[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100641947":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":26,"locations":11,"responsibleParty":32,"collaborators":11,"id":36,"slug":37,"hasResults":38,"nctId":39,"briefTitle":40,"officialTitle":41,"acronym":11,"eligibilityCriteria":42,"healthyVolunteers":38,"sex":43,"minAge":44,"maxAge":45,"enrollmentInfo":46,"targetDuration":11,"studyType":49,"phases":50,"briefSummary":52,"conditions":53,"keywords":58,"overallStatus":61,"whyStopped":11,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":11},{"fullName":5,"class":6},"Antalya City Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intertransverse Process Block","ACTIVE_COMPARATOR",null,[13],"Procedure: Intertransverse Process Block",{"label":15,"type":10,"description":11,"interventionNames":16},"M-TAPA Block",[17],"Procedure: M-TAPA Block",[19,23],{"type":20,"name":9,"description":21,"armGroupLabels":22,"otherNames":11},"PROCEDURE","A linear ultrasound probe will be positioned along the medial border of spinous processes level of the T7\u002FT8 thoracic vertebrae.Anatomical landmarks, including the erector spinae muscle, transverse processes, and superior costotransverse ligament complex at the T7\u002FT8 level, will be identified. Using an in-plane approach, a 21 G 0.8x100 mm echogenic insulated needle will be inserted through the erector spinae muscle toward the intertransverse tissue complex located between the superior costotransverse ligament and the transverse processes. Proper needle placement will be confirmed with the injection of 1-2 mmL isotonic saline demonstrating separation within the intertransverse plane. Upon confirmation and negative aspiration, 20 mL of 0.25% bupivacaine hydrochloride will be administered on each side under ultrasound guidance.",[9],{"type":20,"name":15,"description":24,"armGroupLabels":25,"otherNames":11},"A linear ultrasound probe will be positioned obliquely along the costal margin at the level of the 10th costal cartilage. Anatomical landmarks, including the costal cartilage, rectus abdominis muscle, transversus abdominis muscle, and internal oblique muscle will be identified. Using an in-plane approach, a 21G 0.8×100 mm echogenic insulated needle will be inserted toward the perichondrial plane beneath the 10th costal cartilage under ultrasound guidance. Proper needle placement will be confirmed with the injection of 1-2 mL isotonic saline. Upon confirmation and negative aspiration, 20 mL of 0.25% bupivacaine hydrochloride will be administered on each side under ultrasound guidance.",[15],[27],{"name":28,"role":29,"phone":30,"phoneExt":11,"email":31},"MUSTAFA KILIN, CONSULTANT İN ANESTHESİOLOGY","CONTACT","+905464569218","mustafa.kilin90@gmail.com",{"type":33,"investigatorFullName":34,"investigatorTitle":35,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Mustafa Kılın","CONSULTANT ANESTHESİOLOGİST","100641947","intertransverse-process-block-versus-m-tapa-block-after-laparoscopic-cholecystectomy-100641947",false,"NCT07589491","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy","Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients aged 18-65 years\n* ASA physical status I-III\n* Scheduled for elective laparoscopic sleeve gastrectomy\n* Body mass index (BMI) 18-35 kg\u002Fm²\n* Ability to understand and use the patient-controlled analgesia (PCA) device\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Refusal to participate\n* Allergy to local anesthetics\n* Infection at the injection site\n* Coagulopathy or ongoing anticoagulant therapy\n* Chronic opioid use or opioid dependence\n* Severe hepatic or renal insufficiency\n* Pregnancy or breastfeeding\n* Cognitive impairment or inability to communicate pain scores\n* Body mass index (BMI) \\>35 kg\u002Fm²","ALL","18 Years","65 Years",{"count":47,"type":48},60,"ESTIMATED","INTERVENTIONAL",[51],"NA","This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. The primary outcome is the Visual Analog Scale (VAS) score within the first 24 hours after surgery. Secondary outcomes include total opioid consumption, requirement for rescue analgesia, block- related complications and adverse effects (hematoma, pneumothorax, local anesthetic systemic complications, vascular puncture, and infection), patient satisfaction assessed using a Likert scale, quality of recovery assessed using the QoR-15 questionnaire, and incidence of postoperative nausea and vomiting.",[9,54,55,56,57],"Mtapa Block","Laparoscopic Cholecystectomy","Postoperative Pain","Regional Anaesthesia",[59,60],"M-TAPA","ITP","NOT_YET_RECRUITING","2026-06-15",{"date":64,"type":65},"2026-06-16","ACTUAL",{"date":67,"type":48},"2026-11-15",{"date":69,"type":48},"2027-10-30",{"name":5,"class":6}]