[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100590369":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":55,"collaborators":25,"id":58,"slug":59,"hasResults":60,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":60,"sex":65,"minAge":66,"maxAge":67,"enrollmentInfo":68,"targetDuration":25,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":25,"overallStatus":37,"whyStopped":25,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Ain Shams University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"KM Group","EXPERIMENTAL","Patients will receive a bolus of 0.5 mg\u002Fkg of ketamine given over a period of ten minutes followed by a constant infusion of 0.25 mg\u002Fkg\u002Fhr and a bolus dose of 30 mg\u002Fkg of magnesium sulfate during a 10-minute period followed by a continuous infusion of 9 mg\u002Fkg\u002Fhr.",[13],"Drug: Ketamine and Magnesium Sulfate",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group","PLACEBO_COMPARATOR","Patients will receive saline 0.9% as a control group.",[19],"Drug: Saline 0.9%",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"DRUG","Ketamine and Magnesium Sulfate",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Saline 0.9%",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Sarah A Afifi, MD","CONTACT","0501035864","Sarah606060@gmail.com",[36],{"facility":5,"status":37,"city":38,"state":25,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Cairo","11591","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.24967,30.06263,{"lat":46,"lon":45},[49,50,53],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":51,"role":52,"phone":25,"phoneExt":25,"email":25},"Maram I Elmazny, MD","PRINCIPAL_INVESTIGATOR",{"name":54,"role":52,"phone":25,"phoneExt":25,"email":25},"Sondos Ahmed, MD",{"type":52,"investigatorFullName":56,"investigatorTitle":57,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Sarah Ahmed","Lecturer of Anesthesia, Intensive care, and pain management, Faculty of Medicine, Ain Shams University, Cairo, Egypt.","100590369","intraoperative-combination-of-ketamine-and-magnesium-sulfate-infusions-on-postoperative-analgesia-in-open-rhinoplasty-100590369",false,"NCT06966518","Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Open Rhinoplasty","Effectiveness of Intraoperative Combination of Ketamine and Magnesium Sulfate Infusions on Postoperative Analgesia in Patients Undergoing Open Rhinoplasty: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age from 18 to 65 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I - II.\n* Scheduled for rhinoplasty under general anesthesia.\n\nExclusion Criteria:\n\n* Receiving analgesic or any medications since 48 hours before the surgery.\n* Drug addiction.\n* Cardiovascular disease.\n* Respiratory disease, renal, liver, metabolic and neurological disease.\n* Pregnancy or breast feeding.\n* Asthma.","ALL","18 Years","65 Years",{"count":69,"type":70},50,"ESTIMATED","INTERVENTIONAL",[73],"NA","The study aims to evaluate the effectiveness of intraoperative combination of ketamine and magnesium sulfate infusions on postoperative analgesia in patients undergoing open rhinoplasty.",[76,77,78,79,80],"Intraoperative","Ketamine","Magnesium Sulfate","Postoperative Analgesia","Rhinoplasty","2025-05-12",{"date":83,"type":84},"2025-05-13","ACTUAL",{"date":81,"type":84},{"date":87,"type":70},"2025-10-01",{"name":5,"class":6},1]