[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618717":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":35,"responsibleParty":50,"collaborators":11,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":11,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":11,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":74,"overallStatus":37,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Konya City Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Block Group - Intertransverse Process Block","ACTIVE_COMPARATOR",null,[13],"Procedure: Intertransverse Process Block",{"label":15,"type":16,"description":11,"interventionNames":17},"Control Group - Placebo:","PLACEBO_COMPARATOR",[18],"Procedure: Placebo",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"PROCEDURE","Intertransverse Process Block","The block will be performed under ultrasound guidance by the same anesthesiologist with more than five years of experience, immediately after surgery and before emergence from anesthesia. Patients will be placed in the lateral decubitus position with the operative side uppermost and the skin prepared.\n\nUsing a high-frequency linear probe (Mindray DC-60 Exp), the T5 spinous process will be identified at the midline, then the probe will be moved approximately 2 cm laterally to visualize the superior costotransverse ligament (SCTL) and pleura. The needle will be advanced in-plane in a caudal-to-cranial direction toward the cranial border of the fourth rib. After confirmation of correct spread by hydrodissection, 20 mL of 0.5% bupivacaine will be injected.",[9],{"type":21,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Placebo","In the control group, the same procedure will be conducted, but saline will be injected instead of local anesthetic.",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"Omer Keklicek, Principal Investigator","CONTACT","+905399291702","drokeklicek@gmail.com",[36],{"facility":5,"status":37,"city":38,"state":11,"zip":11,"country":39,"countryCode":11,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Konya","Turkey (Türkiye)",{"type":41,"coordinates":42},"Point",[43,44],32.48464,37.87135,{"lat":44,"lon":43},[47],{"name":31,"role":32,"phone":48,"phoneExt":11,"email":49},"+90 332 223 70 00","hastane@erbakan.edu.tr",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Ömer Keklicek","principal investigator","100618717","intertransverse-process-block-for-postoperative-analgesia-after-thoracotomy-and-lobectomy-100618717",false,"NCT07335250","Intertransverse Process Block for Postoperative Analgesia After Thoracotomy and Lobectomy","Postoperative Pain Control With Intertransverse Process Block in Patients Undergoing Thoracotomy With Lobectomy","Inclusion Criteria:\n\n* Provision of written informed consent\n\nAge between 18 and 85 years\n\nASA Physical Status classification I-III\n\nElective thoracotomy with planned unilateral lobectomy\n\nAnticipated hospital stay of at least one night\n\nExpected requirement for parenteral opioid analgesia for at least 24 hours postoperatively\n\nAbility to operate an intravenous patient-controlled analgesia (PCA) device\n\nExclusion Criteria:\n\n* Patients undergoing emergency surgery\n\nPresence of infection or open wound at the injection site\n\nCoagulopathy\n\nHepatic or renal failure\n\nPatients undergoing reoperation\n\nPatients with missing or incomplete data\n\nPregnancy or lactation\n\nTracheal malformation or tracheostomy\n\nChronic opioid use (≥30 days within the last 3 months, ≥15 mg\u002Fday morphine equivalent)\n\nPatients exceeding the maximum safe local anesthetic dose based on weight (2.5 mg\u002Fkg, max 150 mg)\n\nPatients who refuse data privacy consent will be excluded from the study","ALL","18 Years","85 Years",{"count":65,"type":66},66,"ESTIMATED","INTERVENTIONAL",[69],"NA","This prospective, randomized, triple-blind, placebo-controlled clinical trial will investigate the effectiveness of the intertransverse process block (ITPB) for postoperative analgesia in patients undergoing elective thoracotomy with unilateral lobectomy. The study will be conducted at a single tertiary center in accordance with the principles of the Declaration of Helsinki, and written informed consent will be obtained from all participants.\n\nPatients will be randomized in a 1:1 ratio to receive either ultrasound-guided ITPB with 0.5% bupivacaine or placebo (normal saline) prepared in identical syringes to ensure allocation concealment. The block will be performed by an experienced anesthesiologist immediately after surgery and before emergence from anesthesia. Both groups will receive standardized general anesthesia, multimodal perioperative analgesia, and postoperative intravenous morphine patient-controlled analgesia (PCA).\n\nThe trial aims to evaluate the analgesic efficacy and opioid-sparing effect of ITPB while maintaining safety and adherence to routine clinical practice. Outcomes will include postoperative pain scores, opioid consumption, rescue analgesia requirement, and adverse events.",[72,73,22],"Acute Postoperative Pain","Thoracotomy Surgery",[22,75,72],"Thoracotomy Lobectomy","2026-04-08",{"date":78,"type":79},"2026-04-09","ACTUAL",{"date":76,"type":79},{"date":82,"type":66},"2027-03-01",{"name":5,"class":6},1]