[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100579921":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":45,"centralContacts":49,"locations":59,"responsibleParty":85,"collaborators":54,"id":88,"slug":89,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":54,"eligibilityCriteria":94,"healthyVolunteers":95,"sex":96,"minAge":97,"maxAge":54,"enrollmentInfo":98,"targetDuration":54,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":108,"overallStatus":62,"whyStopped":54,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A: Aminophylline Group: Intra-ureteric instillation of aminophylline","EXPERIMENTAL","a ureteric catheter 6 Fr will be used for instillation of normal saline supplemented with aminophylline 250 mg\u002F10 mL at three points (Pelvi-ureteric junction, upper sacroiliac joint level and proximal to uretero-vesical junction by 5 cm) then wait for 5 minutes",[13],"Drug: Usage of Aminophylline prior to ureteric dilatation in Flexible uretroscopy",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B: Ureteral Dilator Group: Traditional ureteral dilators","ACTIVE_COMPARATOR","traditional ureteral dilators will be used. We will start by ureteral dilator 6 fr and gradually increase the size up to 12 Fr",[19],"Device: Sequential teflon dilator usage prior to ureteric access sheath placement in flexible uretroscopy",{"label":21,"type":6,"description":22,"interventionNames":23},"Group C: Combination Group: Aminophylline instillation and Ureteral dilators","Aminophylline will be instilled as in group (A) then followed by traditional ureteral dilatation as in group (B)",[13,19,24],"Other: Aminophylline instillation and Ureteral dilators together",[26,33,39],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Usage of Aminophylline prior to ureteric dilatation in Flexible uretroscopy","Intraureteric aminophylline installation prior to ureteric dilatation",[9,21],[32],"Intraureteric Aminophylline instillation prior to access sheath insertion",{"type":34,"name":35,"description":17,"armGroupLabels":36,"otherNames":37},"DEVICE","Sequential teflon dilator usage prior to ureteric access sheath placement in flexible uretroscopy",[15,21],[38],"ureteric teflon dilators prior to access sheath insertion",{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":43},"Aminophylline instillation and Ureteral dilators together","Aminophylline will be instilled as in group (A) then followed by traditional ureteral dilatation as in group (B) prior to placing the ureteric access sheath",[21],[44],"combination of aminophylline instillation and ureteric teflon dilators prior to access sheath insertion",[46],{"name":47,"affiliation":5,"role":48},"Younan Samir, PhD","PRINCIPAL_INVESTIGATOR",[50,56],{"name":51,"role":52,"phone":53,"phoneExt":54,"email":55},"Ali Khaled Mohammed Ali Dr. Ali Khaled, MSc.","CONTACT","+201099978174",null,"ali.khaled94@gmail.com",{"name":47,"role":52,"phone":57,"phoneExt":54,"email":58},"+201201255511","dr_yona@live.com",[60],{"facility":61,"status":62,"city":63,"state":64,"zip":65,"country":66,"countryCode":67,"cosmosGeoPoint":68,"geoPoint":73,"contacts":74},"Ain Shams University Hospitals","RECRUITING","Cairo","Abassia","11517","Egypt","EG",{"type":69,"coordinates":70},"Point",[71,72],31.24967,30.06263,{"lat":72,"lon":71},[75,78,81,83],{"name":76,"role":52,"phone":77,"phoneExt":54,"email":55},"Ali Khaled Mohammed Ali M. Dr. Ali Khaled, MSc.","201099978174",{"name":79,"role":52,"phone":80,"phoneExt":54,"email":54},"Younan R. Lecturer Dr. Younan Ramsis Samir, PhD.","201255511",{"name":82,"role":48,"phone":54,"phoneExt":54,"email":54},"Younan R. Samir, PhD.",{"name":84,"role":48,"phone":54,"phoneExt":54,"email":54},"Mahmoud A. Dr. Mahmoud Ahmed, PhD.",{"type":48,"investigatorFullName":86,"investigatorTitle":87,"investigatorAffiliation":5,"oldNameTitle":54,"oldOrganization":54},"Younan Ramsis","Lecturer of Urology","100579921","intra-ureteric-aminophylline-instillation-on-flexible-ureteroscopy-procedure-100579921",false,"NCT06830577","Intra-ureteric Aminophylline Instillation on Flexible Ureteroscopy Procedure","Efficacy of Intra-ureteric Aminophylline Instillation on Flexible Ureteroscopy Procedure: A Randomized Controlled Study","Inclusion Criteria:\n\n* Upper ureteric stones or renal stones \\\u003C 2 cm\n\nExclusion Criteria:\n\n1. Ureteric strictures.\n2. anatomic renal disorders\n3. functional renal disorders\n4. Urinary tract infection.\n5. Coagulopathy and uncorrected bleeding disorders.\n6. Prior DJ stenting\n7. any contraindication for aminophylline use: (hypersensitivity to theophylline, ethylenediamine, or any component of the drug formulation, pregnancy or lactation, active peptic ulcer, presence of cardiologic diseases, presence of neurologic diseases, presence of renal impairment and presence of hepatic dysfunction)",true,"ALL","18 Years",{"count":99,"type":100},129,"ESTIMATED","INTERVENTIONAL",[103],"NA","in this study we are going to evaluate the efficacy of intra-ureteric aminophylline instillation in facilitating ureteric access sheath placement prior to flexible ureteroscopy in reducing ureteric injury rates.",[106,107],"Stones, Kidney","Ureteric Injury",[109,110,111,112],"Aminophylline","Ureteric access sheath","ureteric injury","Flexible Uretroscopy","2025-06-10",{"date":115,"type":116},"2025-06-12","ACTUAL",{"date":118,"type":116},"2025-03-01",{"date":120,"type":100},"2026-02-01",{"name":5,"class":6},1]