[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550740":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":56,"collaborators":59,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":12,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":12,"enrollmentInfo":72,"targetDuration":12,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":85,"overallStatus":40,"whyStopped":12,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Medical University of South Carolina","OTHER",[8,13],{"label":9,"type":10,"description":11,"interventionNames":12},"Control","NO_INTERVENTION","For each surgeon cluster this will be the time period prior to initiation of the intervention during which time we will assess contemporary baseline rate of guideline concordant utilization of extended pharmacologic venous thromboembolism prophylaxis.\n\nFor patients, this will include survey responses prior to use of dedicated discharge education on venous thromboembolism and prophylaxis strategies.",null,{"label":14,"type":15,"description":16,"interventionNames":17},"Intervention","EXPERIMENTAL","For each cluster this will be the time period after initiation of the intervention during which time we will assess the rate of guideline concordant utilization of extended pharmacologic venous thromboembolism prophylaxis with dedicated education and the use of an electronic medical record based clinical decision support system.\n\nFor patients, this will include survey responses after use of dedicated discharge education on venous thromboembolism and prophylaxis strategies.",[18],"Behavioral: Exposure to clinical decision support system and education",[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":12},"BEHAVIORAL","Exposure to clinical decision support system and education","Surgeons will receive education regarding post-discharge venous thromboembolism after cancer surgery. An electronic medical record based decision support tool with be initiated that will identify patients who have undergone major abdominopelvic cancer surgery. The tool will permit use of a risk stratification score and advise guideline concordant post-discharge venous thromboembolism prophylaxis strategies.\n\nPatients will receive dedicated venous thromboembolism education at the time of discharge.",[14],[26],{"name":27,"affiliation":5,"role":28},"Thomas Curran, MD MPH","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":12,"email":33},"CONTACT","843-876-4846","currant@musc.edu",{"name":35,"role":31,"phone":36,"phoneExt":12,"email":37},"Brett Bechtol","843-792-6659","bechtolb@musc.edu",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Charleston","South Carolina","29425","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-79.93275,32.77632,{"lat":50,"lon":49},[53,54,55],{"name":27,"role":31,"phone":32,"phoneExt":12,"email":33},{"name":35,"role":31,"phone":36,"phoneExt":12,"email":37},{"name":27,"role":28,"phone":12,"phoneExt":12,"email":12},{"type":28,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":12,"oldOrganization":12},"Thomas Curran","Associate Professor-Faculty",[60],{"name":61,"class":62},"National Cancer Institute (NCI)","NIH","100550740","intervention-to-improve-utilization-of-extended-venous-thromboembolism-prophylaxis-after-cancer-surgery-100550740",false,"NCT06451003","Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery","An Equity Focused Intervention to Improve Utilization of Guideline Concordant Extended Venous Thromboembolism Prophylaxis After Major Cancer Surgery","SURGEON CLUSTER\n\nInclusion Criteria:\n\n* Surgeons performing cancer surgery within the Medical University of South Carolina (MUSC) system will be identified. Patients undergoing surgery for included cancers in the three hospitals will be identified using inclusion\u002Fexclusion criteria as follows. \"Abdominopelvic cancer surgery\" includes esophagectomy, gastrectomy, pancreatectomy, small bowel resection, colectomy, proctectomy, cystectomy, nephrectomy and hysterectomy \u002F oophorectomy performed for a diagnosis of cancer as identified by Current Procedural Terminology (CPT) code and International Classification of Diseases, Tenth Revision (ICD-10) diagnosis code.\n\nExclusion Criteria:\n\n* We will exclude patients receiving preoperative therapeutic anticoagulation within 30 days preoperatively, patients initiating therapeutic anticoagulation postoperatively and patients with chronic kidney disease grade 3 or higher. Patients with postoperative length of stay 30 days or greater will be excluded as ePpx duration is for 30 days postoperative.\n\nPATIENT SURVEY\n\nInclusion Criteria:\n\n* Patients undergoing surgery for included cancers in the three hospitals will be identified using inclusion\u002Fexclusion criteria as follows. \"Abdominopelvic cancer surgery\" includes esophagectomy, gastrectomy, pancreatectomy, small bowel resection, colectomy, proctectomy, cystectomy, nephrectomy and hysterectomy \u002F oophorectomy performed for a diagnosis of cancer as identified by Current Procedural Terminology (CPT) code and International Classification of Diseases, Tenth Revision (ICD-10) diagnosis code.\n\nExclusion Criteria:\n\n* We will exclude patients receiving preoperative therapeutic anticoagulation within 30 days preoperatively, patients initiating therapeutic anticoagulation postoperatively and patients with chronic kidney disease grade 3 or higher. Patients with postoperative length of stay 30 days or greater will be excluded as extended pharmacologic venous thromboembolism duration is for 30 days postoperative.\n* Lack of survey response.","ALL","18 Years",{"count":73,"type":74},30,"ESTIMATED","INTERVENTIONAL",[77],"NA","While blood clots after major cancer surgery are common and harmful to patients, the medications to decrease blood clot risk are seldom used after patients leave the hospital despite the recommendation of multiple professional medical societies. The reason why these medications are seldom prescribed is not well understood. The main questions this study aims to answer are:\n\n* Does surgeon education paired with an electronic medical record based decision support tool improve the guideline concordant prescription of pharmacologic venous thromboembolism after abdominopelvic cancer surgery?\n* Does dedicated patient education regarding blood clots at the time of hospital discharge after abdominopelvic cancer surgery improve understanding of the risk of venous thromboembolism and adherence to pharmacologic prophylaxis?\n\nThe investigators will study these questions using a stepped-wedge randomized trial where groups of surgeons will use a tool integrated to the electronic medical record to educate them on the individualized patient risks of blood clots after major cancer surgery and inform them regarding guidelines for preventative medicines. Utilization of the medications before and after using the tool will be compared.\n\nPatients will be administered a questionnaire assessing their awareness of blood clots as a risk after cancer surgery. For those prescribed medications to reduce blood clot risk after leaving the hospital, the questionnaire will evaluate whether they took the medications as prescribed. Survey results will be evaluated before and after implementation of education on blood clot risk at the time of hospital discharge.",[80,81,82,83,84],"Venous Thromboembolism","Pulmonary Embolism","Deep Vein Thrombosis","Cancer","Surgery",[86,87,88,89,90,91],"venous thromboembolism","pulmonary embolism","deep vein thrombosis","cancer","surgery","clinical decision support system","2025-07-28",{"date":94,"type":95},"2025-07-31","ACTUAL",{"date":97,"type":95},"2024-07-01",{"date":99,"type":74},"2026-12-31",{"name":5,"class":6},1]