[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100560880":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":36,"locations":41,"responsibleParty":59,"collaborators":62,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":68,"sex":74,"minAge":75,"maxAge":76,"enrollmentInfo":77,"targetDuration":26,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":86,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of California, Los Angeles","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Cognitive Training","EXPERIMENTAL","Computer Based Cognitive Training (CT) Programs delivered in a group setting using the Neuropsychological Educational Approach to Cognitive Remediation (NEAR) model.",[13],"Behavioral: Cognitive training (CT) plus the neuropsychological educational approach to cognitive remediation (NEAR) model and an Enhanced - Treatment as Usual (E-TAU)",{"label":15,"type":16,"description":17,"interventionNames":18},"Enhanced Treatment as Usual","ACTIVE_COMPARATOR","Enhanced Treatment as Usual (E-TAU) sessions are delivered in a group therapy format and guided by the principles of Cognitive Behavioral Therapy (CBT). The E-TAU sessions focus on helping individuals identify and change negative thought patterns and behaviors that contribute to emotional distress and mental health issues.",[19],"Behavioral: Enhanced - Treatment as Usual",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Cognitive training (CT) plus the neuropsychological educational approach to cognitive remediation (NEAR) model and an Enhanced - Treatment as Usual (E-TAU)","Psychosocial interactions computer-based cognitive training (CT) administered in a group setting that includes the Neuropsychological Educational Approach to Cognitive Remediation (NEAR) model:",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Enhanced - Treatment as Usual","The Enhanced-Treatment as Usual (E-TAU) sessions are delivered in a group therapy format and guided by the principles of Cognitive Behavioral Therapy (CBT). Participants learn to develop coping skills and are educated on how to improve distortions to reduce anxiety and depression.",[15],[32],{"name":33,"affiliation":34,"role":35},"Joseph Ventura, Ph.D.","UCLA Department of Psychiatry & Biobehavioral Sciences","PRINCIPAL_INVESTIGATOR",[37],{"name":33,"role":38,"phone":39,"phoneExt":26,"email":40},"CONTACT","310-245-2811","jventura@mednet.ucla.edu",[42],{"facility":43,"status":44,"city":45,"state":26,"zip":26,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Razi University Hospital","RECRUITING","Tunis","Tunisia","TN",{"type":49,"coordinates":50},"Point",[51,52],10.16579,36.81897,{"lat":52,"lon":51},[55],{"name":56,"role":38,"phone":57,"phoneExt":26,"email":58},"Uta Ouali, M.D.","+216 716 00 154","uta.ouali@gmail.com",{"type":35,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Ventura, Joseph","Principal Investigator",[63],{"name":64,"class":65},"National Institute of Mental Health (NIMH)","NIH","100560880","interventions-for-clinical-high-risk-youth-in-tunisia-100560880",false,"NCT06582901","Interventions for Clinical High Risk Youth in Tunisia","Cognitive Training vs. Treatment as Usual to Improve Functioning and Reduce Transition Rates in Tunisian CHR Youth: A Feasibility Study","CHRTUNISIA","Inclusion Criteria:\n\n* Meets Comprehensive Assessment for At Risk Mental States (CAARMS) criteria for Clinical High Risk\n* If under the age of 18, the subject has a parent or guardian who can sign consent forms\n* Premorbid Intelligence Quotient not less than 70\n* Sufficient fluency in Arabic, French, or English to avoid invalidating research measures\n* Residence likely within commuting distance of Razi University Hospital\n\nExclusion Criteria:\n\n* Evidence of known neurological disorder, e.g. epilepsy or significant head injury that could account for the CHR symptoms\n* Evidence of significant and habitual alcohol or substance use in the 6 months prior to study entry\n* Evidence that the clinical high-risk symptoms were substance-induced","ALL","14 Years","28 Years",{"count":78,"type":79},54,"ESTIMATED","INTERVENTIONAL",[82],"NA","Study participants will take part in one of the two types of treatments aimed at improving daily functioning as follows: either a Cognitive Training (CT) Program or an Enhanced - Treatment as Usual (E-TAU) Group. All group treatments will be provided at Razi Hospital and one of the sessions will be conducted at home. The Cognitive (thinking skills) Training and Neuropsychological Education Approach to Remediation (CT-NEAR) is a form of cognitive (thinking skills) training that consists of computer-game like brain exercises, learning about thinking skills strategies, and a \"bridging group\" to help participants use what is learned in daily life. Cognitive exercises are generally fun and playful and are done on a computer. The aim is to train thinking skills and ability to function better in daily life such as at school, university, or at work, or with friends and family. The program lasts 12 weeks with two weekly sessions in groups of 3 to 4 participants. Each session is 1½ hours in length and one of the sessions is which lasts 30 minutes is conducted at home using a tablet that will be provided by the study investigators.",[85],"Clinical High Risk for Psychosis (CHR)",[87,88,89,90],"clinical High Risk youth","cognitive training","enhanced treatment as usual","transition to psychosis","2025-11-21",{"date":93,"type":94},"2025-11-25","ACTUAL",{"date":96,"type":94},"2023-09-01",{"date":98,"type":79},"2026-08-31",{"name":5,"class":6},1]