[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100502425":3},{"organization":4,"armGroups":7,"interventions":50,"overallOfficials":84,"centralContacts":88,"locations":93,"responsibleParty":108,"collaborators":56,"id":111,"slug":112,"hasResults":113,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":113,"sex":119,"minAge":120,"maxAge":121,"enrollmentInfo":122,"targetDuration":56,"studyType":125,"phases":126,"briefSummary":128,"conditions":129,"keywords":56,"overallStatus":95,"whyStopped":56,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":140},{"fullName":5,"class":6},"Medical University of Vienna","OTHER",[8,14,18,22,26,30,34,38,42,46],{"label":9,"type":10,"description":11,"interventionNames":12},"Monofocal IOL I vs. enhanced monofocal IOL I","EXPERIMENTAL","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm one (I) participants will receive a monofocal IOL (ZCB00) vs. an enhanced monofocal IOL (ICB00)",[13],"Procedure: phacoemulsification and intraocular lens implantation",{"label":15,"type":10,"description":16,"interventionNames":17},"Monofocal IOL II vs. enhanced monofocal IOL I","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm two (II) participants will receive a monofocal IOL (Sensar 1AAB00) vs. an enhanced monofocal IOL (ICB00)",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Monofocal IOL III vs. enhanced monofocal IOL II","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm three (III) participants will receive a monofocal IOL (Vivinex XY1)vs. an enhanced monofocal IOL (Vivinex Impress).",[13],{"label":23,"type":10,"description":24,"interventionNames":25},"Enhanced monofocal IOL II vs. enhanced monofocal IOL II","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm four (IV) participants will receive an enhanced monofocal IOL (Vivinex Impress) bilateral with a monovision target",[13],{"label":27,"type":10,"description":28,"interventionNames":29},"Monofocal IOL IV vs. enhanced monofocal IOL III","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm five (V) participants will receive an enhanced monofocal IOL (EnVista) vs. an enhanced monofocal IOL (LuxSmart)",[13],{"label":31,"type":10,"description":32,"interventionNames":33},"Extended depth of focus IOL IV in eyes with low to moderate irregular astigmatism","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm six (VI) participants will receive an extended depth of focus IOL (Acrysof IQ Vivity) in both eyes if low to moderate irregular astigmatism is observed.",[13],{"label":35,"type":10,"description":36,"interventionNames":37},"Extended Depth of Focus IOL in eyes with irregular astigmatism","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm seven (VII) participants will receive an extended depth of focus IOL (IC-8 Apthera IOL) in one eye if irregular astigmatism is observed.",[13],{"label":39,"type":10,"description":40,"interventionNames":41},"Monofocal IOL IV vs. enhanced monofocal IOL IV","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm eight (VIII) participants will receive an enhanced monofocal IOL (EnVista) vs. an enhanced monofocal IOL (EnVista Aspire)",[13],{"label":43,"type":10,"description":44,"interventionNames":45},"Enhanced depth of focus IOL I vs. Enhanced depth of focus IOL I","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm nine (IX) participants will receive an enhanced depth of focus IOL (PureSee) bilateral with a monovision target.",[13],{"label":47,"type":10,"description":48,"interventionNames":49},"Monofocal IOL VI and monofocal IOL III","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. In Arm ten (X) participants will receive a monofocal IOL (Vivinex XC1) bilateral or a monofocal IOL (Vivinex XY1) bilateral.",[13],[51,57,60,63,66,69,72,75,78,81],{"type":52,"name":53,"description":54,"armGroupLabels":55,"otherNames":56},"PROCEDURE","phacoemulsification and intraocular lens implantation","bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of a monofocal IOL (ZCB00) vs. an enhanced monofocal IOL (ICB00)",[9],null,{"type":52,"name":53,"description":58,"armGroupLabels":59,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of a monofocal IOL (Sensar 1 AAB00) vs. an enhanced monofocal IOL (ICB00)",[15],{"type":52,"name":53,"description":61,"armGroupLabels":62,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of a monofocal IOL (Vivinex XY1) vs. an enhanced monofocal IOL (Vivinex impress)",[19],{"type":52,"name":53,"description":64,"armGroupLabels":65,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of an enhanced monofocal IOL (Vivinex impress) in both eyes",[23],{"type":52,"name":53,"description":67,"armGroupLabels":68,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of an enhanced monofocal IOL (EnVista) vs. an enhanced monofocal IOL (LuxSmart)",[27],{"type":52,"name":53,"description":70,"armGroupLabels":71,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of an extended depth of focus IOL (Acrysof IQ Vivity) in both eyes if low to moderate irregular astigmatism is observed",[31],{"type":52,"name":53,"description":73,"armGroupLabels":74,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of an extended depth of focus IOL (IC-8 Apthera) in one eye if irregular astigmatism is observed",[35],{"type":52,"name":53,"description":76,"armGroupLabels":77,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of a monofocal IOL (EnVista) vs. an enhanced monofocal IOL (EnVista Aspire)",[39],{"type":52,"name":53,"description":79,"armGroupLabels":80,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of an enhanced depth of focus IOL (PureSee) in both eyes",[43],{"type":52,"name":53,"description":82,"armGroupLabels":83,"otherNames":56},"bilateral cataract surgery including phacoemulsification in individuals suffering from age-related cataract and intraocular lens implantation of a monofocal IOL (Vivinex XY1) in both eyes or a monofocal IOL (Vivinex XC1) in both eyes",[47],[85],{"name":86,"affiliation":5,"role":87},"Christina Leydolt, MD","PRINCIPAL_INVESTIGATOR",[89],{"name":86,"role":90,"phone":91,"phoneExt":56,"email":92},"CONTACT","+43 (01) 40 400 79480","christina.leydolt@meduniwien.ac.at",[94],{"facility":5,"status":95,"city":96,"state":56,"zip":56,"country":97,"countryCode":98,"cosmosGeoPoint":99,"geoPoint":104,"contacts":105},"RECRUITING","Vienna","Austria","AT",{"type":100,"coordinates":101},"Point",[102,103],16.37208,48.20849,{"lat":103,"lon":102},[106],{"name":86,"role":90,"phone":107,"phoneExt":56,"email":92},"+4314040079480",{"type":87,"investigatorFullName":109,"investigatorTitle":110,"investigatorAffiliation":5,"oldNameTitle":56,"oldOrganization":56},"Christina Leydolt","Assoc. Prof. PD Dr","100502425","intraindividual-comparison-of-emo-iols-100502425",false,"NCT05822089","Intraindividual Comparison of EMO IOLs","Comparison of Visual Outcomes of Enhanced Monofocal Intraocular Lenses","EMO","Inclusion Criteria:\n\n* Bilateral age-related cataract planned for phacoemulsification extraction and posterior IOL implantation\n* Age 50 to 100\n* Visual potential in both eyes of 20\u002F25 or better as determined by investigators estimation\n* Normal findings in medical history and physical examination unless the investigator considers an abnormality to be clinically irrelevant\n* Irregular Astigmatism (Acrysof IQ Vivity IOL, IC-8 Apthera IOL)\n* postoperativ binocular best corrected distance visual acuity (BCVA) ≥ 1.0 decimal (Arm ten (X))\n* Standard cataract surgery with bilateral implantation of a monofocal IOL (Vivinex XC1 or Vivinex XY1) (Arm ten (X))\n\nExclusion Criteria:\n\n* Preceding intraocular surgery or ocular trauma\n* Relevant other ophthalmic diseases that particularly effects the zonular apparatus (such as severe pseudoexfoliation syndrome, preceding cryocoagulation, trauma)\n* Pupil diameter \\\u003C 2.0 mm (photopic)\n* Laser treatment\n* Uncontrolled systemic or ocular disease\n* Pregnancy\u002FNursing\n* childbearing ability","ALL","50 Years","100 Years",{"count":123,"type":124},461,"ESTIMATED","INTERVENTIONAL",[127],"NA","The investigational devices are approved intraocular lenses (IOLs) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery. Cataract surgery with precedent bilateral randomized IOL implantation will be performed in subjects who have signed an informed consent form. Postoperative examinations will be implemented in accordance with the approved investigational plan.",[130],"Age Related Cataracts","2025-11-27",{"date":133,"type":134},"2025-12-05","ACTUAL",{"date":136,"type":134},"2021-12-13",{"date":138,"type":124},"2026-12-31",{"name":5,"class":6},1]