[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567091":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":29,"centralContacts":33,"locations":38,"responsibleParty":66,"collaborators":24,"id":68,"slug":69,"hasResults":70,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":24,"eligibilityCriteria":74,"healthyVolunteers":70,"sex":75,"minAge":76,"maxAge":77,"enrollmentInfo":78,"targetDuration":24,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":96,"whyStopped":24,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":106},{"fullName":5,"class":6},"Riphah International University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"GROUP A Intraneural Facilitation Therapy along with Home care plan","EXPERIMENTAL","Group A will receive 24 sessions of Intraneural Facilitation therapy, delivered three times weekly for eight weeks, each session lasting 60 minutes. Effects will be measured at baseline, post-intervention (after 8 weeks), and at a 2-months follow-up.",[13],"Other: Intraneural Facilitation Therapy",{"label":15,"type":10,"description":16,"interventionNames":17},"Group B Nerve Flossing Technique along with Home care plan","Group B will receive the nerve flossing technique for about 3 sets of 10 repetitions with an interval of 1 minutes between sets. A total of 24 sessions (3x\u002Fweek for 8 weeks) will be conducted, lasting 50-60 minutes each. The effects will be measured at baseline (pre-treatment), after week 8 (post-intervention), and at 2-month follow-up.",[18],"Other: Nerve Flossing Technique",[20,25],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"Intraneural Facilitation Therapy","* The initial hold, known as the facilitation hold, involves placing the contralateral joint in a maximal loose-pack position that will be comfortable for the patient. An illustration of this would be positioning the ankle joint on the contralateral side in full plantar flexion and inversion. Throughout the entire session, this position will be maintained using a stretch strap. It is crucial to emphasize that there is no muscle engagement in the joint where the facilitation takes place, only a slight stretch.\n* Once the pressure elevation occurs, the subsequent phase known as the secondary hold will be initiated to direct the augmented flow of epineurial blood toward the transperineurial vessels connecting the epiperineum and the endoneurial capillaries of the target area.\n* The final maneuver, the sub hold, leverages Bernoulli's principle to augment blood flow through the ischemic endoneurial capillaries experiencing heightened transmural pressure.",[9],null,{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":24},"Nerve Flossing Technique","Tibial Nerve:\n\n1. Passively flex the hip while dorsiflexing and everting the ankle to create tension; flex the knee to unload, then extend and plantarflex to reload.\n2. Flex the hip, extend the knee, and dorsiflex and evert the ankle to induce tension; flex the hip to unload, then extend and plantarflex to reload.\n3. Lift the leg, flex the hip, and extend the knee; dorsiflex and evert the ankle to induce tension, then plantarflex to unload.\n\nCommon Peroneal Nerve:\n\n1. Passively flex the hip and plantarflex and invert the ankle to induce tension; flex the knee to unload, then extend and dorsiflex to reload.\n2. Flex the hip, extend the knee, and plantarflex and invert the ankle to induce tension; flex the hip to unload, then extend and dorsiflex to reload.\n3. Lift the leg, flex the hip, and extend the knee; plantarflex and invert the ankle to induce tension, then dorsiflex to unload.",[15],[30],{"name":31,"affiliation":5,"role":32},"Hira Jabeen, MS-NMPT","STUDY_CHAIR",[34],{"name":31,"role":35,"phone":36,"phoneExt":24,"email":37},"CONTACT","03234116506","hira.jabeen@riphah.edu.pk",[39,58],{"facility":40,"status":24,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"Siddique Family Hospital","Gujranwala","Punjab Province","05228","Pakistan","PK",{"type":47,"coordinates":48},"Point",[49,50],74.18705,32.15567,{"lat":50,"lon":49},[53,55],{"name":54,"role":35,"phone":36,"phoneExt":24,"email":37},"Hira Jabeen",{"name":56,"role":57,"phone":24,"phoneExt":24,"email":24},"Amina Nazir, DPT","PRINCIPAL_INVESTIGATOR",{"facility":59,"status":24,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":60,"geoPoint":62,"contacts":63},"Social Security Hospital",{"type":47,"coordinates":61},[49,50],{"lat":50,"lon":49},[64,65],{"name":31,"role":35,"phone":36,"phoneExt":24,"email":37},{"name":56,"role":57,"phone":24,"phoneExt":24,"email":24},{"type":67,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100567091","intraneural-facilitation-therapy-and-nerve-flossing-technique-in-patients-with-diabetic-peripheral-neuropathy-100567091",false,"NCT06663670","Intraneural Facilitation Therapy and Nerve Flossing Technique in Patients With Diabetic Peripheral Neuropathy","Comparative Effects of Intraneural Facilitation Therapy and Nerve Flossing Technique on Pain, Balance, Gait, and Quality of Life in Patients With Diabetic Peripheral Neuropathy","Inclusion Criteria:\n\n* Type 2 diabetes mellitus (diagnosed by the physician)\n* Score \\>3 on Michigan Neuropathy Screening Instrument-Questionnaire and score \\>2 on MNSI-Physical Examination\n* Diabetic peripheral neuropathy symptoms below the ankle (numbness, tingling, burning, sharp pain, increased sensitivity, etc.)\n\nExclusion Criteria:\n\n* Presence of any other systemic disease rather than diabetes such as end-stage renal failure, uncontrolled hypertension, severe dyslipidemia, chronic liver disease, autoimmune disease, advanced chronic obstructive pulmonary disease, etc.\n* Diabetic ulcer in either foot\n* Total or partial amputation of lower extremities\n* Active inflammations or other inflammatory neuropathies including chronic inflammatory demyelinating polyneuropathy, proximal diabetic neuropathy, chemotherapy-induced peripheral neuropathy, autonomic neuropathies, or other neuropathies not associated with DM such as B12 deficiency\n* History of fracture, strain, history of trauma leading to nerve injuries in the last year.","ALL","50 Years","75 Years",{"count":79,"type":80},44,"ESTIMATED","INTERVENTIONAL",[83],"NA","The aim of this study is to determine the comparative effects of intraneural facilitation therapy and nerve flossing technique on pain, balance, gait, and quality of life in Diabetic peripheral neuropathy.",[86],"Diabetic Peripheral Neuropathy",[88,89,90,91,92,93,94,95],"Diabetes mellitus Type 2","Diabetic Neuropathy","Endoneurium","Epineurium","Gait","Pain","Peripheral Nerve","Quality of Life","NOT_YET_RECRUITING","2024-11-25",{"date":99,"type":100},"2024-11-26","ACTUAL",{"date":102,"type":80},"2024-12",{"date":104,"type":80},"2025-08",{"name":5,"class":6},2]