[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100601305":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":59,"collaborators":24,"id":63,"slug":64,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":24,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":24,"enrollmentInfo":72,"targetDuration":24,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":24,"overallStatus":36,"whyStopped":24,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"Tanta University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Lidocaine group","EXPERIMENTAL","Patients will receive an IV bolus (50 ml) of lidocaine (1mg\u002Fkg) diluted with saline over 10 min before induction of anesthesia. This will be followed by intraoperative lidocaine infusion in a dose of 1.5mg \u002Fkg\u002Fhr till the end of surgery.",[13],"Drug: Lidocaine",{"label":15,"type":10,"description":16,"interventionNames":17},"Dexmedetomidine group","Patients will receive an IV bolus (50 ml) of dexmedetomidine in dose 0.5 μg\u002Fkg over 10 min before induction of anesthesia. This will be followed by intraoperative dexmedetomidine infusion in a dose of 0.3 μg\u002Fkg\u002Fhr till the end of surgery.",[18],"Drug: Dexmedetomidine",[20,25],{"type":21,"name":22,"description":11,"armGroupLabels":23,"otherNames":24},"DRUG","Lidocaine",[9],null,{"type":21,"name":26,"description":16,"armGroupLabels":27,"otherNames":24},"Dexmedetomidine",[15],[29],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},"Dina H Alhassanin, Master","CONTACT","00201143441294","dhamdy420@gmail.com",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Tanta","El-Gharbia","31527","Egypt","EG",{"type":43,"coordinates":44},"Point",[45,46],31.00192,30.78847,{"lat":46,"lon":45},[49,50,53,55,57],{"name":30,"role":31,"phone":32,"phoneExt":24,"email":33},{"name":51,"role":52,"phone":24,"phoneExt":24,"email":24},"Ahmed M El-Sheikh, MD","SUB_INVESTIGATOR",{"name":54,"role":52,"phone":24,"phoneExt":24,"email":24},"Ashraf E Alzeftawy, MD",{"name":56,"role":52,"phone":24,"phoneExt":24,"email":24},"Atteia G Ibrahim, MD",{"name":58,"role":52,"phone":24,"phoneExt":24,"email":24},"Laila A Elahwal, MD",{"type":60,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"PRINCIPAL_INVESTIGATOR","Dina Hamdy Alhassanin","Assistant Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.","100601305","intraoperative-infusion-of-either-lidocaine-or-dexmedetomidine-on-regional-cerebral-oxygen-saturation-and-postoperative-delirium-in-elderly-patients-undergoing-abdominal-surgeries-100601305",false,"NCT07108764","Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries","Effect of Intraoperative Infusion of Either Lidocaine or Dexmedetomidine on Regional Cerebral Oxygen Saturation and Postoperative Delirium in Elderly Patients Undergoing Abdominal Surgeries","Inclusion Criteria:\n\n* Age ≥ 65years old.\n* Both sexes.\n* Physical status classification of II - III according to the American Society of Anesthesiologists (ASA).\n* Undergo elective non-cardiac surgeries.\n\nExclusion Criteria:\n\n* History of mental illness, neurological illness, or scoring less than 8 using the abbreviated mental test (AMT) before operation.\n* Severe hearing or visual impairment that may interfere with communication.\n* Severe renal or hepatic dysfunction.\n* Patients on central nervous system (CNS) medications (antipsychotics, anticonvulsants, antiparkinsonian, antidepressants).\n* Contraindications to lidocaine or dexmedetomidine \\[e.g., allergy, severe bradycardia, atrioventricular (AV) block\\].","ALL","65 Years",{"count":73,"type":74},100,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study aims to compare the effect of intraoperative infusion of either lidocaine or dexmedetomidine on the incidence of postoperative delirium (POD) in elderly patients undergoing major surgeries. It also aims to evaluate the impact of both medications on intraoperative regional cerebral oxygen saturation (rSO₂).",[80,22,26,81,82,83,84],"Intraoperative Infusion","Cerebral Oxygen Saturation","Postoperative Delirium","Elderly Patients","Abdominal Surgeries","2025-07-31",{"date":87,"type":88},"2025-08-07","ACTUAL",{"date":90,"type":88},"2025-04-17",{"date":92,"type":74},"2027-04-01",{"name":5,"class":6},1]