[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100358882":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":28,"locations":37,"responsibleParty":57,"collaborators":19,"id":59,"slug":60,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":19,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":19,"enrollmentInfo":69,"targetDuration":19,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":81,"whyStopped":19,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Nova Scotia Health Authority","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Intranasal Capsaicin","EXPERIMENTAL","Separate patients will be given escalating doses of intranasal capsaicinoid spray",[13],"Other: Capsaicinoid",[15],{"type":6,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"Capsaicinoid","This is a tolerability study on doses lower than previously published for the use of intranasal capsaicinoid in the treatment of rhinitis",[9],null,[21,25],{"name":22,"affiliation":23,"role":24},"S Mark Taylor, MD FRCSC","Dalhousie University","PRINCIPAL_INVESTIGATOR",{"name":26,"affiliation":23,"role":27},"David WA Forner, MD","STUDY_DIRECTOR",[29,34],{"name":26,"role":30,"phone":31,"phoneExt":32,"email":33},"CONTACT","902 473 2222","8247","david.forner@dal.ca",{"name":22,"role":30,"phone":35,"phoneExt":19,"email":36},"902 473 5752","smarktaylor@eastlink.ca",[38],{"facility":39,"status":19,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Queen Elizabeth II Health Science Center","Halifax","Nova Scotia","B3H 2Y9","Canada","CA",{"type":46,"coordinates":47},"Point",[48,49],-63.57688,44.64269,{"lat":49,"lon":48},[52,55],{"name":53,"role":30,"phone":54,"phoneExt":19,"email":33},"David W Forner, MD","9027895932",{"name":56,"role":30,"phone":19,"phoneExt":19,"email":36},"s M Taylor, MD FRCSC",{"type":58,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100358882","intranasal-capsaicinoid-spray-100358882",false,"NCT03952845","Intranasal Capsaicinoid Spray","Tolerability of Intranasal Capsaicinoid Spray","Inclusion Criteria:\n\n* Healthy adults\n* American Association of Anesthesiology Class 1,\"A normal, healthy patient\" only\n\nExclusion Criteria:\n\n* Age less than 18 years\n* Pregnancy\n* Previous nasal or paranasal sinus surgery or radiation\n* Allergies to capsaicinoids or capsaicinoid containing products (any combination of sweet peppers, or hot peppers).",true,"ALL","18 Years",{"count":70,"type":71},30,"ESTIMATED","INTERVENTIONAL",[74],"NA","Rhinitis is inflammation of the inside of the nose. Symptoms of rhinitis include itchiness, sneezing, and a \"runny\" nose (rhinorrhea). There are many different causes for rhinitis, including allergies, age, different irritants in the air, overacting nervous system, and others.\n\nMany current treatments for rhinitis are not helpful or are unable to be used for long periods of time. Capsaicin (\"Kap-Sey-Uh-Sin\") is a natural product that is found in many spicy foods, including hot peppers. This natural product has been used as a lotion to prevent pain, and scientists have found that it may reduce the symptoms of rhinitis when used as a spray in the nose.\n\nHowever, capsaicin is known to cause a burning sensation. This study is needed so we can figure out what doses of capsaicin cause this burning sensation, and to what level these doses cause discomfort. Capsaicin can also cause a small degree of tearing from the eyes when used as a spray in the nose, and can also cause the nose to become \"runny\" (rhinorrhea).\n\nWhen the safest dose of capsaicin spray is found, that dose can be used to treat people with rhinitis that is not getting better from standard treatments.",[77,78,79],"Tolerance","Capsaicin","Rhinitis",[78,79],"NOT_YET_RECRUITING","2024-08-19",{"date":84,"type":85},"2024-08-21","ACTUAL",{"date":87,"type":71},"2025-08-01",{"date":89,"type":71},"2030-12-01",{"name":5,"class":6},1]