[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602995":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":38,"locations":44,"responsibleParty":77,"collaborators":37,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":37,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":37,"enrollmentInfo":90,"targetDuration":37,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":102,"overallStatus":47,"whyStopped":37,"lastUpdateSubmitDate":112,"lastUpdatePostDateStruct":113,"startDateStruct":116,"completionDateStruct":118,"leadSponsor":120,"locationsCount":121},{"fullName":5,"class":6},"Aula Dental Avanzada","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intraligamentary Injection Group","EXPERIMENTAL","Patients in this arm will receive intraligamentary anesthesia prior to endodontic access.",[13],"Procedure: Intraligamentary Injection",{"label":15,"type":16,"description":17,"interventionNames":18},"Inferior Alveolar Nerve Block Group","ACTIVE_COMPARATOR","Patients in this arm will receive standard inferior alveolar nerve block prior to endodontic access.",[19],"Procedure: Inferior Alveolar Nerve Block",[21,30],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Intraligamentary Injection","Intraligamentary local anesthesia will be administered using a standard dental syringe with 2% lidocaine and 1:100,000 epinephrine.",[9],[27,28,29],"Intraligamental anesthesia (ILA)","Periodontal ligament injection (PDL injection)","Intraligamentary anesthetic technique",{"type":22,"name":31,"description":32,"armGroupLabels":33,"otherNames":34},"Inferior Alveolar Nerve Block","Inferior alveolar nerve block will be performed with 2% lidocaine and 1:100,000 epinephrine using the conventional technique.",[15],[35,36],"Inferior alveolar nerve anesthesia","Inferior dental block",null,[39],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},"Guillem Esteve-Pardo, PhD","CONTACT","34965215755","guillem@clinicaesteve.com",[45,64],{"facility":46,"status":47,"city":48,"state":49,"zip":50,"country":51,"countryCode":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Clínica Dental 4","RECRUITING","Ferrol","A coruña","15402","Spain","ES",{"type":54,"coordinates":55},"Point",[56,57],-8.23293,43.48451,{"lat":57,"lon":56},[60],{"name":61,"role":41,"phone":62,"phoneExt":37,"email":63},"Pedro Barreiro-Gabeiras, DDS","34981358375","clinica4dental@gmail.com",{"facility":65,"status":47,"city":66,"state":66,"zip":67,"country":51,"countryCode":52,"cosmosGeoPoint":68,"geoPoint":72,"contacts":73},"Clínica Dental Esteve","Alicante","03001",{"type":54,"coordinates":69},[70,71],-0.48149,38.34517,{"lat":71,"lon":70},[74,75],{"name":40,"role":41,"phone":42,"phoneExt":37,"email":43},{"name":40,"role":76,"phone":37,"phoneExt":37,"email":37},"PRINCIPAL_INVESTIGATOR",{"type":76,"investigatorFullName":78,"investigatorTitle":79,"investigatorAffiliation":5,"oldNameTitle":37,"oldOrganization":37},"Guillem Esteve-Pardo","Principal Investigator - DDS, PhD (Bioengineering)","100602995","intraligamentary-vs-inferior-alveolar-nerve-block-for-pulpitis-a-randomized-clinical-trial-100602995",false,"NCT07130760","Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial","Is Intraligamentary Injection the Anesthesia of Choice for Symptomatic Irreversible Pulpitis in Mandibular Molars? A Multicenter Randomized Comparative Trial.","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Presenting with symptomatic irreversible pulpitis in a mandibular molar\n* Vital response to cold testing\n* Ability to understand and provide informed consent\n* Available for follow-up and data collection\n\nExclusion Criteria:\n\n* Known allergy to lidocaine or epinephrine\n* Pregnancy or breastfeeding\n* Use of analgesics or anti-inflammatory drugs in the previous 6 hours\n* Non-vital or previously treated teeth\n* Significant systemic disease (ASA III or above)\n* History of psychiatric or neurological disorders affecting pain perception",true,"ALL","18 Years",{"count":91,"type":92},52,"ESTIMATED","INTERVENTIONAL",[95],"NA","This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars. The goal is to determine which technique provides better pain control during endodontic treatment.",[98,99,100,101],"Symptomatic Irreversible Pulpitis (SIP)","Dental Pain","Inferior Alveolar Nerve Block Failure","Local Anesthesia",[103,104,105,106,107,108,109,110,111],"Inferior alveolar nerve block","Pulpitis Mandibular molars","Emergency dental treatment","Symptomatic irreversible pulpitis","Randomized clinical trial","Endodontics","Dental pain","Local anesthesia","Intraligamentary anesthesia","2025-08-16",{"date":114,"type":115},"2025-08-19","ACTUAL",{"date":117,"type":115},"2025-06-20",{"date":119,"type":92},"2027-07",{"name":5,"class":6},2]