[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100473632":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":28,"centralContacts":33,"locations":39,"responsibleParty":48,"collaborators":24,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":24,"eligibilityCriteria":57,"healthyVolunteers":58,"sex":59,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":24,"studyType":65,"phases":66,"briefSummary":68,"conditions":69,"keywords":71,"overallStatus":42,"whyStopped":24,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Assaf-Harofeh Medical Center","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Hyperbaric Oxygen Therapy - HBOT","ACTIVE_COMPARATOR","The protocol comprises of 40 consecutive hyperbaric oxygen treatment (HBOT) sessions, 5 sessions per week within a two months' period. The HBOT group will train for 60 minutes after the HBOT sessions, 3 times per week, in a normobaric normoxic environment according to individualized training protocol",[13],"Device: Hyperbaric Oxygen Therapy - HBOT",{"label":15,"type":10,"description":16,"interventionNames":17},"Intermittent Hypoxic Training - IHT","The protocol comprises of 24 consecutive Intermittent Hypoxic Training (IHT) sessions, 3 sessions per week within a two months' period. Subjects will train according to individualized training protocol.",[18],"Device: Intermittent Hypoxic Training - IHT",[20,25],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":24},"DEVICE","Each session will include exposure of 90 minutes to 100% at 2 ATA, with 5 minutes air breaks every 20 minutes",[9],null,{"type":21,"name":15,"description":26,"armGroupLabels":27,"otherNames":24},"Each session lasts 60 minutes of 15.2% oxygen at 1.0 ATA. Subjects will be training according to individualized training protocol.",[15],[29],{"name":30,"affiliation":31,"role":32},"Shai a Efrati, MD","Asaf-Harofhe MC","PRINCIPAL_INVESTIGATOR",[34],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},"Shai Efrati, Prof","CONTACT","972-8-9779393","efratishai@outlook.com",[40],{"facility":41,"status":42,"city":43,"state":24,"zip":24,"country":44,"countryCode":45,"cosmosGeoPoint":24,"geoPoint":24,"contacts":46},"The Sagol Center for Hyperbaric Medicine and Research Shamir Medical Center (Assaf Harofeh)","RECRUITING","Zrifin","Israel","IL",[47],{"name":35,"role":36,"phone":37,"phoneExt":24,"email":38},{"type":32,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Shay Efrati","MD","100473632","intermittent-hypoxic-training-iht-versus-hyperbaric-oxygen-therapy-hbot-for-aerobic-performance-100473632",false,"NCT05447416","Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance","Intermittent Hypoxic Training (IHT) Versus Hyperbaric Oxygen Therapy (HBOT) for Aerobic Performance - Prospective Randomized Study","Inclusion Criteria:\n\n1. Vo2max above 3500 ml or Vo2max\u002Fkg above 50 ml\u002Fkg\n2. Age 18-45\n3. Subjects are active aerobic athletes, training regularly more than 4 exercise sessions per week.\n4. Subject willing and able to read, understand and sign an informed consent\n\nExclusion Criteria:\n\n1. Inability to attend scheduled clinic visits and\u002For comply with the study protocol\n2. Active malignancy\n3. Active smokers\n4. Previous treatment of HBOT for any reason prior to study enrollment.\n5. Chest pathology incompatible with pressure changes\n6. Major orthopedic injury at the past 3 months\n7. Inner ear disease\n8. Lung pathology\n9. The inability to perform an awake brain MRI\n10. Claustrophobia\n11. Previous neurologic conditions (e.g., Epilepsy, Brain tumors or s\u002Fp neurosurgery etc.)\n12. Comorbidities and medications that rule out the subject",true,"MALE","18 Years","45 Years",{"count":63,"type":64},66,"ESTIMATED","INTERVENTIONAL",[67],"NA","Comparing the effect of HBOT and IHT on aerobic performance of athletes.",[70],"Healthy Active Athletes",[72,73,74,75,76,77],"triathletes","cyclists","mitochondria","HBOT","HBO","IHT","2026-04-16",{"date":80,"type":81},"2026-04-21","ACTUAL",{"date":83,"type":81},"2023-06-01",{"date":85,"type":64},"2027-12-31",{"name":5,"class":6},1]