames":42},"Intercostal Catheter","Intercostal Catheter: it will be put 1-2 intercostal spaces above the VATS incision, and the participant will receive the 15 cc of the previously mentioned mixture every 8 hours for two to three days.",[21],null,[44,48,52],{"name":45,"affiliation":46,"role":47},"Yousef Abu Asabeh, M.D.","Thoracic Surgery Department, Al-Ahli Hospital, Palestine","STUDY_CHAIR",{"name":49,"affiliation":50,"role":51},"Mayar Idkedek, M.D.","Medical Research Club, Faculty of Medicine, Al-Quds University, Jerusalem, Palestine","STUDY_DIRECTOR",{"name":53,"affiliation":50,"role":54},"Tabarak Al-Masri, M.D.","PRINCIPAL_INVESTIGATOR",[56,60],{"name":45,"role":57,"phone":58,"phoneExt":42,"email":59},"CONTACT","+972592949192","dryousefabuasbeh@gmail.com",{"name":49,"role":57,"phone":61,"phoneExt":42,"email":62},"+972523172244","mayar.idkedek@gmail.com",[64,78],{"facility":65,"status":42,"city":66,"state":42,"zip":42,"country":67,"countryCode":42,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Saint Joseph Hospital","East Jerusalem","Palestinian Territories",{"type":69,"coordinates":70},"Point",[71,72],35.23388,31.78336,{"lat":72,"lon":71},[75,76,77],{"name":45,"role":57,"phone":58,"phoneExt":42,"email":59},{"name":49,"role":57,"phone":61,"phoneExt":42,"email":62},{"name":49,"role":54,"phone":42,"phoneExt":42,"email":42},{"facility":79,"status":42,"city":80,"state":42,"zip":42,"country":67,"countryCode":42,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Al-Ahli Hospital","Hebron",{"type":69,"coordinates":82},[83,84],35.0938,31.52935,{"lat":84,"lon":83},[87,88,89,90,93,95,97,99,101],{"name":45,"role":57,"phone":58,"phoneExt":42,"email":59},{"name":49,"role":57,"phone":61,"phoneExt":42,"email":62},{"name":53,"role":54,"phone":42,"phoneExt":42,"email":42},{"name":91,"role":92,"phone":42,"phoneExt":42,"email":42},"Alaaeddin Hliqawi, M.D.","SUB_INVESTIGATOR",{"name":94,"role":92,"phone":42,"phoneExt":42,"email":42},"Athar Mustafa",{"name":96,"role":92,"phone":42,"phoneExt":42,"email":42},"Tasneem Shalaan",{"name":98,"role":92,"phone":42,"phoneExt":42,"email":42},"Esraa Kurdi",{"name":100,"role":92,"phone":42,"phoneExt":42,"email":42},"Malik Itmaiza",{"name":102,"role":92,"phone":42,"phoneExt":42,"email":42},"Hadeel Ayesh, M.D.",{"type":104,"investigatorFullName":42,"investigatorTitle":42,"investigatorAffiliation":42,"oldNameTitle":42,"oldOrganization":42},"SPONSOR",[106,109],{"name":107,"class":108},"Al-Ahli Hospital, Hebron","UNKNOWN",{"name":110,"class":108},"Saint Joseph Hospital, East Jerusalem","100580494","intercostal-nerve-block-for-pain-management-after-uniportal-video-assisted-thoracoscopic-surgeries-100580494",false,"NCT06838026","Intercostal Nerve Block for Pain Management After Uniportal Video-assisted Thoracoscopic Surgeries","Internal, External Intercostal Nerve Block and Intercostal Catheter for Pain Management After Uniportal VATS: A Clinical Trial","VATS","Inclusion Criteria:\n\n* All participants between the ages of 18 and 80 year-old who have elective or urgent uniportal VATS will be included in the sample.\n\nExclusion Criteria:\n\n* Children - under the age of 18 or participants above the age of 80.\n* Participants with chest wall infections and those with decorticated lungs will be excluded from the study.\n* Participants with pre-existing chest pain or severe renal or hepatic dysfunction\n* Participants with a history of psychiatric disorder or inability to understand the consent form or how to use a Numerical Rating Scale (NRS) for pain measurement\n* Participants who have allergy to any of the given drugs, second thoracic surgery, participation in other clinical trials, obesity with body mass index\\>35 kg\u002Fm2, intake of antiplatelet or anticoagulant agents, spinal deformity and severe bradycardia will also be excluded.\n* Participants will be withdrawn from the study if the technical failure happened in the block or VATS procedure was converted to open procedure.","ALL","18 Years","80 Years",{"count":123,"type":124},90,"ESTIMATED","INTERVENTIONAL",[127],"NA","The goal of this clinical trial is to compare the safety and effectiveness of the three intercostal nerve blocks used in pain management in uniportal (one port) thoracoscopic surgeries: internal intercostal nerve blocks (ICNB), external ICNB, and Intercostal catheters.\n\nParticipants will be randomly assigned to three groups:\n\n* First group will undergo internal intercostal nerve block\n* Second group will be given external intercostal nerve block\n* Third group will have an intercostal catheter Researchers will compare the three groups to see their impact on post-operative pain management in uniportal VATS.",[130,131,132,133],"Thoracic","Pain, Postoperative","Analgesia","Satisfaction, Patient",[135,39,136,137,138],"Intercostal nerve block","Video-Assisted Thoracoscopic Surgery","Post-operative Pain","Patients' Satisfaction","NOT_YET_RECRUITING","2025-03-26",{"date":142,"type":143},"2025-04-01","ACTUAL",{"date":145,"type":124},"2025-05-05",{"date":147,"type":124},"2026-12-05",{"name":5,"class":6},2]