[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100571422":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":56,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":25,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":86,"whyStopped":25,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Services Institute of Medical Sciences, Pakistan","OTHER_GOV",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Group A will undergo intraosseous dexamethasone injection after 3rd molar surgery","EXPERIMENTAL","In Group A, patients will receive 4 mg dexamethasone intraosseous injection into the bone distal to the socket of impacted third molar immediately after extraction of the third molar and before suturing",[13],"Procedure: Intraosseous dexamethasone injection after 3rd molar surgery",{"label":15,"type":16,"description":17,"interventionNames":18},"Group B will undergo submucosal dexamethasone injection after 3rd molar surgery","ACTIVE_COMPARATOR","In Group B, patients will receive 4 mg dexamethasone submucosal injection into the buccal vestibule opposite to the surgical site of impacted third molar immediately after surgery.",[19],"Procedure: Submucosal dexamethasone injection after 3rd molar surgery",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Intraosseous dexamethasone injection after 3rd molar surgery",[9],null,{"type":22,"name":27,"description":17,"armGroupLabels":28,"otherNames":25},"Submucosal dexamethasone injection after 3rd molar surgery",[15],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Mahreen Mahmood, BDS","CONTACT","092-3319440050","mahreenmahmood510@gmail.com",[36],{"facility":37,"status":25,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Services Institute of Medical Sciences Lahore","Lahore","Punjab Province","54000","Pakistan","PK",{"type":44,"coordinates":45},"Point",[46,47],74.35071,31.558,{"lat":47,"lon":46},[50,52],{"name":31,"role":32,"phone":51,"phoneExt":25,"email":34},"092-3366297558",{"name":53,"role":32,"phone":54,"phoneExt":25,"email":55},"Professor Hafiz Aamir Iqbal","092-3334955789","Haafiz.amer.iqbal@gmail.com",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Mahreen Mahmood","OMFS Resident","100571422","intraosseous-versus-submucosal-dexamethsone-injection-in-third-molar-surgery-100571422",false,"NCT06720051","Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery","Efficacy of Intraosseous Versus Submucosal Dexamethasone Injection in Terms of Pain, Facial Swelling and Interincisal Opening Among Patients Undergoing Third Molar Surgery","Inclusion Criteria:\n\n* Patients undergoing mandibular third molar surgery\n* Age 18 to 35 years\n* Male and female\n\nExclusion Criteria:\n\n* Uncontrolled systemic medical problems including diabetes and hypertension\n* Presence of any cyst, tumor, or other pathological condition in the molar area\n* Presence of any craniofacial anomalies, congenital deformities or syndromes\n* Patients with known adverse effects of steroid use\n* Previous history of orthodontic treatment\n* Have a pain disorder or taking pain medications\n* Pregnant and lactating mothers","ALL","18 Years","35 Years",{"count":71,"type":72},76,"ESTIMATED","INTERVENTIONAL",[75],"NA","The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection. The main questions it aims to answer are:\n\nDoes intraosseous dexamethasone injection provide better pain relief and lessen facial swelling than submucosal dexamethasone injection Does intraosseous dexamethasone injection provide better interincisal opening than submucosal dexamethasone injection Researcher will compare both the techniques to see if intraosseous dexamethasone injection works better than submucosal dexamethasone injection\n\nParticipants will:\n\nBe assessed at 3rd and 7th day postoperatively Pain will be assessed through visual analog scale score Facial measurement will be calculated as horizontal measurement plus vertical measurement divided by 2, where horizontal measurement will be taken as the distance between corner of the mouth and the earlobe attachment, and vertical measurement will be taken as distance from outer canthus of the eye to the angle of jaw.\n\nInterincisal opening will be measured from the incisal edge of the maxillary central incisors to the incisal edge of mandibular central incisors at the midline by using millimeter ruler",[78],"Third Molar Surgery",[80,81,82,83,84,85],"intraosseous dexamethasone injection","submucosal dexamethasone injection","Third molar surgery","facial pain in third molar surgery","facial swelling in 3rd molar surgery","interincisal opening in third molar surgery","NOT_YET_RECRUITING","2024-12-09",{"date":89,"type":90},"2024-12-13","ACTUAL",{"date":92,"type":72},"2025-06-01",{"date":94,"type":72},"2025-11-30",{"name":5,"class":6},1]