[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627443":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":67,"collaborators":26,"id":70,"slug":71,"hasResults":72,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":26,"eligibilityCriteria":76,"healthyVolunteers":72,"sex":77,"minAge":78,"maxAge":26,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":98,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Universitat Internacional de Catalunya","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Extraoral cementation (laboratory)","ACTIVE_COMPARATOR","Three-unit zirconia bridge cemented to Ti-bases extraorally on the working model under standardized laboratory conditions. Strain-gauge evaluation is performed in the laboratory prior to prosthesis delivery.",[13],"Procedure: Extraoral cementation on Ti-bases",{"label":15,"type":16,"description":17,"interventionNames":18},"Intraoral cementation (chairside)","EXPERIMENTAL","An identical three-unit zirconia bridge is cemented to Ti-bases intraorally following a standardized chairside protocol. The assembly is then removed and sent to the laboratory. Strain-gauge evaluation is performed approximately 1 week after intraoral cementation (7 ± 3 days).",[19],"Procedure: Intraoral cementation on Ti-bases",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"PROCEDURE","Extraoral cementation on Ti-bases","Extraoral (laboratory) cementation of a three-unit zirconia bridge to Ti-bases on the working model using a standardized protocol, with strain-gauge evaluation performed prior to prosthesis delivery.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Intraoral cementation on Ti-bases","Intraoral (chairside) cementation of an identical three-unit zirconia bridge to Ti-bases following a standardized protocol. The assembly is removed and sent to the laboratory, where strain-gauge evaluation is performed approximately 1 week later (7 ± 3 days).",[15],[32],{"name":33,"affiliation":5,"role":34},"MARTA VALLES, DDS, PhD","PRINCIPAL_INVESTIGATOR",[36,40],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","+34 619747903","mvalles@uic.es",{"name":41,"role":37,"phone":42,"phoneExt":26,"email":43},"Patricia Freire, DDS","+34 686054668","patricia.freire@uic.es",[45],{"facility":46,"status":26,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Clínica Universitària d'Odontologia UIC Barcelona","Sant Cugat del Vallès","Barcelona","08195","Spain","ES",{"type":53,"coordinates":54},"Point",[55,56],2.08611,41.47063,{"lat":56,"lon":55},[59,61,63,64],{"name":60,"role":37,"phone":38,"phoneExt":26,"email":39},"MARTA VALLES, Principal Investigator",{"name":62,"role":37,"phone":42,"phoneExt":26,"email":43},"PATRICIA FREIRE, Sub Investigator",{"name":33,"role":34,"phone":26,"phoneExt":26,"email":26},{"name":65,"role":66,"phone":26,"phoneExt":26,"email":26},"PATRICIA FREIRE, DDS","SUB_INVESTIGATOR",{"type":34,"investigatorFullName":68,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"Marta Vallés Rodríguez","DDS, phD","100627443","intraoral-vs-extraoral-cementation-of-zirconia-bridges-on-ti-bases-microstrain-evaluation-100627443",false,"NCT07448701","Intraoral vs Extraoral Cementation of Zirconia Bridges on Ti-Bases: Microstrain Evaluation","Influence of Cementation Technique on Microstrain in Three-Unit Bridges on Ti-Bases Evaluated by Strain Gauges","Inclusion Criteria:\n\n* Adults (≥18 years old) in good general health.\n* Presence of an edentulous space requiring rehabilitation with a three-unit implant-supported fixed bridge.\n* Presence of two already osseointegrated Essential Cone implants (Klockner) indicated for a three-unit implant-supported restoration in the edentulous area.\n* Ability and willingness to participate and attend study visits and follow-up.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* ASA III or ASA IV.\n* Current or previous treatment with bisphosphonates.\n* Smoking \\>10 cigarettes\u002Fday.\n* Extraction in the study area \\\u003C3 months before implant placement with incomplete healing.\n* Guided bone regeneration in the study area with \\\u003C6 months of healing time.\n* Signs of active periodontal disease (e.g., poor plaque control and\u002For bleeding on probing above acceptable levels).","ALL","18 Years",{"count":80,"type":81},30,"ESTIMATED","INTERVENTIONAL",[84],"NA","This prospective clinical study compares two cementation techniques for implant-supported zirconia fixed partial dentures on titanium bases (Ti-bases): extraoral cementation performed on the working model and intraoral cementation performed chairside. Thirty clinical cases with two osseointegrated implants requiring a multi-unit zirconia restoration will be recruited at the UIC Dental Clinic. For each case, two restorations with identical design will be produced: one will be cemented extraorally (control) and an identical replica will be cemented intraorally (test). Micro-deformation will be assessed as peri-implant microstrain (µε) using a standardized strain-gauge setup and the same recording protocol for both techniques. The primary analysis compares microstrain between intraoral and extraoral cementation within each case; implant\u002Fprosthetic events will be recorded descriptively.",[87,88],"Biomechanical Phenomena","Partial Edentulism",[90,91,92,93,94,95,96,97],"titanium base","ti-base","zirconia bridge","intraoral cementation","passive fit","screw-retained restoration","strain gauge","CAD\u002FCAM zirconia","NOT_YET_RECRUITING","2026-02-28",{"date":101,"type":102},"2026-03-04","ACTUAL",{"date":104,"type":81},"2026-03",{"date":106,"type":81},"2027-06",{"name":5,"class":6},1]