[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607656":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":61,"collaborators":26,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":69,"acronym":26,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":26,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":26,"overallStatus":40,"whyStopped":26,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"The Second Hospital of Anhui Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"real stimulation","ACTIVE_COMPARATOR","Participants will receive active TIS 10 to 14 times.",[13],"Device: Temporal Interference Stimulation (TIS)",{"label":15,"type":16,"description":17,"interventionNames":18},"sham stimulation","SHAM_COMPARATOR","Participants will receive sham TIS 10 to 14 times.",[19],"Device: Sham temporal interference stimulation (TIS)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","Temporal Interference Stimulation (TIS)","The total stimulation duration was 30 minutes, including a 30-second current ramp-up at the beginning and a 30-second ramp-down at the end.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Sham temporal interference stimulation (TIS)","Sham stimulation had only 30 seconds of current ramping-up and ramping-down at the beginning and end of the stimulation, respectively, to simulate the sensation of actual stimulation",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Yanghua Tian, PhD","CONTACT","0551 6599 7278","zylykd@163.com",[38,54],{"facility":39,"status":40,"city":41,"state":42,"zip":26,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Anhui Medical University","RECRUITING","Hefei","Anhui","China","CN",{"type":46,"coordinates":47},"Point",[48,49],117.28083,31.86389,{"lat":49,"lon":48},[52],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":53},"ayfytyh@126.com",{"facility":55,"status":40,"city":41,"state":42,"zip":26,"country":43,"countryCode":44,"cosmosGeoPoint":56,"geoPoint":58,"contacts":59},"Anhui Mental Health Center",{"type":46,"coordinates":57},[48,49],{"lat":49,"lon":48},[60],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":53},{"type":62,"investigatorFullName":63,"investigatorTitle":64,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Yanghua Tian","Vice President of Anhui Medical University","100607656","intervention-effect-of-temporal-interference-stimulation-tis-on-depressive-disorder-100607656",false,"NCT07191392","Intervention Effect of Temporal Interference Stimulation (TIS) on Depressive Disorder","Inclusion Criteria:\n\n* the patients were diagnosed by more than 2 psychiatrists and met the diagnostic criteria of DSM-5 for depression, and HAMD\\>17, BSS\\>6, PHQ-15\\>5.\n* the age ranged from 18 to 65 years old, and the length of education was more than 5 years.\n* the visual acuity or corrected visual acuity is normal, right-handed, can cooperate with the completion of various experimental tests.\n\nExclusion Criteria:\n\n* accompanied by severe somatic diseases, such as severe heart, liver, renal insufficiency and so on.\n* accompanied by other neurological diseases, such as stroke, epilepsy and so on. pregnant and lactating women.\n* accompanied by other mental disorders, such as drug abuse, schizophrenia, schizophrenic affective",true,"ALL","12 Years","60 Years",{"count":76,"type":77},60,"ESTIMATED","INTERVENTIONAL",[80],"NA","To investigate the effect of Temporal Interference Stimulation (TIS) on associative memory (AM) in patients with depressive disorder",[83,84],"Depressive Disorder","Temporal Interference Stimulation","2026-03-09",{"date":87,"type":88},"2026-03-10","ACTUAL",{"date":90,"type":88},"2025-09-01",{"date":92,"type":77},"2026-06",{"name":5,"class":6},2]