[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565363":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":34,"responsibleParty":55,"collaborators":25,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":25,"eligibilityCriteria":65,"healthyVolunteers":61,"sex":66,"minAge":67,"maxAge":68,"enrollmentInfo":69,"targetDuration":25,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":25,"overallStatus":36,"whyStopped":25,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Tanta University","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Group 1","ACTIVE_COMPARATOR","A group of Patients from Tanta University suffering from Chronic painful knee osteoarthritis who didn't receive medical treatment and progressed to have chronic pain with decreased physical function and poorer quality of life.",[13,14],"Drug: Triamcinolone Acetonide","Drug: Bupivacaine Hydrochloride",{"label":16,"type":10,"description":11,"interventionNames":17},"Group 2",[18],"Drug: Dexmedetomidine",[20,26,30],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","Triamcinolone Acetonide","1 ml of triamcinolone acetonide was used to prepare a solution for knee injection for patients with Chronic Knee Pain",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Bupivacaine Hydrochloride","20mg of bupivacaine hydrochloride was used to prepare a solution for knee injection for patients with Chronic Knee Pain",[9],{"type":21,"name":31,"description":32,"armGroupLabels":33,"otherNames":25},"Dexmedetomidine","Dexmedetomidine solution was prepared by mixing Dexmedetomidine in a dose of 3 µg\u002Fkg in 5-ml saline",[16],[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Tanta","El Gharbyia","13511","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.00192,30.78847,{"lat":46,"lon":45},[49],{"name":50,"role":51,"phone":52,"phoneExt":53,"email":54},"Ali El Deeb, Professor","CONTACT","01222800335","+2","b.checked88@gmail.com",{"type":56,"investigatorFullName":57,"investigatorTitle":58,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Ahmed ElKashef","lecturer of Anesthesia and Surgical ICU, Faculty of Medicine","100565363","intra-articular-dexmedetomidine-a-treatment-for-chronic-knee-pain-100565363",false,"NCT06641206","Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain","Intra-articular Dexmedetomidine for Treatment of Chronic Knee Pain: A Prospective Case-Control Clinical Trial","Inclusion Criteria:\n\n* Patients were not assigned for surgical intervention;\n* Patients were free of exclusion criteria\n\nExclusion Criteria:\n\n* Patients were assigned for surgical intervention;\n* Patients who had uncontrolled hypertension and\u002For diabetes mellitus;\n* Patients who had uncompensated cardiac, renal, or hepatic diseases;\n* Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs;\n* Patients who refused to sign the informed consent were excluded from the study.","ALL","40 Years","75 Years",{"count":70,"type":71},70,"ESTIMATED","INTERVENTIONAL",[74],"NA","Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to anesthesia and local anesthetics. Given its potential for pain management, exploring DEX as a treatment for KOA could offer a new and promising approach.",[77],"Chronic Knee Pain","2024-10-11",{"date":80,"type":81},"2024-10-15","ACTUAL",{"date":83,"type":81},"2024-09-17",{"date":85,"type":71},"2025-03",{"name":5,"class":6},1]